Search results for "Adaptive"
showing 10 items of 792 documents
The Human Mammary Odour Factor: Variability and Regularities in Sources and Functions
2019
In the course of evolution, human mothers have been, and still are, under strong selective pressure to induce their newborns’ colostrum ingestion promptly after birth. As a concentrate of nutrients, passive immunity, antioxidants, growth factors and symbiotic microbiota, colostrum functions as the evolved antidote to ubiquitous pathogens and threats of neonatal exhaustion. Under such constraints, any means to speed up colostrum/milk intake can only have been beneficial to neonatal viability and adaptive life onset along evolutionary time. The areolar-nipple areas of human lactating females emit lacteal substrates conveying chemostimuli that are attractive and release mouthing and sucking in…
Experimental study on the effects of physical training on the defibrillation threshold
2011
Background: Chest compression artifacts during cardiopulmonary resuscitation (CPR) deteriorate the rhythm diagnosis of automated external defibrillators (AED). Cardiopulmonary resuscitation must therefore be interrupted for a reliable shock/no-shock decision. However, these hands-off intervals adversely affect the defibrillation success, and, in addition, pauses in chest compressions compromise circulation. An accurate diagnosis of the rhythmwhile performing CPR is therefore needed to minimize these hands-off intervals. Methods: The characteristics of the CPR artifact are very variable, and the artifact presents an important spectral overlap with human cardiac arrest rhythms. Consequently, …
The crisis of psychiatry – insights and prospects from evolutionary theory
2012
Darwin’s emphasis on natural selection has had a transformative influence on how biological and medical sciences are conceptualized and conducted. However, the relevance of his ideas for the understanding of psychiatric conditions is still under-appreciated. Modern understanding of disease has required appreciation of the dialectical give and take between environmental influences, life history theory imperatives, human behavioral ecology, and characteristics of adaptive processes at all levels of the individual. This has enabled a better comprehension of metabolic disturbances, cancers, auto-immune disease, inherited anemias, and vulnerability to infectious disease 1. Here we propose that a…
A fully automatic 2D segmentation method for uterine fibroid in MRgFUS treatment evaluation
2015
PurposeMagnetic Resonance guided Focused UltraSound (MRgFUS) represents a non-invasive surgical approach that uses thermal ablation to treat uterine fibroids. After the MRgFUS treatment, an operator must manually segment the treated fibroid areas to evaluate the NonPerfused Volume (NPV). This manual approach is operator-dependent, introducing issues of result reproducibility, which could lead to errors in the subsequent follow-up phase. Moreover, manual segmentation is time-consuming, and can have a negative impact on the optimization of both machine-time and operator-time. MethodTo address these issues, in this paper a novel fully automatic method based on the unsupervised Fuzzy C-Means cl…
Off-line control of the postprandial glycemia in type 1 diabetes patients by a fuzzy logic decision support
2012
The target of this paper is to describe the use of fuzzy techniques in the development of a decision support system that allows the optimization of postprandial glycemia in type 1 diabetes patients taking into account the kind of meal taken by patients, the preprandial glycemia and the insulin resistance (the response of the body to insulin dose injection therapy). The decision support system can, in many cases, provide patients with the correct number of rapid insulin units that must be assumed to assure an optimal glycemic profile, keeping the blood glucose level close to the homeostatic condition, several hours after the meal.
Proceedings of the Eighth Annual Deep Brain Stimulation Think Tank: Advances in Optogenetics, Ethical Issues Affecting DBS Research, Neuromodulatory …
2021
We estimate that 208,000 deep brain stimulation (DBS) devices have been implanted to address neurological and neuropsychiatric disorders worldwide. DBS Think Tank presenters pooled data and determined that DBS expanded in its scope and has been applied to multiple brain disorders in an effort to modulate neural circuitry. The DBS Think Tank was founded in 2012 providing a space where clinicians, engineers, researchers from industry and academia discuss current and emerging DBS technologies and logistical and ethical issues facing the field. The emphasis is on cutting edge research and collaboration aimed to advance the DBS field. The Eighth Annual DBS Think Tank was held virtually on Septem…
Bonnes pratiques de radiothérapie guidée par l’image
2015
Image-guided radiotherapy (IGRT) aims to take into account the anatomical variations occurring during the course of radiotherapy, by direct or indirect visualization of the target volume followed by a corrective action. The movements of the target, or at least the set-up errors are corrected by moving the treatment table, corresponding to the simplest and most validated IGRT modality in a standard practice. The deformations of the target volume and organs at risk are however much more common, and unfortunately much more complicated to consider, requiring multiple planning before or during the treatment, corresponding to the adaptive radiotherapy strategies. The planning target volume must b…
Advanced technologies for detecting tremor in Parkinson's disease.
2019
Objective Accurate and reliable detection of tremor onset in Parkinson’s disease (PD) is critical to the success of adaptive deep brain stimulation (aDBS) therapy. Here, we investigated the potential use of feature engineering and machine learning methods for more accurate detection of rest tremor in PD. Methods We analyzed the local field potential (LFP) recordings from the subthalamic nucleus region in 12 patients with PD (16 recordings). To explore the optimal biomarkers and the best performing classifier, the performance of state-of-the-art machine learning (ML) algorithms and various features of the subthalamic LFPs were compared. We further used a Kalman filtering technique in feature…
Cardiorespiratory Coordination after Training and Detraining. A Principal Component Analysis Approach
2016
Our purpose was to study the effects of different training modalities and detraining on cardiorespiratory coordination (CRC). Thirty-two young males were randomly assigned to four training groups: aerobic (AT), resistance (RT), aerobic plus resistance (AT + RT), and control (C). They were assessed before training, after training (6 weeks) and after detraining (3 weeks) by means of a graded maximal test. A principal component (PC) analysis of selected cardiovascular and cardiorespiratory variables was performed to evaluate CRC. The first PC (PC1) coefficient of congruence in the three conditions (before training, after training and after detraining) was compared between groups. Two PCs were …
High-resolution images in macular disorders
2021
Objective: This study analyzed and compared the results of adaptive optics (AO) and fundus autofluorescence (FAF) in various maculopathies. Methods: The study included four different types of maculopathy: central serous chorioretinopathy (CSC), retinitis pigmentosa (RP), Stargardt disease (STGD) and phototoxic retinopathy. In all four cases, cone mosaic and cone density were obtained using AO fundus camera. Further, the high-resolution images were compared with the FAF and optical coherence tomography (OCT) results. Results: In CSC, FAF and AO, changes could be shown in the macula even two years after the subretinal fluid resorption, as opposed to a normal OCT. The improvement of FAF and co…