Search results for "Activity"

Perceptions about physical activity and its associated benefits among employees : case study in 12 Multinational Companies in Pakistan

2016

This thesis focus on the perceptions of the employees working in Multinational Corporations (MNCs) in Pakistan, with regards to their physical activity and its associated benefits. Previous research has shown that physical activity is positively associated with on-job productivity and life satisfaction of the employees across the world. With no such research being carried out in Pakistan before, this thesis aims to focus on the same factors, but uses employees’ perceptions rather than employing an intervention study. Furthermore associated benefits of physical activity such as reduced healthcare cost, decrease in exposure to various heath-risks and reduced presenteeism were also addressed w…

Effects of resistance training frequency on muscle strength, activity and mass during a 24-week intervention in the elderly

2016

Elderly populations are increasingly affected by sarcopenia, dynapenia and osteoporosis. They all increase frailty and decrease quality of life and life-expectancy. Resistance training (RT) has been reported extensively as a tool that can prevent, counter and in some cases reverse the course of the abovementioned diseases. Several studies covering RT adaptations in elderly populations have investigated periods between 6 up to 88 weeks with different frequencies, from 1 to 3 trainings / week and a wide range of intensities (30-85% or one repetition maximum) and different volumes. The aim of this study was to investigate the effect of different training frequencies (one, two or three times / …

Do Running and Strength Exercises Reduce Daily Muscle Inactivity Time?

2016

Understanding how a specific exercise changes daily activity patterns is important when designing physical activity interventions. We examined the effects of strength and interval running exercise sessions on daily activity patterns using recordings of quadriceps and hamstring muscle electromyographic (EMG) activity and inactivity. Five male and five female subjects taking part in a 10-week training programme containing both strength and interval running training sessions were measured for daily muscle EMG activities during three days: on a strength day, an interval running day, and a day without exercise. EMG was measured using textile electrodes embedded into sport shorts that were worn 9…

Myostatin/activin blocking combined with exercise reconditions skeletal muscle expression profile of mdx mice

2015

Duchenne Muscular Dystrophy is characterized by muscle wasting and decreased aerobic metabolism. Exercise and blocking of myostatin/activin signaling may independently or combined counteract muscle wasting and dystrophies. The effects of myostatin/activin blocking using soluble activin receptor-Fc (sActRIIB-Fc) administration and wheel running were tested alone or in combination for seven weeks in dystrophic mdx mice. Expression microarray analysis revealed decreased aerobic metabolism in the gastrocnemius muscle of mdx mice compared to healthy mice. This was not due to reduced home-cage physical activity, and was further downregulated upon sActRIIB-Fc treatment in enlarged muscles. However…

Derepressing muscleblind expression by miRNA sponges ameliorates myotonic dystrophy-like phenotypes in Drosophila

2016

AbstractMyotonic Dystrophy type 1 (DM1) originates from alleles of the DMPK gene with hundreds of extra CTG repeats in the 3′ untranslated region (3′ UTR). CUG repeat RNAs accumulate in foci that sequester Muscleblind-like (MBNL) proteins away from their functional target transcripts. Endogenous upregulation of MBNL proteins is, thus, a potential therapeutic approach to DM1. Here we identify two miRNAs, dme-miR-277 and dme-miR-304, that differentially regulate muscleblind RNA isoforms in miRNA sensor constructs. We also show that their sequestration by sponge constructs derepresses endogenous muscleblind not only in a wild type background but also in a DM1 Drosophila model expressing non-co…

Maximal Strength Training as a Therapeutic Approach in Long-Standing Anorexia Nervosa: A Case Study of a Woman With Osteopenia, Menstrual Dysfunction…

2018

In persons with anorexia nervosa (AN), compulsive exercise and osteopenia are common symptoms. Although treatment of osteopenia besides weight regain is lacking, maximal strength training (MST) has been found to be effective in other populations. Such training has not been prescribed to those with AN due to uncertainty of tolerance. We therefore examined use of MST in a woman with long-standing AN, osteopenia, menstrual dysfunction, and compulsive exercise. The MST intervention consisted of four exercises: three sets of five repetitions maximum (RM), 3 times per week for 16 weeks. We examined muscle strength, bone mineral density (BMD), AN psychopathology, and compulsive exercise at baseli…

Influence of physical activity and maturation status on bone mass and geometry in early pubertal girls1

2005

This study aimed to evaluate the influence of leisure-time physical activity on the development of bone mass and density in early pubertal girls. Scores of physical activity were obtained from 242 Finnish girls (10-12 years old within Tanner Stages I-II) using a questionnaire. Bone mass and density were assessed using different densitometric techniques. At Tanner Stage I, active girls had significantly higher bone mineral mass (BMC) and areal bone mineral density (aBMD) of the whole body and cortical volumetric BMD and thickness of the tibial shaft compared with sedentary girls (P<0.05). On the other hand, the active girls at Tanner Stage II showed significantly higher values only in BMC an…

Estrogen metabolism modulates bone density in men.

2007

Estrogen is a critical hormone for bone homeostasis in men, but no information is available on the role of estrogen metabolism among men. The aim of this study was to evaluate the effect of estrogen hydroxylation on male bone mineral density (BMD). Participants consisted of 61 healthy Caucasian males (mean age 66.6 +/- 1.0 years). Urinary estrogen metabolites were measured by enzyme-linked immunosorbent assay, serum estradiol by ultrasensitive radioimmunoassay, sex hormone binding globulin by radioimmunoassay, and BMD of the lumbar spine and the proximal femur by dual-energy X-ray absorptiometry. Active estrogen metabolites, 16alpha-hydroxyestrone (16alphaOHE(1)) and estriol (E(3)), positiv…

2020

(1) Background: Assessments of intervertebral disc (IVD) changes, and IVD tissue adaptations due to physical activity, for example, remains challenging. Newer magnetic resonance imaging techniques can quantify detailed features of the IVD, where T2-mapping and T2-weighted (T2w) and Dixon imaging are potential candidates. Yet, their relative utility has not been examined. The performances of these techniques were investigated to characterize IVD differences in asymptomatic individuals with distinct physical activity histories. (2) Methods: In total, 101 participants (54 women) aged 25–35 years with distinct physical activity histories but without histories of spinal disease were included. T1…

Fysioterapeuters erfaringer med bruk av fysisk aktivitet til eldre deprimerte

2015

This article is based upon a study of the experiences of physiotherapists working with elderly depressed patients and the use of physical activity. Depression in the elderly is a common condition, and it is estimated to be the second most common cause of failing health towards 2020. Physical activity has a positive effect on depression in the elderly. The aim of this study was to investigate the experiences of physiotherapist`s in the treatment of elderly depressed patients over 65 years of age. Data was collected by qualitative reasearch interviews of 5 physiotherapists. Important findings of this study were that the physiotherapists experienced that they did not get any referrals to treat…