Search results for "Activity"
showing 10 items of 7178 documents
Terminal tendon cell differentiation requires the glide/gcm complex.
2004
International audience; Locomotion relies on stable attachment of muscle fibres to their target sites, a process that allows for muscle contraction to generate movement. Here, we show that glide/gcm and glide2/gcm2, the fly glial cell determinants, are expressed in a subpopulation of embryonic tendon cells and required for their terminal differentiation. By using loss-of-function approaches, we show that in the absence of both genes, muscle attachment to tendon cells is altered, even though the molecular cascade induced by stripe, the tendon cell determinant, is normal. Moreover, we show that glide/gcm activates a new tendon cell gene independently of stripe. Finally, we show that segment p…
Rbt1 Protein Domains Analysis in Candida albicans Brings Insights into Hyphal Surface Modifications and Rbt1 Potential Role during Adhesion and Biofi…
2013
Cell wall proteins are central to the virulence of Candida albicans. Hwp1, Hwp2 and Rbt1 form a family of hypha-associated cell surface proteins. Hwp1 and Hwp2 have been involved in adhesion and other virulence traits but Rbt1 is still poorly characterized. To assess the role of Rbt1 in the interaction of C. albicans with biotic and abiotic surfaces independently of its morphological state, heterologous expression and promoter swap strategies were applied. The N-terminal domain with features typical of the Flo11 superfamily was found to be essential for adhesiveness to polystyrene through an increase in cell surface hydrophobicity. A 42 amino acid-long domain localized in the central part o…
Human capital and RD Driven Growth: analyse for France at regional level on the long run
2012
At the root of the Lisbon goal, for Europe, is placed the awareness for advocating a close link between growth and dissemination of advanced knowledge and innovation, on the one hand, and raising in general endowments in human capital, on the other hand, as to have power over the development of non-specific skills and boost efficiency. Much work in literature also stressed the interest of the position concerning traditional activities in the geography of innovation and links, in the long term, between the spatial distribution of longestablished skills and knowledge creation. Following Jones, in this approach, for which contribution to R&D and innovation explains half of the increase in weal…
Analysis of virtual helps usage in a virtual environment for learning
2007
Study of relationships between the structure of aroma compounds and their retention-release between vapour phase and dairy gels
2010
An integrated approach physicochemistry and structures activity relationships has been carried out to study the aroma compounds retention-release phenomenon in a fat free dairy gel added with pectin. This study aimed to identify the molecular properties that govern this phenomenon assuming that modifying the structure leads automatically to a change in the retention-release of aroma compounds. For this purpose, we have determined the partition coefficients of 28 aroma compounds in water, in pectin gels and in dairy gels supplemented or not supplemented with pectin, at equilibrium conditions using the PRV method (Phase Ratio Variation). Then, we have performed a structure-retention relations…
Different a-casein association states and their interaction with lipid vesicles to study antibacterial activity
The interactions between caseins and lipid membranes are fundamental for the physiological function of these proteins. Moreover, the understanding of the underlying molecular mechanisms is of great interest for the development of new casein derived antimicrobial peptides. Indeed, it was already shown that peptides derived from caseins possess antibacterial activity but their mechanisms of action is still debated. Here, we present an experimental study on the interaction between model lipid membranes and a-casein by means of spectroscopy and fluorescence microscopy techniques. a-casein is an unfolded protein that due to its amphiphilic nature is known to self-assembly into non-stable micella…
Accelerometer-based osteogenic indices, moderate-to-vigorous and vigorous physical activity, and bone traits in adolescents
2022
Objectives: We investigated the associations of accelerometry-derived osteogenic indices (OIs), moderate-to-vigorous (MVPA), and vigorous intensity physical activity (VPA) with peripheral quantitative computed tomography (pCQT) parameters in 99 adolescents aged 10–13 years. Methods: Bone parameters were assessed at the distal (4%) and shaft (66%) of the tibia using pQCT. Accelerometers were worn on the right hip for 7 consecutive days. OIs were calculated based on acceleration peak histograms either using all of the peaks (OI) or peaks with acceleration ≥5.2 g (HOI). MVPA and VPA were defined using previously published cut-points. Results: HOI was positively associated with total area (Part…
Relationship between occupational and leisure-time physical activity and the need for recovery after work
2023
Abstract Background Health benefits of physical activity are very well acknowledged but the role of both occupational physical activity (OPA) and leisure time physical activity (LTPA) in recovery after work is not thoroughly understood. The purpose of this study was to investigate the association between accelerometer-measured OPA and LTPA and the need for recovery after work (NFR) in early childhood education and care (ECEC) professionals. Methods The study participants were 217 female ECEC professionals aged 17–64. Physical activity was recorded with a three-axis accelerometer (ActiGraph GT9X Link, ActiGraph, USA) for seven consecutive days. Separate analyses were conducted for both OPA a…
Physical activity and sedentary time during physical education lessons between different physical activity groups of a sample of finnish 11-year-old …
2019
Problem statement: Insufficient PA is rising concern in modern society. Physical education as a compulsory subject allows all students to engage physical activity. However, the activity levels may vary during the physical education lesson depending on the motivation of students. Purpose: The purpose of this study was to determine the amount of time spent in light physical activity, moderate to vigorous physical activity and sedentary activity by a sample of Finnish fifth grade students during physical education lessons. Approach: A cohort of 407 Finnish students' (177 boys, 232 girls) participated to study. To determine activity, participants wore GTX3 Actigraphs for seven consecutive days.…