Search results for "Adults"

showing 10 items of 521 documents

Study on the Acceptability of an ICT Platform for Older Adults with Mild Cognitive Impairment

2020

EhcoBUTLER is an Information and Communication Technology (ICT) solution funded by the European Union (H2020; ID: 643566) and intended especially for elderly people with mild cognitive impairment (MCI) to improve their health, independence and quality of life, particularly at the social level. The purpose of this study is to assess the acceptability of ehcoBUTLER based on a survey delivered to potential users and actors involved in their care, exploring their expectations and preferences, while anticipating the system’s functional requirements. The survey was delivered online to 313 participants (11% end users, 25% informal caregivers, 48% formal caregivers and 16% administration/management…

MaleApplied psychologyMedicine (miscellaneous)AnxietyHealth informaticscognitive trainingUser-Computer Interface0302 clinical medicineHealth Information Management030212 general & internal medicinepsychosocial stimulationolder adultsmedia_commonAged 80 and overAttitude to ComputersDepressionTecnologia de la informacióHuman factors and ergonomicsPatient PreferenceMiddle AgedPreferenceCognitive trainingEuropeCaregiversFemalePsychologyInformation TechnologyInformation SystemsHealth InformaticsHealth Promotion03 medical and health sciencesQuality of life (healthcare)acceptabilitymedia_common.cataloged_instanceHumansAdultsCognitive DysfunctionInterpersonal RelationsHealthy LifestyleEuropean unionComunicació i tecnologiaAgedEnd userbusiness.industryMCIInformation and Communications TechnologyICTQuality of LifeErgonomicsbusiness030217 neurology & neurosurgery
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Neuroblastoma after Childhood: Prognostic Relevance of Segmental Chromosome Aberrations, ATRX Protein Status, and Immune Cell Infiltration

2014

AbstractNeuroblastoma (NB) is a common malignancy in children but rarely occurs during adolescence or adulthood. This subgroup is characterized by an indolent disease course, almost uniformly fatal, yet little is known about the biologic characteristics. The aim of this study was to identify differential features regarding DNA copy number alterations, α-thalassemia/mental retardation syndrome X-linked (ATRX) protein expression, and the presence of tumor-associated inflammatory cells. Thirty-one NB patients older than 10 years who were included in the Spanish NB Registry were considered for the current study; seven young and middle-aged adult patients (range 18-60 years) formed part of the c…

MaleCancer ResearchHet heterogeneousGene ExpressionNeuroblastomaImmunophenotypingRegistriesYoung adultNeoplasm MetastasisMLPA multiplex ligation probe amplificationChildIn Situ Hybridization FluorescenceNuclear ProteinsMiddle AgedAYA adolescent and young adultsPrognosislcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogensNCA numerical chromosome aberrationImmunohistochemistryFemaleSCA segmental chromosome aberrationIHC immunohistochemistryNB neuroblastomaAdultX-linked Nuclear ProteinAdolescentaSNP single nucleotide polymorphism arrayBiologyMalignancyChromosome aberrationPolymorphism Single Nucleotidelcsh:RC254-282ArticleImmunophenotypingYoung AdultLymphocytes Tumor-InfiltratingNeuroblastomacnLOH copy-neutral loss of heterozygositymedicineHumansHom homogeneousATRXNeoplasm StagingChromosome AberrationsDNA Helicasesmedicine.diseaseSpainMNNA MYCN not amplifiedCancer researchFSCA focal segmental chromosome aberrationCD8MNA MYCN amplifiedNeoplasia
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Survival of European children and young adults with cancer diagnosed 1995-2002

2009

This study analyses survival in 40,392 children (age 0-14 years) and 30,187 adolescents/young adults (age 15-24 years) diagnosed with cancer between 1995 and 2002. The cases were from 83 European population-based cancer registries in 23 countries participating in EUROCARE-4. Five-year survival in countries and in regional groupings of countries was compared for all cancers combined and for major cancers. Survival for 15 rare cancers in children was also analysed. Five-year survival for all cancers combined was 81% in children and 87% in adolescents/young adults. Between-country survival differences narrowed for both children and adolescents/young adults. Relative risk of death reduced signi…

