Search results for "Adhesion"

The influence of bone allograft processing on osteoblast attachment and function

2004

In order to assess the influence of eight different sterilisation and disinfection methods for bone allografts on adhesion, proliferation, and differentiation of human bone marrow stromal cells (BMSC), cells were grown in culture and then plated onto pieces of human bone allografts. Following processing methods were tested: autoclavation (AUT), low-temperature-plasma sterilisation of demineralised allografts (D-LTP), ethylene oxide sterilisation (EtO), fresh frozen bone (FFB), 80 degrees C-thermodisinfection (80 degrees C), gamma-irradiation (Gamma), chemical solvent disinfection (CSD), and Barrycidal-disinfection (BAR). The seeding efficiency was determined after one hour to detect the num…

Long Non Coding RNA H19: A New Player in Hypoxia-Induced Multiple Myeloma Cell Dissemination

2019

The long non-coding RNA H19 (lncH19) is broadly transcribed in the first stage of development and silenced in most cells of an adult organism

Biomaterials coated by dental pulp cells as substrate for neural stem cell differentiation

2011

[EN] This study is focused on the development of an in vitro hybrid system, consisting in a polymeric biomaterial covered by a dental pulp cellular stroma that acts as a scaffold offering a neurotrophic support for the subsequent survival and differentiation of neural stem Cells. In the first place, the behavior of dental pulp stroma on the polymeric biomaterial based on ethyl acrylate and hydroxy ethyl acrylate copolymer was studied. For this purpose, cells from normal human third molars were grown onto 0.5-mm-diameter biomaterial discs. After cell culture, quantification of neurotrophic factors generated by the stromal cells was performed by means of an ELISA assay. In the second place, s…

Sympathetic neurons can produce and respond to interleukin 6

1998

Neuronal expression of cytokines is an area of active investigation in the contexts of development, disease, and normal neural function. Although cultured rat sympathetic neurons respond very weakly to exogenous interleukin 6 (IL-6), we find that addition of soluble IL-6 receptor (sIL-6R) and IL-6 enhances neuronal survival in the absence of nerve growth factor. Neutralizing monoclonal antibodies against IL-6 block these effects. Addition of IL-6 and sIL-6R also induces a subset of neuropeptide and transmitter synthetic enzyme mRNAs identical to that demonstrated for leukemia inhibitory factor, ciliary neurotrophic factor, and oncostatin M. Both of these effects are duplicated by addition o…

Cell and Tissue Response to Modified by Laser-induced Periodic Surface Structures Biocompatible Materials for Dental Implants

2016

The use of femtosecond laser-induced periodic surface structures (LIPSS) for dental implants surface modification for improving cell adhesion and proliferation is reported. Results demonstrated higher response of cells on modified surface compared to untreated ones.

A molecular dynamics study of large-scale reversible aggregation of anisotropic particles

1992

We report findings of 1000 ps molecular dynamics simulations of a bidimensional system of 4050 Lennard–Jones particles with electric dipoles, undergoing spinodal separation. This simple system is used to model the reversible aggregation of building blocks bearing specific and fixed adhesion sites at their surface. Aggregation regions so obtained resemble images of self-assembled biological structures. Statistical analyses of these regions evidence the interplay of thermodynamic instability and of interaction range between the attachment sites. They also illustrate some basic aspects of the morphogenesis of extended biomolecular/cellular structures, self-organized from initially homogeneous …

Mixed Polymer Brushes: Switching of Surface Behavior and Chemical Patterning at the Nanoscale

2005

Interface Diffusion Controlled Sintering of Atomically Clean Surfaces of Metals

2003

New solutions of preparation and activation of surfaces

2017

Organic coatings applied on the surface of cast iron pipes ensure very good chemical and anti-corrosion protection against aggressive effluents. To improve adherence between coating (epoxy) and substrate, a surface preparation is required. Among conventional processes shot blasting has emerged as the most efficient and cheapest solution for ensuring stripping while generating adapted roughness. However, as it may enhance both mechanical anchorage and chemical bonding a better understanding of these phenomena should be developed. Besides new eco-friendly alternatives were investigated.Indeed, new techniques were evaluated, i.e. laser structuring and an ultra-high pressure water jet whose maj…

Human intestinal Vdelta1+ lymphocytes recognize tumor cells of epithelial origin.

1996

gammadelta T cells can be grouped into discrete subsets based upon their expression of T cell receptor (TCR) variable (V) region families, their tissue distribution, and their specificity. Vdelta2+ T cells constitute the majority of gammadelta T cells in peripheral blood whereas Vdelta1+T cells reside preferentially in skin epithelium and in the intestine. gammadelta T cells are envisioned as first line host defense mechanisms capable of providing a source of immune effector T cells and immunomodulating cytokines such as interleukin (IL) 4 or interferon (IFN) gamma. We describe here the fine specificity of three distinct gammadelta+ tumor-infiltrating lymphocytes (TIL) obtained from patient…