Search results for "Adolescent"

showing 10 items of 6718 documents

The Prevalence and Consequences of Adverse Childhood Experiences in the German Population

2019

Background Multiple studies have shown a link between cumulative adverse experiences in childhood and a wide variety of psychosocial problems in later life. There have not been any pertinent representative studies of the German population until now. The goal of this study is to determine the frequency of adverse childhood experiences (ACE), the extent to which they manifest themselves in patterns of co-occurrence, and their possible connection to psychosocial abnormalities in the German population. Methods 2531 persons (55.4% female) aged 14 years and up (mean [M] = 48.6 years, standard deviation [SD] = 18) were retro- spectively studied for ACE and psychosocial abnormalities by means of th…

AdultMaleAdolescentPoison controlYoung Adult03 medical and health sciences0302 clinical medicineAdverse Childhood ExperiencesGermanyCorrespondenceInjury preventionPrevalenceHumansMedicinePsychological abuseAgedRetrospective Studiesbusiness.industryMental DisordersLife satisfactionGeneral MedicineOdds ratioMiddle Agedmedicine.diseaseLatent class model030227 psychiatrySubstance abuseAdult Survivors of Child Adverse EventsFemaleOriginal ArticlebusinessPsychosocial030217 neurology & neurosurgeryClinical psychology
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Gender-specific associations of loneliness and suicidal ideation in a representative population sample: Young, lonely men are particularly at risk

2021

Loneliness has been related to negative physical and mental health outcomes including suicidal ideation (SI). However, it is not clear whether loneliness is equally important for SI in women and men and in individuals of all age groups.Participants were a representative population sample (N=2,450) comprising the entire adult age range (18-95 years). Participants filled out established questionnaires (UCLA Three-Item Loneliness Scale, Beck Scale for Suicide Ideation, Patient Health Questionnaire-4). We tested a multiple linear regression model of SI (controlling for income, living alone, and mental distress) with interaction terms (loneliness x gender, loneliness x age, gender x age, lonelin…

AdultMaleAdolescentPopulation samplePopulationAdult ageSuicidal IdeationYoung AdultMental distressRisk FactorsmedicineSuicide ideationHumanseducationSuicidal ideationAgedAged 80 and overeducation.field_of_studyLonelinessMental DisordersLonelinessMiddle AgedMental healthPsychiatry and Mental healthClinical PsychologyCross-Sectional StudiesFemalemedicine.symptomPsychologyClinical psychologyJournal of Affective Disorders
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Age and gender differences in anxiety and depression in cancer patients compared with the general population.

2019

Objective The aim of this study was to compare the levels of anxiety and depression in cancer patients with those of the general population, to examine age and gender differences in anxiety and depression, to analyse the impact of several socio-demographic and clinical parameters on anxiety and depression, and to test the age and gender measurement invariance of the Hospital Anxiety and Depression Scale (HADS). Methods A sample of 3,785 German patients with cancer and a sample of 2,747 people of the German general population were examined using the HADS. Results Patients with cancer were more anxious but slightly less depressed than age- and gender-matched individuals of the general populat…

AdultMaleAdolescentPopulationAnxietyHospital Anxiety and Depression ScaleAge and gender03 medical and health sciencesYoung Adult0302 clinical medicineSex FactorsGermanyNeoplasmsmedicineHumansMeasurement invarianceeducationDepression (differential diagnoses)AgedNeoplasm Stagingeducation.field_of_studyDepressive DisorderPerformance statusbusiness.industryDepressionAge FactorsCancerMiddle Agedmedicine.diseaseAnxiety DisordersOncology030220 oncology & carcinogenesisCase-Control StudiesAnxietyFemalemedicine.symptombusinessClinical psychologyEuropean journal of cancer careREFERENCES
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HLA-Cw4 Association with Acute Lymphoblastic Leukaemia in Sicilian Patients

1988

The HLA frequencies of 50 Sicilian patients affected with acute lymphoblastic leukaemia (ALL) were examined. The frequency of Cw4 antigen was significantly increased in patients. Thus results obtained in our homogeneous population confirm in part previous reports suggesting that Cw4-related genetic factors might be involved in the susceptibility to aetiological or pathogenetic mechanisms which play a role in some haematological malignancies.

