Search results for "AYA"

showing 10 items of 358 documents

Neuroblastoma after Childhood: Prognostic Relevance of Segmental Chromosome Aberrations, ATRX Protein Status, and Immune Cell Infiltration

2014

AbstractNeuroblastoma (NB) is a common malignancy in children but rarely occurs during adolescence or adulthood. This subgroup is characterized by an indolent disease course, almost uniformly fatal, yet little is known about the biologic characteristics. The aim of this study was to identify differential features regarding DNA copy number alterations, α-thalassemia/mental retardation syndrome X-linked (ATRX) protein expression, and the presence of tumor-associated inflammatory cells. Thirty-one NB patients older than 10 years who were included in the Spanish NB Registry were considered for the current study; seven young and middle-aged adult patients (range 18-60 years) formed part of the c…

MaleCancer ResearchHet heterogeneousGene ExpressionNeuroblastomaImmunophenotypingRegistriesYoung adultNeoplasm MetastasisMLPA multiplex ligation probe amplificationChildIn Situ Hybridization FluorescenceNuclear ProteinsMiddle AgedAYA adolescent and young adultsPrognosislcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogensNCA numerical chromosome aberrationImmunohistochemistryFemaleSCA segmental chromosome aberrationIHC immunohistochemistryNB neuroblastomaAdultX-linked Nuclear ProteinAdolescentaSNP single nucleotide polymorphism arrayBiologyMalignancyChromosome aberrationPolymorphism Single Nucleotidelcsh:RC254-282ArticleImmunophenotypingYoung AdultLymphocytes Tumor-InfiltratingNeuroblastomacnLOH copy-neutral loss of heterozygositymedicineHumansHom homogeneousATRXNeoplasm StagingChromosome AberrationsDNA Helicasesmedicine.diseaseSpainMNNA MYCN not amplifiedCancer researchFSCA focal segmental chromosome aberrationCD8MNA MYCN amplifiedNeoplasia
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The ependyma on the pineal of the guinea pig (Cavia cobaya)

1978

The proximal part of the epiphysis cerebri of the guinea pig is in close contact with the cerebrosopinal fluid of the third ventricle. A direct contact is not present as the pineal tissue is covered by a continuous ependymal layer. Two types of ependymal cells with different surface protrusions are discussed as being involved in possible interactions between the neuroendocrine tissue of the pineal organ and the cerebrospinal fluid. In addition, two different types of supraependymal structures are found on the ependymal surface of the habenulae and the wall of the third ventricle. Because of their morphological characteristics, these supraependymal structures are thought to be neural element…

MaleEmbryologyPathologymedicine.medical_specialtyEpendymal CellGuinea PigsBiologyPineal GlandCerebral VentriclesGuinea pigCerebrospinal fluidEpendymamedicineAnimalsClose contactThird ventricleEpiphysis cerebriCell BiologyAnatomymedicine.anatomical_structureMicroscopy Electron ScanningFemaleAnatomyEpendymaCavia cobayaDevelopmental BiologyAnatomy and Embryology
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A Scanning Technique to Measure Regional Cerebral Blood Flow and Oxyhemoglobin Level

2001

OBJECTIVE: The application of a laser scanning technique to measure regional cerebral blood flow (CBF) and tissue hemoglobin oxygenation (HbO 2 ) using the rat closed cranial window preparation is described. METHODS: Twenty-nine male Wistar rats were used to consecutively measure local CBF by laser Doppler flowmetry and tissue HbO 2 by a microspectrophotometric method at multiple corresponding cortical locations. The scanning technique used a computer-controlled micromanipulator. Data from three experimental models are presented: the whisker stimulation model, the ischemia-reperfusion model, and the sinus-vein thrombosis model. Sequential changes in local CBF and HbO 2 data before, during, …

