Search results for "AVAILABILITY"

showing 10 items of 510 documents

Biocompatible Lipid Nanoparticles as Carriers to Improve Curcumin Efficacy in Ovarian Cancer Treatment

2017

Curcumin is a natural molecule with proved anticancer efficacy on several human cancer cell lines. However, its clinical application has been limited due to its poor bioavailability. Nanocarrier-based drug delivery approaches could make curcumin dispersible in aqueous media, thus overtaking the limits of its low solubility. The aim of this study was to increase the bioavailability and the antitumoral activity of curcumin, by entrapping it into nanostructured lipid carriers (NLCs). For this purpose here we describe the preparation and characterization of three kinds of curcumin-loaded NLCs. The nanosystems allowed the achievement of a controlled release of curcumin, the amounts of curcumin r…

nanostructured lipid carriers curcumin drug release cancer epithelial ovarian cellsCurcuminNanoparticleAdministration Oral02 engineering and technologyPharmacologynanostructured lipid carrier03 medical and health scienceschemistry.chemical_compound0302 clinical medicineDrug Delivery SystemsNanoparticleSettore BIO/10 - BiochimicamedicineHumanscancerParticle SizeDrug Carrierdrug releaseCell ProliferationOvarian NeoplasmsDrug CarriersOvarian NeoplasmChemistry (all)General ChemistryLipid021001 nanoscience & nanotechnologyBiocompatible materialmedicine.diseaseControlled releaseLipidsBioavailabilitychemistryAgricultural and Biological Sciences (all)Settore CHIM/09 - Farmaceutico Tecnologico Applicativo030220 oncology & carcinogenesisDrug deliveryCurcuminNanoparticlesFemaleNanocarriers0210 nano-technologyGeneral Agricultural and Biological SciencesOvarian cancerDrug Delivery Systemepithelial ovarian cellHuman
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The association between parental education, living arrangements and dietary habits among overweight and obese Norwegian children aged 6-10 years : “F…

2016

Masteroppgave folkehelsevitenskap - Universitetet i Agder 2016 Children´s dietary patterns have changed the passed decades. Children are more overweight and obese, and social inequalities related to this topic are discussed among all societies. The purpose of the master thesis was to explore the association between the sociodemographic factors parental education and living arrangements and the availability and intake of selected food items and total energy intake and macronutrient intake among overweight and obese Norwegian children aged 6-10 years. The thesis is an extension of the theory that is used in the article. This thesis begins with an introduction, which further expands to the ela…

obesitytilgjengelighet av matvarerbarnparental educationliving arrangementsfood availabilityVDP::Medical disciplines: 700::Health sciences: 800::Nutrition: 811foreldres utdannelsebosituasjonME516childrenkostholdsvaneroverweightdietary habitsovervekt
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Optimization of the Red Tilapia (Oreochromis spp.) Viscera Hydrolysis for Obtaining Iron-Binding Peptides and Evaluation of In Vitro Iron Bioavailabi…

2020

Iron deficiencies continue to cause significant health problems in vulnerable populations. A good strategy to combat mineral deficiency includes fortification with iron-binding peptides. This research aims to determine the optimal conditions to hydrolyze red tilapia viscera (RTV) using Alcalase 2.4 L and recovery of iron-binding protein hydrolysate. The result showed that under the optimal hydrolysis condition including pH 10, 60 &deg

protein hydrolysisHealth (social science)food.ingredientHydrolyzed proteinsurface response designMineral deficiencyPlant Sciencelcsh:Chemical technologyHealth Professions (miscellaneous)MicrobiologyArticleAlcalaseHydrolysateHydrolysisfoodmedicinelcsh:TP1-1185Food scienceCaco-2 cellsbiologyChemistryTilapiamedicine.diseasebiology.organism_classificationBioavailabilityFerritinOreochromisbiology.proteiniron bioavailabilityiron-binding activityFood ScienceFoods
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Impacts of reduced Lepidurus arcticus availability on brown trout life history traits in a mountain reservoir

2020

Lepidurus arcticus (the Arctic tadpole shrimp) is a vulnerable keystone species in Arctic and alpine water bodies where its occurrence and population size may influence the viability and life history traits of resident salmonids. Using data from a Norwegian mountain hydropower reservoir, Aursjoen, we illustrate how reduced availability of L. arcticus as prey resulted in the reduced condition, growth and delayed maturation of resident brown trout (Salmo trutta). We further link changes in the relative abundance of L. arcticus as prey to changing reservoir conditions, e.g. water level changes in the spring period, thereby establishing an indirect link between reservoir operation regimes and b…

ravintovesistöjen säännöstelyBranchiopodanutritiontaimencrustaceansprey availabilitykannanvaihteluthydropower reservoirtekoaltaatäyriäisetkeystone species
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On the degree of binder activity of reclaimed asphalt and degree of blending with recycling agents

