Search results for "ATf"

Ethanol-Mediated Stress Promotes Autophagic Survival and Aggressiveness of Colon Cancer Cells via Activation of Nrf2/HO-1 Pathway

2019

Epidemiological studies suggest that chronic alcohol consumption is a lifestyle risk factor strongly associated with colorectal cancer development and progression. The aim of the present study was to examine the effect of ethanol (EtOH) on survival and progression of three different colon cancer cell lines (HCT116, HT29, and Caco-2). Our data showed that EtOH induces oxidative and endoplasmic reticulum (ER) stress, as demonstrated by reactive oxygen species (ROS) and ER stress markers Grp78, ATF6, PERK and, CHOP increase. Moreover, EtOH triggers an autophagic response which is accompanied by the upregulation of beclin, LC3-II, ATG7, and p62 proteins. The addition of the antioxidant N-acetyl…

Design, synthesis and characterization of a theranostic nanoplatform for tumor site-specific delivery of doxorubicin

2022

Latent heat flux variability and response to drought stress of black poplar: A multi-platform multi-sensor remote and proximal sensing approach to re…

2022

Abstract High-throughput mapping of latent heat flux (λET) is critical to efforts to optimize water resources management and to accelerate forest tree breeding for improved drought tolerance. Ideally, investigation of the energy response at the tree level may promote tailored irrigation strategies and, thus, maximize crop biomass productivity. However, data availability is limited and planning experimental campaigns in the field can be highly operationally complex. To this end, a multi-platform multi-sensor observational approach is herein developed to dissect the λET signature of a black poplar (Populus nigra) breeding population (“POP6”) at the canopy level. POP6 comprised more than 4600 …

Carbonate Platform-Basin Transition in SW Sicily. Implications for the Petroleum Exploration in the Maghrebian Thrust and Fold Belt

2009

A segment of the Ionian margin in the Sciacca zone, Sicily.

2008

A Triassic carbonate platform edge in the Sciacca zone: implications for the accretion of the Maghrebian chain in southwestern Sicily

2008

Fossil wood in Middle–Upper Jurassic marine sedimentary cycles of France: relations with climate, sea-level dynamics, and carbonate-platform environm…

1998

Abstract Vegetation, climate, and sea-level oscillations interact in complex ways. Intuition suggests that climatic variations are recorded in geological deposits by both fossil phytoclasts and sediments. Therefore investigation of palaeobotanical remains within a precise sedimentological framework may help to decipher this much-debated interaction. A database of 129 Jurassic (Bathonian–Oxfordian) fossil wood samples from France is used here as a case study. The palaeoenvironment (freshwater swamp, carbonate lagoon, shoreface, argillaceous offshore) and the second-order relative sea-level phases were determined for each datum. There is no correlation between the wood genera distribution and…

One My scale subsidence of carbonate sedimentary bodies and the viscosity of the lower crust

2004

Abstract The possibility of flow of the lower crust under the load produced by carbonate sedimentary accumulations is investigated through the example of the Paris basin during the Middle Jurassic (i.e. Bathonian). Depositional geometries, water depths and sedimentary environments have been estimated and correlated for 164 sites spread over a surface of 380 per 220 km for three successive periods lasting each less than 0.8 My. A signal of relative vertical displacement has been extracted from water-depth and sedimentary thickness. Data have then been interpolated to produce maps of velocity of vertical displacement, sedimentation rate, water depth, and water-depth variation between two peri…

Carbonate platform-basin systems of Sicily through the Triassic/Jurassic Boundary: Stratigraphic constraints for the paleogeographic reconstructions.

2004

Yeast β-glucans and microalgal extracts modulate the immune response and gut microbiome in Senegalese sole (Solea senegalensis)

2019

One bottleneck to sustainability of fish aquaculture is the control of infectious diseases. Current trends include the preventive application of immunostimulants and prebiotics such as polysaccharides. The present study investigated how yeast β-glucan (Y), microalgal polysaccharide-enriched extracts (MAe) and whole Phaeodactylum tricornutum cells (MA) modulated the gut microbiome and stimulated the immune system in Senegalese sole (Solea senegalensis) when administered by oral intubation. Blood, intestine and spleen samples were taken at 3 h, 24 h, 48 h and 7 days after treatment. The short-term response (within 48 h after treatment) consisted of up-regulation of il1b and irf7 expression in…