Search results for "Active components"

showing 3 items of 13 documents

1H-naphtho[2,1-b]thiete and 2H-naphtho[2,3-b]thiete- synthesis and reactivity

1994

Abstract The title compounds 4 and 8 are obtained by flash vacuum pyrolysis of the corresponding hydroxymethylthionaphthols 3 and 7. Whereas 4 shows a smooth ring opening on heating, 8 is thermally stable but reacts photochemically. The different behavior is explained on the basis of an MNDO calculation. The valence isomers 4′ and 8′ represent thioquinonemethides, which are highly reactive components in [12π + 2π]cycloaddition processes (4 → 9, 10, 11; 8 → 12).

Valence (chemistry)Flash vacuum pyrolysisChemistryStereochemistryOrganic ChemistryDrug DiscoverySous videMNDOReactive componentsReactivity (chemistry)BiochemistryMedicinal chemistryCycloadditionTetrahedron Letters
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ChemInform Abstract: 1H-Naphtho(2,1-b)thiete and 2H-Naphtho(2,3-b)thiete - Synthesis and Reactivity.

2010

Abstract The title compounds 4 and 8 are obtained by flash vacuum pyrolysis of the corresponding hydroxymethylthionaphthols 3 and 7. Whereas 4 shows a smooth ring opening on heating, 8 is thermally stable but reacts photochemically. The different behavior is explained on the basis of an MNDO calculation. The valence isomers 4′ and 8′ represent thioquinonemethides, which are highly reactive components in [12π + 2π]cycloaddition processes (4 → 9, 10, 11; 8 → 12).

Valence (chemistry)Flash vacuum pyrolysisComputational chemistryChemistryMNDOReactivity (chemistry)Reactive componentsGeneral MedicineRing (chemistry)CycloadditionChemInform
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Forderungen und Erwartungen an einen optimalen Volumenersatz

2005

A volume replacement should compensate a reduction in the intravascular volume and counteract a hypovolemia so that hemodynamics and vital functions can be maintained. For this therapy, a physiologically-based solution comprising both osmotically and colloid osmotically active components should be administered. A consensus is proposed for this purpose which takes into consideration the following aspects: The optimum colloid, the questionable use of albumin, the physiological electrolyte pattern encompassing sodium, potassium, chloride and phosphate and their contributions to osmolality, an eventual addition of glucose, the physiological acid-base status with bicarbonate or alternately with …

medicine.medical_specialtyBicarbonateVolume replacementActive componentsBlood volumeGeneral MedicineElectrolyteCritical Care and Intensive Care MedicineSurgerychemistry.chemical_compoundAnesthesiology and Pain MedicinechemistryHypovolemiaEmergency MedicinemedicineIntravascular volume statusmedicine.symptomIntensive care medicineains · Anästhesiologie · Intensivmedizin · Notfallmedizin · Schmerztherapie
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