MaleOptics and PhotonicsIschemiaHemodynamicsStimulationBrain IschemiaPhysical StimulationLaser-Doppler FlowmetrymedicineAnimalsSagittal Sinus ThrombosisRats WistarBalayagebusiness.industryBrainOxygenationLaser Doppler velocimetrymedicine.diseaseThrombosisRatsCerebral blood flowSpectrophotometryCerebrovascular CirculationOxyhemoglobinsReperfusion InjuryVibrissaeAnesthesiaSurgeryNeurology (clinical)businessBiomedical engineeringNeurosurgery
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Trends in the prevalence of asthma and allergic rhinitis in Italy between 1991 and 2010

2012

The prevalence of asthma increased worldwide until the 1990s, but since then there has been no clear temporal pattern. The present study aimed to assess time trends in the prevalence of current asthma, asthma-like symptoms and allergic rhinitis in Italian adults from 1990 to 2010. The same screening questionnaire was administered by mail or phone to random samples of the general population (age 20-44 yrs) in Italy, in the frame of three multicentre studies: the European Community Respiratory Health Survey (ECRHS) (1991-1993; n=6,031); the Italian Study on Asthma in Young Adults (ISAYA) (1998-2000; n=18,873); and the Gene Environment Interactions in Respiratory Diseases (GEIRD) study (2007-2…

MalePediatricsCross-sectional study95% CI 1.19-1.59) from 1998-2000 to 2007-2010but since then there has been no clear temporal pattern. The present study aimed to assess time trends in the prevalence of current asthmaAbstract The prevalence of asthma increased worldwide until the 1990stemporal trendsSurveys and QuestionnairesEpidemiologySurveys and QuestionnaireMedicineasthma-like symptoms and allergic rhinitis in Italian adults from 1990 to 2010. The same screening questionnaire was administered by mail or phone to random samples of the general population (age 20-44 yrs) in ItalyYoung adultrespectively. The prevalence of current asthma was stable during the 1990s and increased (relative risk 1.38from 10.1% to 13.9% and from 16.8% to 25.8%education.field_of_studyAllergic rhinitis; Asthma; Epidemiology; Prevalence; Temporal trends; Wheezing;medicine.diagnostic_testSmokingthe median prevalence of current asthmaallergic rhinitis asthma epidemiology prevalence temporal trends wheezingItalyAbstract The prevalence of asthma increased worldwide until the 1990s but since then there has been no clear temporal pattern. The present study aimed to assess time trends in the prevalence of current asthma asthma-like symptoms and allergic rhinitis in Italian adults from 1990 to 2010. The same screening questionnaire was administered by mail or phone to random samples of the general population (age 20-44 yrs) in Italy in the frame of three multicentre studies: the European Community Respiratory Health Survey (ECRHS) (1991-1993; n=6031); the Italian Study on Asthma in Young Adults (ISAYA) (1998-2000; n=18873); and the Gene Environment Interactions in Respiratory Diseases (GEIRD) study (2007-2010; n=10494). Time trends in prevalence were estimated using Poisson regression models in the centres that repeated the survey at different points in time. From 1991 to 2010 the median prevalence of current asthma wheezing and allergic rhinitis increased from 4.1% to 6.6% from 10.1% to 13.9% and from 16.8% to 25.8% respectively. The prevalence of current asthma was stable during the 1990s and increased (relative risk 1.38 95% CI 1.19-1.59) from 1998-2000 to 2007-2010 mainly in subjects who did not report allergic rhinitis. The prevalence of allergic rhinitis has increased continuously since 1991. The asthma epidemic is not over in Italy. During the past 20 yrs asthma prevalence has increased by 38% in parallel with a similar increase in asthma-like symptoms and allergic rhinitis.mainly in subjects who did not report allergic rhinitis. The prevalence of allergic rhinitis has increased continuously since 1991. The asthma epidemic is not over in Italy. During the past 20 yrssymbolsasthma prevalence has increased by 38%FemaleepidemiologyHumanPulmonary and Respiratory MedicineAdult494). Time trends in prevalence were estimated using Poisson regression models in the centres that repeated the survey at different points in time. From 1991 to 2010in parallel with a similar increase in asthma-like symptoms and allergic rhinitismedicine.medical_specialtyRhinitis Allergic PerennialPopulationprevalencethe Italian Study on Asthma in Young Adults (ISAYA) (1998-2000Settore MED/10 - Malattie Dell'Apparato Respiratorio031)and the Gene Environment Interactions in Respiratory Diseases (GEIRD) study (2007-2010Settore MED/01 - Statistica Medicasymbols.namesakeYoung AdultAllergic rhinitiHumansRespiratory soundsPoisson regressioneducationAsthmaRespiratory SoundsCross-Sectional Studieallergic rhinitisbusiness.industrywheezingwheezing and allergic rhinitis increased from 4.1% to 6.6%Rhinitis Allergic Seasonalasthmain the frame of three multicentre studies: the European Community Respiratory Health Survey (ECRHS) (1991-1993medicine.disease873)Cross-Sectional Studiesn=10Relative riskTemporal trendRespiratory Soundn=6n=18business
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A cervical myelopathy with a Hirayama disease-like phenotype

