Search results for "ATRP"
showing 9 items of 19 documents
SELF-ASSEMBLING POLY(HYDROXYETHYL ASPARTAMIDE)-GRAFT POLYMETHACRYLATE COPOLYMERS OBTAINED BY ATOM TRANSFER RADICAL POLYMERIZATION
2009
ATRP AS AN EFFICIENT METHOD TO PRODUCE BRUSH COPOLYMERS OF HYALURONIC ACID
2012
Sintesi e caratterizzazione di vettori polimerici a base di una poliidrossietilaspartammide ottenuti mediante ATRP per la veicolazione di SiRNA
2012
SYNTHESIS OF INULIN-GRAFT COPOLYMERS VIA GRAFTING- FROM ATRP TECHNIQUE. A NEW FRONTIER FOR MODIFICATION OF NATURAL POLYSACCHARIDES
2012
Polyaspartamide-graft-polymethacrylate nanoparticles for doxorubicin delivery
2011
Synthesis and characterization of polyaspartamide copolymers obtained by ATRP for nucleic acid delivery
2014
Abstract Nucleic acid molecules such as small interfering RNAs (siRNAs) and plasmidic DNAs (pDNAs) have been shown to have the potential to be of therapeutic value in different human diseases. Their practical use is however compromised by the lack of appropriate release systems. Delivered as naked molecules, siRNAs/pDNAs are rapidly degraded by extracellular nucleases thus considerably reducing the amount of molecule which can reach the target cells. Additionally, the anionic charge of the phosphate groups present on the siRNAs/pDNAs backbone, disfavors the interaction with the negatively charged surface of the cell membrane. In this paper we describe the generation of a novel polymer able …
New hyaluronic acid based brush copolymers synthesized by atom transfer radical polymerization
2013
Systematic Study of a Library of PDMAEMA-Based, Superparamagnetic Nano-Stars for the Transfection of CHO-K1 Cells.
2017
The introduction of the DNA into mammalian cells remains a challenge in gene delivery, particularly in vivo. Viral vectors are unmatched in their efficiency for gene delivery, but may trigger immune responses and cause severe side-reactions. Non-viral vectors are much less efficient. Recently, our group has suggested that a star-shaped structure improves and even transforms the gene delivery capability of synthetic polycations. In this contribution, this effect was systematically studied using a library of highly homogeneous, paramagnetic nano-star polycations with varied arm lengths and grafting densities. Gene delivery was conducted in CHO-K1 cells, using a plasmid encoding a green fluore…
Silseskwioksany i ich zastosowanie w syntezie materiałów polimerowych
2015
Artykuł stanowi przegląd literatury dotyczącej syntezy oraz charakterystyki materiałów polimerowych zawierających silseskwioksany (POSS). Przedstawiono metody otrzymywania hybrydowych materiałów polimerowych z udziałem funkcjonalizowanych POSS na drodze click chemistry, polikondensacji, poliaddycji, metatezy z otwarciem pierścienia ipolimeryzacji rodnikowej zarówno konwencjonalnej, jak i kontrolowanej (ATRP).