Search results for "Absolute risk"

showing 3 items of 73 documents

274 Comparative analysis of patients with acute coronary and cerebrovascular syndromes from the national French hospitalisation heath care system dat…

2011

Objective To compare vascular risk factor profiles and early outcomes in all French patients hospitalized for either acute coronary (ACS), or cerebrovascular syndromes (CVS), or both, between 2005 and 2008. Setting All French hospitals. Design Retrospective analysis. Data sources National database called “Hospital Discharge Diagnosis Records”. Main outcomes measured Number and annual rates, vascular risk factors, and early outcome of hospitalized patients for a unique stay for ACS or CVS or for both ACV and CVS in a 2-month time window. Results Over the 4-year study-period, 1,189,043 patients were hospitalized for CVS and/or ACS. Among these, 638,061 (53.7%) had CVS alone, 525,419 (44.3%) h…

medicine.medical_specialtybusiness.industryAbsolute risk reductionEarly deathAtrial fibrillationVascular riskmedicine.diseaseTime windowsDiabetes mellitusInternal medicineHospital dischargemedicineNational databasebusinessCardiology and Cardiovascular MedicineArchives of Cardiovascular Diseases Supplements
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Home treatment of fragile patients with acute pulmonary embolism: a subgroup analysis of the multinational home treatment of pulmonary embolism (HoT-…

2020

Abstract Background and aims Subgroup analyses of randomized trials and cohort studies on direct oral anticoagulants (DOACs) suggested that single direct drug treatment may be effective and safe in elderly and “fragile” patients with acute pulmonary embolism (PE). In a post-hoc analysis of HoT-PE, a prospective multicenter management trial, we studied whether early discharge and home treatment of acute PE is effective and safe in these patients. Methods HoT-PE enrolled patients with acute PE classified as being at low risk based on the modified Hestia criteria and the absence of right ventricular dysfunction. The primary efficacy outcome was symptomatic recurrent VTE, or PE-related death wi…

medicine.medical_specialtybusiness.industryAbsolute risk reductionRenal functionSubgroup analysismedicine.diseasePulmonary embolismPharmacotherapyInternal medicineCardiologyMedicineHome treatmentCardiology and Cardiovascular MedicinebusinessVenous thromboembolismEuropean Heart Journal
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Delayed versus early initiation of renal replacement therapy for severe acute kidney injury: a systematic review and individual patient data meta-ana…

2020

Summary Background The timing of renal replacement therapy (RRT) for severe acute kidney injury is highly debated when no life-threatening complications are present. We assessed whether a strategy of delayed versus early RRT initiation affects 28-day survival in critically ill adults with severe acute kidney injury. Methods In this systematic review and individual patient data meta-analysis, we searched MEDLINE (via PubMed), Embase, and the Cochrane Central Register of Controlled Trials for randomised trials published from April 1, 2008, to Dec 20, 2019, that compared delayed and early RRT initiation strategies in patients with severe acute kidney injury. Trials were eligible for inclusion …

medicine.medical_specialtybusiness.industrymedicine.medical_treatmentAbsolute risk reductionAcute kidney injuryGeneral Medicine030204 cardiovascular system & hematologyurologic and male genital diseasesmedicine.diseaseClinical trial03 medical and health sciences0302 clinical medicineInternal medicineRelative riskMeta-analysisSeverity of illnessmedicine030212 general & internal medicineRenal replacement therapybusinessKidney diseaseThe Lancet
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