2008

A 21-year-old man with a muscular atrophy of the left distal upper extremity is presented. The disorder had been progressive over a few years, showing an exacerbation of the hand's weakness when the patient worked in a chilled environment (i.e., in a cold room). The patient's diagnostic work-up was extensive and the MRI documented the presence of a cervical myelopathy, associated to an inversion of the physiological lordosis at the C5-C6 level, with a phenotype highly resembling Hirayama disease. This case indirectly supports the debated hypothesis that juvenile amyotrophy of the upper limb (Hirayama disease) is actually a type of cervical myelopathy, with a likely ischaemic pathogenesis of…

Malemedicine.medical_specialtyWeaknessHIRAYAMANeurologyCumulative Trauma DisordersDermatologyFunctional LateralityMuscular Atrophy SpinalYoung AdultMyelopathyAtrophyIschemiaSpinal cord compressionNeural PathwaysmedicineHumansKyphosisMuscle SkeletalCervical myelopathy Hirayama disease Muscular atrophy MRIMuscle Weaknessbusiness.industryMuscle weaknessSyndromeGeneral MedicineAnatomyAmyotrophymedicine.diseaseMagnetic Resonance ImagingCold TemperatureOccupational DiseasesPsychiatry and Mental healthmedicine.anatomical_structureSpinal CordArmCervical VertebraeDisease ProgressionUpper limbSettore MED/26 - NeurologiaNeurology (clinical)medicine.symptombusinessSpinal Cord CompressionNeurological Sciences
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La traición en la amistad

2015

La traición en la amistad, la única obra teatral conservada de María de Zayas, es una historia de amor y de engaños entre hombres y mujeres, una historia que puede resultar a primera vista convencional, pero que tiene interés para los lectores modernos por ser abordada desde la perspectiva de la experiencia de una mujer, algo ciertamente poco habitual en el panorama del teatro del siglo XVII. Para esta edición crítica se ha utilizado el único testimonio que ha llegado hasta nosotros, el manuscrito conservado en la Biblioteca Nacional de España (signatura Res. 173), y se han tenido en cuenta diferentes ediciones modernas de la obra. El texto viene acompañado de diversas notas explicativas y …

María de ZayasSiglo de OroLiteratura españolaComediaTeatro del Siglo de OroLa traición en la amistadUNESCO::CIENCIAS DE LAS ARTES Y LAS LETRAS::Teoría análisis y crítica literarias::Crítica de textosSiglo XVII
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Polymeric carbon nitride (C3N4) as heterogeneous photocatalyst for selective oxidation of alcohols to aldehydes

2018

Abstract Polymeric carbon nitride (C3N4) is a semiconductor material which is a very promising green photocatalyst with good physico-chemical properties and stability. It is a metal-free carbon based non-toxic material which can be easily obtained from earth-abundant components. The robustness and versatility of C3N4 as a photo-redox catalyst allows its use for selective oxidations by heterogeneous photocatalysis. This paper reviews the state of art in the application of C3N4 as heterogeneous photocatalyst for selective oxidation of alcohols to the corresponding aldehydes.