2020

It is common practice to assume full blending of the aged binder of reclaimed asphalt (RA) within the design of new asphalt mixtures. Although being practical, this assumption has often led designers to asphalt mixtures lacking binder. Hence, going towards recycled asphalt mixtures (RAM) there is a need to have a better understanding of the blending phenomena, to have a general agreement on terminology and finally adapting RA classification and mix design procedures accordingly. This manuscript aims at being both a reference and stimulus for the scientific community to work in this direction and on this basis provides a nomenclature and a theoretical framework of the blending phenomena. The…

recycling agent050210 logistics & transportationdegree of blendingWaste managementdegree of activity05 social sciences0211 other engineering and technologies02 engineering and technologyrecycling agent blending phenomenablending phenomena; degree of activity; degree of availability; degree of blending; recycled asphalt; recycling agentblending phenomenaDegree (temperature)degree of availabilityAsphaltrecycled asphalt021105 building & construction0502 economics and businessCivil and Structural EngineeringMathematics
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Strontium Uptake and Intra-Population 87Sr/86Sr Variability of Bones and Teeth—Controlled Feeding Experiments With Rodents (Rattus norvegicus, Cavia …

2020

Strontium isotopes in biogenic apatite, especially enamel, are widely employed to determine provenance and track migration in palaeontology and archaeology. Body tissues record the 87Sr/86Sr of bioavailable Sr of ingested food and water. To identify non-local individuals, knowledge of the 87Sr/86Sr of a non-migratory population is required. However, varying factors such as tissue turnover rates, feeding selectivity, Sr content, digestibility of food, and the ingestion of mineral dust can influence body tissue 87Sr/86Sr. To evaluate the Sr contribution of diet and water to mammalian hard tissues 87Sr/86Sr, controlled feeding studies are necessary. Here we present 87Sr/86Sr from controlled fe…

rodentstrontium isotopespopulation variabilityenamelfaecefeeding studybioavailabilitybone
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Dead wood profile of a semi-natural boreal forest – implications for sampling

2019

Dead wood profile of a forest is a useful tool for describing forest characteristics and assessing forest disturbance history. Nevertheless, there are few studies on dead wood profiles, including both coarse and fine dead wood, and on the effect of sampling intensity on the dead wood estimates. In a semi-natural boreal forest, we measured every dead wood item over 2 cm in diameter from 80 study plots. From eight plots, we further recorded dead wood items below 2 cm in diameter. Based on these data we constructed the full dead wood profile, i.e. the overall number of dead wood items and their distribution among different tree species, volumes of different size and decay stage categories. We …

saproxylic0106 biological sciencesforest disturbance dynamicsDIVERSITYDEBRISSemi naturalDead wood010501 environmental sciencesECOLOGYpuulajit010603 evolutionary biology01 natural sciencesSWEDISH FORESTSRICHNESSlcsh:ForestryINHABITING FUNGICOARSElahopuutconiferous forest0105 earth and related environmental sciencesSAPROXYLIC BEETLES4112 ForestryhavumetsätAVAILABILITYEcological Modelingcoarse woody debrisTaigaSampling (statistics)ForestryForestry15. Life on landmetsätfine woody debrisFINElcsh:SD1-669.5Environmental scienceforest structure
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Ultra Reliable Communication in 5G Networks: A Dependability-based Availability Analysis in the Space Domain

2017

Master's thesis Information- and communication technology IKT591 - University of Agder 2017 As our daily life is becoming more dependent on wireless and mobile services, seamless network connectivity is of utmost importance. Wireless networks are expected to handle the growing demand for applications which require higher capacity, without failure. Therein, wireless connectivity is regarded as an essential requirement for a wide range of applications in order to support exible and cost-e ective services. As part of the fth generation (5G) communication paradigm, ultra reliable communication (URC) is envisaged as an important technology pillar for providing anywhere and anytime services to en…

space domain analysisPPPIKT591availabilityURCsimulationVDP::Teknologi: 500::Informasjons- og kommunikasjonsteknologi: 5505GVoronoi tessellationdependability
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An equation to calculate the availability for the k-out-of-n system

2016

Reliability and availability (R&A) analyses are primary phases in management of complex systems and play a fundamental role in products and services quality. Management of maintenance activities has to be based on optimisation to simultaneously improve the operative conditions of the system. Maintenance optimization can be effeectively pursued by the RCM (Reliability-centered maintenance) approach. The authors demonstrate the global improvement of R&A by applying the RCM to the results derived by the FMECA (Failure Modes Effects and Criticality Analysis). Many efforts have been made to improve traditional methodologies of analysis, mainly tending to reduce the imprecision on data related to…

stationary availabilityk-out-of-n system
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Dyvalocca : un projet pour l'étude des nuages bas de saison sèche sur la façade atlantique de l'Afrique centrale et de leur impact bioclimatique sur …

2020

Low-level clouds are key components of the climate but are not well represented in weather and climate models. Recently it has been shown that an extensive low-level cloud cover develops during the June-September main dry season in western equatorial Africa, from the coastal plains of Gabon and Congo-Brazzaville to the inland plateaus downstream of the low-mountain crests. Such a cloudy main dry season is unique in the moist Tropics and is likely to explain the presence of the densest and evergreen forests of Central Africa as evapotranspiration is low and the quality of light is high. The ANR-DFG funded “DYVALOCCA” project will conduct from 2020 to 2022 a field campaign, raise existing in-…

water and light availabilityAfrique CentraleCentral Africa[SDU.STU.CL] Sciences of the Universe [physics]/Earth Sciences/Climatology[SDU.STU.CL]Sciences of the Universe [physics]/Earth Sciences/Climatologyvariabilityvariabilitéprocessesprocessusnuages basdisponibilité en eau et lumièrelow clouds
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