Search results for "ATS"

Una experiència de coaching grupal i desenvolupament de competències emprenedores en estudiants universitaris

2012

L'ocupabilitat dels estudiants universitaris sovint suposa un desajust entre el perfil professional i el perfil buscat per les empreses, impulsades per criteris d'originalitat, aplicabilitat, viabilitat i estructura; una nova avaluació, d'acord amb els mateixos criteris, es fa pels professors externs a l'assignatura i, finalment, es remeten a la Càtedra d'Emprenedoria, demanant avaluació i les diverses subvencions i subsidis que podrien rebre si decideixen dur a terme el projecte. Els resultats obtinguts segueixen un patró establert en els diferents grups. Aquells que, d'acord amb els criteris anteriors (originalitat, aplicabilitat, viabilitat i estructura), obtenen millors resultats a trav…

Pharmacological activation of CB2 receptors counteracts the deleterious effect of ethanol on cell proliferation in the main neurogenic zones of the a…

2015

Chronic alcohol exposure reduces endocannabinoid activity and disrupts adult neurogenesis in rodents, which results in structural and functional alterations. Cannabinoid receptor agonists promote adult neural progenitor cell (NPC) proliferation. We evaluated the protective effects of the selective CB1 receptor agonist ACEA, the selective CB2 receptor agonist JWH133 and the fatty-acid amide-hydrolase (FAAH) inhibitor URB597, which enhances endocannabinoid receptor activity, on NPC proliferation in rats with forced consumption of ethanol (10%) or sucrose liquid diets for 2 weeks. We performed immunohistochemical and stereological analyses of cells expressing the mitotic phosphorylation of his…

"Kolektīvais ģēnijs: inovāciju vadības māksla un prakse. Rīga : Lauku Avīze, 2014. 287.lpp." - pārdomas par grāmatu

2017

Universities' mundaneness and regional engagement : Setting the stage

2022

This chapter introduces the main logic of this volume, which starts from the grassroots level of universities’ “everyday” engagements, looking at the manifold ways in which university knowledge agents build connections with multiple regional partners across the public and private sectors, and civic society more generally. Roles, functions and normative orientations of universities in the context of their surrounding regions have, in many cases, been taken for granted and, thus, have not been systematically addressed and/or still lack theorizing, due to the focus being on extraordinary, large-scale and eye-catching activities, and financially impressive transactions such as patents and spin-…

Universities and regions: New insights and emerging developments

2022

In this concluding chapter, the editors take stock of the empirical findings across the cases and levels of analysis and link the empirical evidence to the analytical framework presented in Chapter 2. In so doing, we revisit the interplay between macro, meso, and micro dimensions of the environments as well as the temporality in which higher education institutions (HEIs) operate, which, taken together, help shape the mundane (everyday) or routine behaviours of actors within HEIs. The editors conclude by suggesting that the empirical evidence and conceptual insights advanced in this volume represent a needed first step, yet more needs to be done (future studies) to further unpack how the dyn…

Unpacking Mundaneness : A novel conceptual framework for universities and regional engagement

2022

In this chapter, we debate the current view on university-regional engagements and suggest a renewed theoretical framework based on four main elements – macro, meso, micro dimensions, as well as a meta-dimension of temporality that cuts across all levels. The macro environment is typically defined as pertaining to public policies, culture, laws, and economy, while the meso environment includes links between the macro (societal) forces and the micro (agents) level through intermediate institutions and structures and is characterized by the processes and mechanisms of interaction of different actors. The micro level is about agency – organizations or individuals/groups within organizations – …

Central functional response to the novel peptide cannabinoid, hemopressin.

2013

Hemopressin is the first peptide ligand to be described for the CB₁ cannabinoid receptor. Hemopressin acts as an inverse agonist in vivo and can cross the blood-brain barrier to both inhibit appetite and induce antinociception. Despite being highly effective, synthetic CB₁ inverse agonists are limited therapeutically due to unwanted, over dampening of central reward pathways. However, hemopressin appears to have its effect on appetite by affecting satiety rather than reward, suggesting an alternative mode of action which might avoid adverse side effects. Here, to resolve the neuronal circuitry mediating hemopressin's actions, we have combined blood-oxygen-level-dependent, pharmacological-ch…

Cannabinoid type 1 receptor modulates intestinal propulsion by an attenuation of intestinal motor responses within the myenteric part of the peristal…

2007

Cannabinoid-1 (CB1) receptor activation affects gastrointestinal propulsion in vivo. It was our aim to further characterize the involved myenteric mechanisms in vivo and in vitro. In CB1(-/-) mice and wild-type littermates we performed in vivo transit experiments by charcoal feeding and in vitro electrophysiological recordings in mouse small intestinal smooth muscle. Ascending neuronal contraction (ANC) following electrical field stimulation was studied in rat ileum in a partitioned organ bath separating the aboral stimulation site from the oral recording site. The knockout animals displayed an accelerated upper gastrointestinal transit compared to control animals. The CB1 receptor antagoni…

Sāpju vadīšana pediatriskiem pacientiem apdeguma gadījumā

2019

Bakalaura darba tēma – Sāpju vadīšana pediatriskiem pacientiem apdegumu gadījumā. Šī tēma ir aktuāla, jo statistika liecina, ka katru gadu bērnu apdegumu skaits arvien pieaug. Salīdzinot 2016. gada un 2017. gada datus, apdegumu skaits bērnu vidu pieaudzis par septiņiem gadījumiem. Lielākā riska grupa apdegumu traumām ir bērni vecuma posmā no trīs gadu vecuma, kas applaucējumus vairumā iegūst vecāku neuzmanības dēļ. Darba izstrādāšanas mērķis – Noskaidrot sāpju vadīšanas principus pediatriskiem pacientiem apdegumu gadījumā. Darba uzdevumi ir izanalizēt un apkopot iegūtos datus par sāpju vadīšanas principiem pediatriskiem pacientiem apdegumu gadījumā. Analizēt Virdžīnijas Hendersones māszinīb…

Influence of gamma-aminobutyric acid on baclofen intestinal absorption.

1994

Since previous studies suggested that baclofen absorption in the rat middle intestine was inhibited by beta-alanine and therefore mediated, at least in part, by the beta-aminoacid carrier, we focused our new studies on the analysis of the possible inhibition of the drug by a gamma-aminoacid model compound, gamma-aminobutyric acid (GABA). A rat jejunum in situ study was undertaken in order to evaluate the effect of GABA on baclofen absorption and to establish the inhibition model. Assays using isotonic perfusion solutions of 0.5 mM baclofen with starting GABA concentrations ranging from 0 to 100 mM are reported. The results show that the absorption rate pseudoconstants of the drug decrease a…