Materials scienceCarbon nitrideSemiconductor materialsPartial oxidationchemistry.chemical_element02 engineering and technology010402 general chemistry01 natural sciencesC3N4CatalysisCatalysischemistry.chemical_compoundCarbon nitridePolymeric photocatalyst2D-materialGeneral Chemistry021001 nanoscience & nanotechnologySelective photo-oxidation0104 chemical scienceschemistryChemical engineeringSettore CHIM/03 - Chimica Generale E InorganicaAlcohol oxidationState of artPhotocatalysisSettore CHIM/07 - Fondamenti Chimici Delle Tecnologie0210 nano-technologyAlcoholCarbonPhotocayalysi
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Iron Mineralogy of Venus' Surface Investigated by M�ssbauer Spectroscopy

2000

Abstract We discuss the use of Mossbauer (MB) spectroscopy to study Fe-bearing minerals on Venus' surface. At present, there is no direct information about the mineralogy of Venus' surface, although in situ chemical analyses by X-ray fluorescence (XRF) spectroscopy have been done by the Venera 13, 14, and Vega 2 spacecraft at three landing sites. The XRF elemental analyses are sensitive to major rock-forming elements heavier than sodium and show the presence of several mass percent iron. Normative mineralogical calculations model the Fe mineralogy at the Venera 13, 14, and Vega 2 landing sites, but the actual Fe minerals present are unknown. We calculate synthetic MB spectra for the normati…

Materials sciencebiologyMineralogyAstronomy and AstrophysicsVenusHematiteengineering.materialbiology.organism_classificationchemistry.chemical_compoundchemistrySpace and Planetary Sciencevisual_artMössbauer spectroscopyvisual_art.visual_art_mediumengineeringFayalitePyriteSpectroscopyPyrrhotiteMagnetiteIcarus
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Characterization of Maya Blue Pigment in Pre-Classic and Classic Monumental Architecture of the Ancient Pre-Culombian City of Calakmul (Campeche, Mex…

2011

This paper presents the first evidence of the use of Maya Blue pigment in late pre-classic (c.300BC-300AD) architecture in the Maya Lowlands. This was detected combining an innovative technique, the voltammetry of microparticles (VMP), with atomic force microscopy (AFM), transmission electron microscopy (TEM), scanning electron microscopy/energy dispersive X-ray microanalysis (SEM/EDX), visible spectrophotometry and Fourier transform infrared spectroscopy (FTIR). The pigment was found on the polychrome facade of substructure IIC of pre-Columbian city of Calakmul (Campeche, Mexico). The identification of Maya Blue in this building may prove to be the earliest known use of this colour on the …

Maya BlueArcheologyAtomic force microscopyMaterials Science (miscellaneous)media_common.quotation_subjectCalakmulAncient pigmentsConservationArtArchaeologyPigmentPre-Columbian artChemistry (miscellaneous)visual_artPINTURAvisual_art.visual_art_mediumMaya muaral paintingMayaPolychromeGeneral Economics Econometrics and FinanceAnalytical chemistrySpectroscopymedia_common
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‘Maya chemistry’ of organic–inorganic hybrid materials: isomerization, cyclicization and redox tuning of organic dyes attached to porous silicates

2013

[EN] Association of indigo and lapachol dyes to aluminosilicate clays yields polyfunctional organic – inorganic hybrid materials forming Maya Blue-like systems. Upon partial removing of clay's zeolitic water by moderate thermal treatment, abundant isomerization, cyclicization and oxidation reactions occur defining a‘ Maya chemistry whose complexity could explain the versatile use of such materials in the pre-Columbian cultures and permits the preparation of polyfunctional materials potentially usable for therapeutic and catalytic purposes.

Maya BlueChemistryGeneral Chemical EngineeringGeneral ChemistryThermal treatmentRedoxIndigoCatalysisAluminosilicatePINTURAMaya chemistryOrganic chemistryPorosityHybrid materialIsomerizationRSC Advances
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