AdultMaleAdolescentPopulationHLA-C AntigensHuman leukocyte antigenPathogenesisAntigenHLA AntigensAcute lymphocytic leukemiamedicineHumanseducationSicilyeducation.field_of_studybusiness.industryHematologyGeneral Medicinemedicine.diseaseLeukemia LymphoidLeukemiaChild PreschoolImmunologyEtiologyLymphoblastic leukaemiaFemalebusinessVox Sanguinis
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Adolescent physical fitness and activity as predictors of adulthood activity.

2011

A 25-year population-based study was conducted to determine how physical fitness and participation in leisure-time physical activity in adolescence (age 12-18 years) predict leisure-time physical activity in adulthood (age 37-43 years). In 1976, five field tests were conducted to measure muscular fitness, agility and aerobic capacity, and self-report weekly frequencies of activity were obtained by questionnaire. A modified questionnaire was repeated in 2001, when participants were age 37-43 years (N = 1525). On the basis of the questionnaire, a physical activity index was calculated both in 1976 and 2001. The odds ratios (OR) for being inactive in adulthood among those who were physically v…

AdultMaleAdolescentPopulationPhysical fitnessPhysical activityPhysical Therapy Sports Therapy and RehabilitationField testsDevelopmental psychologyLeisure ActivitiesSex FactorsSex factorsRisk FactorsSurveys and QuestionnairesOdds RatioHumansOrthopedics and Sports MedicineLongitudinal StudieseducationSelf reportChildExerciseSedentary lifestyleeducation.field_of_studybusiness.industryOdds ratioPhysical FitnessFemaleSelf ReportSedentary BehaviorPsychologybusinessDemographyJournal of sports sciences
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Post-extraction mesio-distal gap reduction assessment by confocal laser scanning microscopy - a clinical 3-month follow-up study

2017

[EN] AimThe aim of this 3-month follow-up study is to quantify the reduction in the mesio-distal gap dimension (MDGD) that occurs after tooth extraction through image analysis of three-dimensional images obtained with the confocal laser scanning microscopy (CLSM) technique. Materials and MethodsFollowing tooth extraction, impressions of 79 patients 1month and 72 patients 3months after tooth extraction were obtained. Cast models were processed by CLSM, and MDGD changes between time points were measured. ResultsThe mean mesio-distal gap reduction 1month after tooth extraction was 343.4m and 3months after tooth extraction was 672.3m. The daily mean gap reduction rate during the first term (bet…

AdultMaleAdolescentPost-extraction changesESTADISTICA E INVESTIGACION OPERATIVAINGENIERIA QUIMICAYoung Adult03 medical and health sciencesImaging Three-Dimensional0302 clinical medicinestomatognathic systemImage Interpretation Computer-AssistedSocket healingConfocal laser scanning microscopyHumansMedicineMesio-distal distanceConfocal laser scanning microscopyProspective Studies030212 general & internal medicineTooth SocketAgedMicroscopy Confocalbusiness.industry030206 dentistryMiddle AgedTooth ExtractionPeriodonticsFemaleNuclear medicinebusinessGap reductionFollow-Up StudiesMonth follow up
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Influence of dental occlusion on postural control and plantar pressure distribution.

