Search results for "AWS"
showing 10 items of 239 documents
Multiphysical Modeling of Transport Phenomena During Laser Welding of Dissimilar Steels
2016
Abstract The success of new high-strength steels allows attaining equivalent performances with lower thicknesses and significant weight reduction. The welding of new couples of steel grades requires development and control of joining processes. Thanks to high precision and good flexibility, laser welding became one of the most used processes for joining of dissimilar welded blanks. The prediction of the local chemical composition in the weld formed between dissimilar steels in function of the welding parameters is essential because the dilution rate and the distribution of alloying elements in the melted zone determines the final tensile strength of the weld. The goal of the present study i…
The effect of microscale pore structure on matrix diffusion—a site-specific study on tonalite
1997
Abstract The matrix diffusion of non-sorbing tracers was studied in rocks from the Syyry area, Central Finland (SY1). The effect of alteration and weathering on rock matrix porosity and on the available pore space, which affects diffusivity, are discussed. The main rock type in the crystalline bedrock of Syyry is a slightly foliated, gray tonalite with mica gneiss inclusions as well as minor, more mafic inclusions. The total porosity and the spatial porosity distribution and microstructure of the rocks were investigated using infiltration of carbon- 14-methylmethacrylate, electron microscopy and Hg-porosimetry. The laboratory-scale diffusion experiments were performed using (1) the out-leac…
Marine protected areas rescue a sexually selected trait in European lobster
2020
Abstract Marine protected areas (MPAs) are increasingly implemented worldwide to maintain and restore depleted populations. However, despite our knowledge on the myriad of positive responses to protection, there are few empirical studies on the ability to conserve species’ mating patterns and secondary sexual traits. In male European lobsters (Homarus gammarus), the size of claws relative to body size correlates positively with male mating success and is presumably under sexual selection. At the same time, an intensive trap fishery exerts selection against large claws in males. MPAs could therefore be expected to resolve these conflicting selective pressures and preserve males with large cl…
Automatic Take Off and Landing for UAS Flying in Turbulent Air - An EKF Based Procedure
2020
An innovative use of the Extended Kalman Filter (EKF) is proposed to perform automatic take off and landing by the rejection of disturbances due to turbulence. By using two simultaneously working Extended Kalman Filters, a procedure is implemented: the first filter, by using measurements gathered in turbulent air, estimates wind components; the second one, by using the estimated disturbances, obtains command laws that are able to reject disturbances. The fundamental innovation of such a procedure consists in the fact that the covariance matrices of process (Q) and measurement (R) noise are not treated as filter design parameters. In this way determined optimal values of the aforementioned m…
Lawsone derivatives target the Wnt/β-catenin signaling pathway in multidrug-resistant acute lymphoblastic leukemia cells.
2017
Abstract Multidrug resistance (MDR) represents a serious problem in cancer treatment. One strategy to overcome this obstacle is to identify agents that are selectively lethal to MDR cells. The aim of this study was to discover novel compounds against MDR leukemia and to determine the molecular mechanisms behind collateral sensitivity. A library of 1162 compounds was tested against parental, drug-sensitive CCRF-CEM cells using the resazurin assay. A total of 302 compounds showed reasonable activity (less than 50% cell viability). Eleven out of 30 lawsone derivatives revealed considerable collateral sensitivity in MDR P-glycoprotein (Pgp)-overexpressing CEM/ADR5000 cells. They reduced β-caten…
Ancient bacterial genomes reveal a high diversity of Treponema pallidum Strains in early Modern Europe
2020
Syphilis is a globally re-emerging disease, which has marked European history with a devastating epidemic at the end of the 15th century. Together with non-venereal treponemal diseases, like bejel and yaws, which are found today in subtropical and tropical regions, it currently poses a substantial health threat worldwide. The origins and spread of treponemal diseases remain unresolved, including syphilis’ potential introduction into Europe from the Americas. Here, we present the first genetic data from archaeological human remains reflecting a high diversity of Treponema pallidum in early modern Europe. Our study demonstrates that a variety of strains related to both venereal syphilis and y…
Drugs and diseases: Summary and consensus statements of group 1. The 5th EAO Consensus Conference 2018
2018
OBJECTIVES: The task of this working group was to update the knowledge about the use of drugs and biologicals affecting healing of soft tissue and bone during implant treatment or procedures associated with it. Moreover, the impact of titanium particles and biocorrosion on complications and implant survival has been analysed. MATERIALS AND METHODS: The literature in the areas of interest (platelet concentrates, antiresorptive drugs as well as implant-host interaction) was screened using systematic reviews for the former two areas, whereas a narrative critical review was performed for the latter topic. Two manuscripts on platelet concentrates, one manuscript on antiresorptive drugs and one m…
A Note on Laws of Motion for Aggregate Distributions
2020
I derive the law of motion for the aggregate distribution directly from the laws of motion for the individuals’ states. By relying on concepts from measure theory, the derivation is concise and intuitive. I address random shocks both at the micro level and at the macro level. Micro-level shocks completely cancel at the aggregate level provided that a law of large numbers applies. Therefore, the law of motion for the aggregate distribution is a deterministic process in the absence of macro-level uncertainty. If there are macro-level risks, the law of motion for the aggregate distribution exhibits a stochastic component additionally. I illustrate the formalism in a model of wealth accumulatio…
La incidencia de las malas relaciones entre los progenitores a la hora de acordar el régimen de guarda y custodia compartida. Análisis de la reciente…
2018
The relationship that the parents have with each other is one of the factors to take into consideration when adopting or not the modality of shared custody and custody after a situation of family crisis. To deny the shared modality if there was no good relationship between the parents was the rule until relatively recent dates. With the entry into force of local laws as well as the change in jurisprudence, the tendency that remains is to consider that it will no longer be enough that there is this bad relationship but will have to be a situation of high confrontation so that this situation may be grounds for denial of the shared custody regime.
Law and morals in the application of the public policy exception under the twin regulations 1103 and 1104 of 2016
2021
This paper discusses the interactions between fundamental principles of domestic legal systems and non-legal standards in the application of the public policy Generalklausel within the context of the twin Regulations 1103 and 1104 of 2016. In particular, this paper argues that public policy is composed of legal principles only and that there is no space for extra legal standards when the circulation of foreign deeds, decisions and laws is in discussion. This consideration has two consequences. Firstly, the role of good morals within contemporary private international law is extremely reduc