Search results for "Activity"

Brain Functional Effects of Psychopharmacological Treatment in Major Depression: A Focus on Neural Circuitry of Affective Processing

2015

In the last two decades, neuroimaging research has reached a much deeper understanding of the neurobiological underpinnings of major depression (MD) and has converged on functional alterations in limbic and prefrontal neural networks, which are mainly linked to altered emotional processing observed in MD patients. To date, a considerable number of studies have sought to investigate how these neural networks change with pharmacological antidepressant treatment. In the current review, we therefore discuss results from a) pharmacological functional magnetic resonance imaging (fMRI) studies investigating the effects of selective serotonin or noradrenalin reuptake inhibitors on neural activation…

Bright spots in the darkness of cancer: A review of starfishes-derived compounds and their anti-tumor action

2019

The fight against cancer represents a great challenge for researchers and, for this reason, the search for new promising drugs to improve cancer treatments has become inevitable. Oceans, due to their wide diversity of marine species and environmental conditions have proven to be precious sources of potential natural drugs with active properties. As an example, in this context several studies performed on sponges, tunicates, mollusks, and soft corals have brought evidence of the interesting biological activities of the molecules derived from these species. Also, echinoderms constitute an important phylum, whose members produce a huge number of compounds with diverse biological activities. In…

Marketing-as-practice : A framework and research agenda for value-creating marketing activity

2023

This paper draws on practice theory and a review of practice theoretical studies in marketing, management, consumer, and markets research to advance our knowledge of marketing as a value-creating activity within firms. Building on previous research, the paper contributes to the literature by advancing a Marketing-as-Practice (MAP) framework based on three key concepts: marketing practices, marketing practitioners, and marketing praxis. The structures and interrelationships between these key concepts are also outlined. The framework can be used to study value-creating marketing activities within firms as well as between firms and their stakeholders which is in line with the American Marketin…

Depressive symptoms, sense of coherence, physical activity and genetic factors among older people

2012

Does level of leisure time physical activity, in a sample of patients with depression, predict health care utilization over a subsequent 5-year perio…

2018

Objectives: The main aim of this study was to investigate the association between leisure time physical activity (LTPA) and health care utilization (HCU) and furthermore, socio-demographic and clinical factors according to LTPA level among depressed patients based on data drawn from the Finnish Depression and Metabolic Syndrome in Adults (FDMSA)-study (2009-2016). Methods: 447 depressed patients aged 35-65 from municipalities within the Central Finland Hospital District participated in this study. Depressive symptoms (DS) were determined with the Beck Depression Inventory (a 10 points) and the psychiatric diagnosis confirmed with a diagnostic interview (M.I.N.I.). Severity of depression was…

Fyysinen aktiivisuus, harrastustoiminta ja liikkumiskyky iäkkäiden ihmisten psyykkisen hyvinvoinnin ennustajina : 65-84-vuotiaiden jyväskyläläisten 8…

2004

Päivi Lampinen selvitti fyysisen aktiivisuuden, harrastustoiminnan ja liikkumiskyvyn yhteyksiä 65–84-vuotiaiden jyväskyläläisten kotona asuvien miesten ja naisten psyykkiseen hyvinvointiin kahdeksan vuoden seuruututkimuksen aikana. Lisäksi hän tutki näiden tekijöiden ja niiden välisten yhteyksien taustalla olevia tekijöitä, kuten kroonisia sairauksia, päivittäistä toimintakykyä ja sosiodemografisia tekijöitä. The purpose of this prospective study was to examine the roles of activity and mobility status as associates and predictors of mental well-being among older adults over an 8-year period. In addition, the aim was to explore the individual-related factors underlying the associations betw…

Interrelationships of physical activity and depressive symptoms with cardiometabolic risk factors

2013

Alterations in working memory maintenance of fearful face distractors in depressed participants : An ERP study

2023

Task-irrelevant threatening faces (e.g., fearful) are difficult to filter from visual working memory (VWM), but the difficulty in filtering non-threatening negative faces (e.g., sad) is not known. Depressive symptoms could also potentially affect the ability to filter different emotional faces. We tested the filtering of task-irrelevant sad and fearful faces by depressed and control participants performing a color-change detection task. The VWM storage of distractors was indicated by contralateral delay activity, a specific event-related potential index for the number of objects stored in VWM during the maintenance phase. The control group did not store sad face distractors, but they automa…

Non-melancholic depressive symptoms are associated with above average fat mass index in the Helsinki birth cohort study

2022

AbstractThere is an existing link between two of the most common diseases, obesity and depression. These are both of great public health concern, but little is known about the relationships between the subtypes of these conditions. We hypothesized that non-melancholic depressive symptoms have a stronger relationship with both body composition (lean mass and fat mass) and dysfunctional glucose metabolism than melancholic depression. For this cross-sectional study 1510 participants from the Helsinki Birth Cohort Study had their body composition evaluated as lean mass and fat mass (Lean Mass Index [LMI, kg/m2] + Fat Mass Index [FMI kg/m2] = Body Mass Index). Participants were evaluated for dep…

Social engagement, mood, and mortality in old age

2017

Social relationships, social activity, and experiencing fulfilment of interpersonal needs are essential aspects of well-being in older people. The purpose of this research was twofold: first, to investigate the associations of various dimensions of social activity and perceived togetherness with indicators of health decline; and second, to identify potential mediators in these associations. This dissertation is based on data from two research projects. The first, the Evergreen project, is a multidisciplinary, longitudinal follow-up study on the health and functional capacity of people aged 65–84 in 1988 (n=1 181) resident in Jyväskylä, Finland. Data on institutionalization and mortality wer…