2016

The number of studies investigating correlations between the temporomandibular system and body posture, postural control or plantar pressure distribution is continuously increasing. If a connection can be found, it is often of minor influence or for only a single parameter. However, small subject groups are critical. This study was conducted to define correlations between dental parameters, postural control and plantar pressure distribution in healthy males.In this study, 87 male subjects with an average age of 25.23 ± 3.5 years (ranging from 18 to 35 years) were examined. Dental casts of the subjects were analyzed. Postural control and plantar pressure distribution were recorded by a force…

AdultMaleAdolescentPostureDentistryPostural controlDental Occlusion03 medical and health sciences0302 clinical medicinestomatognathic systemSurveys and QuestionnairesPressureMedicineDistribution (pharmacology)HumansForce platformGeneral DentistryPostural BalanceOrthodonticsDental occlusionBody posturebusiness.industryFootPlantar pressure030206 dentistrystomatognathic diseasesOtorhinolaryngologybusiness030217 neurology & neurosurgeryCranio : the journal of craniomandibular practice
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[Use of flunitrazepam for sedation in digestive endoscopy. Our experience].

1988

Use of flunitrazepam for sedation in digestive endoscopy. Our experience

AdultMaleAdolescentPremedicationEndoscopyFlunitrazepamAnxietyMiddle AgedSettore MED/18 - Chirurgia GeneraleanxioliticsSurveys and QuestionnairesGastroscopyHumansFemaleSettore MED/25 - PsichiatriaAgedMinerva chirurgica
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Secondary tactile hypoesthesia: a novel type of pain-induced somatosensory plasticity in human subjects

2004

Quantitative sensory testing revealed that pain induced by intracutaneous capsaicin injection elicited secondary hyperalgesia coexisting with secondary tactile hypoesthesia. Mapping the areas of altered mechanical sensations adjacent to the capsaicin injection disclosed that the area of secondary hyperalgesia was always nested in a larger area of secondary hypoesthesia easily detected as numbness by most subjects. Psychometric functions revealed a twofold rightward shift of tactile detection (hypoesthesia), which coexisted with a more than fourfold leftward shift of pricking pain detection (hyperalgesia) in the same skin area. As a mechanism we propose a functional switch at the spinal leve…

AdultMaleAdolescentPresynaptic TerminalsPainNeurological disorderSomatosensory systemSynaptic TransmissionHypesthesiachemistry.chemical_compoundmedicineHumansNeurons AfferentSkinAfferent PathwaysNerve Fibers UnmyelinatedNeuronal PlasticityGeneral NeuroscienceNociceptorsPeripheral Nervous System DiseasesNeural InhibitionHypoesthesiaMiddle Agedmedicine.diseaseMechanoreceptorNociceptionmedicine.anatomical_structurechemistryTouchCapsaicinAnesthesiaHyperalgesiaNociceptorFemaleCapsaicinmedicine.symptomPsychologyMechanoreceptorsNeuroscienceNeuroscience Letters
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Hydroxylation of collagen type I: evidence that both lysyl and prolyl residues are overhydroxylated in osteogenesis imperfecta

1995

The composition of the collagens secreted into the media of fibroblast cultures of 39 patients with osteogenesis imperfecta (OI) was the same in controls and OI cultures. An abnormal migration pattern of collagens upon SDS-PAGE was evident in one third of the cultures investigated. Lysyl and prolyl hydroxylation of HPLC-purified alpha 1(I) chains was elevated in about 60% of cultures. The degree of hydroxylation was highest in the lethal forms. The extent of lysyl and prolyl hydroxylation showed a strong correlation (r = 0.74, P < 0.001). While high levels of hydroxylation are frequently observed in OI patients, a direct correlation between lysyl or prolyl hydroxylation and fracture rate or…

AdultMaleAdolescentProlineClinical BiochemistryAlpha (ethology)Fibroblast culturesHydroxylationHydroxylysineBiochemistryHydroxylationFractures Bonechemistry.chemical_compoundHydroxyprolinePregnancymedicineHumansChildCells CulturedCollagen typeGrowth retardationLysineInfantGeneral MedicineFibroblastsMiddle AgedOsteogenesis Imperfectamedicine.diseaseMolecular biologyBody HeightHydroxyprolineHydroxylysinePhenotypechemistryBiochemistryOsteogenesis imperfectaChild PreschoolFemaleCollagenEuropean Journal of Clinical Investigation
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