MaleCancer ResearchPediatricsMESH : Child PreschoolAdolescentsMESH: Epidemiologic Methods[ SDV.CAN ] Life Sciences [q-bio]/Cancer0302 clinical medicineMESH : ChildNeoplasmsMESH: ChildEpidemiologyMESH: NeoplasmsMESH : Female030212 general & internal medicineYoung adultChildChildrenChildren & young adults; Cancer survivalMESH : InfantPopulation-based cancer registriesChildren & young adultsMESH: Infant3. Good healthEuropeEastern europeanOncologyMESH: Young AdultChild Preschool030220 oncology & carcinogenesisMESH : Rare DiseasesRare tumoursFemaleMESH: Rare Diseasesmedicine.medical_specialtyAdolescentMESH : MaleMESH : EuropeMESH : Young AdultSocio-culturale[SDV.CAN]Life Sciences [q-bio]/CancerMESH : Epidemiologic MethodsYoung Adult03 medical and health sciencesRare DiseasesSDG 3 - Good Health and Well-beingMESH : AdolescentmedicineHumansPreschoolAdolescents; Cancer survival; Children; Europe; Population-based cancer registries; Rare tumours; Young adults; Adolescent; Child; Child Preschool; Epidemiologic Methods; Europe; Female; Humans; Infant; Male; Neoplasms; Rare Diseases; Young Adult; Oncology; Cancer ResearchSurvival analysisMESH: AdolescentMESH: Humansbusiness.industryMESH: Child PreschoolMESH : HumansInfantCancermedicine.diseaseMESH : NeoplasmsCancer survivalMESH: MaleCancer registryEl NiñoRelative riskMESH: EuropeEpidemiologic MethodsbusinessMESH: FemaleYoung adults
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Physical multimorbidity and depression: A mediation analysis of influential factors among 34,129 adults aged ≥50 years from low- and middle-income co…

2022

Background There is a scarcity of literature on the association between physical multimorbidity (i.e., >= 2 chronic physical conditions) and depression among older adults, especially from low- and middle-income countries (LMICs). In addition, the mediators in this association are largely unknown. Therefore, we aimed to examine this association among adults aged >= 50 years from six LMICs (China, Ghana, India, Mexico, Russia, and South Africa), and to identify potential mediators. Methods Cross-sectional, nationally representative data from the Study on Global Ageing and Adult Health were analyzed. Depression was defined as past-12 months DSM-IV depression or receiving depression treat…

MaleChinaMediation AnalysisDepressiondepression low- and middle-income countries mediation middle-age adults multimorbidity older adultsMultimorbidityA mediation analysis of influential factors among 34129 adults aged ≥50 years from low- and middle-income countries.- Depression and anxiety 2022 [Smith L. Shin J. I. Butler L. Barnett Y. Oh H. Jacob L. Kostev K. Veronese N. Soysal P. Tully M. et al. -Physical multimorbidity and depression]Psychiatry and Mental healthClinical PsychologyCross-Sectional StudiesChronic DiseasePrevalenceHumansFemaleDeveloping CountriesAgedDepression and anxietyREFERENCES
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Association between food insecurity and depression among older adults from low- and middle-income countries.

2021

Background:\ud \ud To examine the association between self‐reported food insecurity and depression in 34,129 individuals aged ≥50 years from six low‐ and middle‐income countries (LMICs) (China, Ghana, India, Mexico, Russia, and South Africa).\ud \ud Methods:\ud \ud Cross‐sectional, community‐based, nationally representative data from the WHO Study on global AGEing and adult health (SAGE) were analyzed. Self‐reported past 12‐month food insecurity was assessed with two questions on frequency of eating less and hunger due to lack of food. Questions based on the World Mental Health Survey version of the Composite International Diagnostic Interview were used for the endorsement of past 12‐month …

MaleChinaPsychological interventionIndiaLogistic regressionGhanaOddsRussia03 medical and health sciencesSouth Africa0302 clinical medicineolder adults.Environmental healthfood insecurityPrevalenceMedicineHumanslow- and middle-income countriesAssociation (psychology)Developing CountriesMexicoDepression (differential diagnoses)older adultsAged2. Zero hungerbusiness.industry1. No povertyMiddle Aged*low- and middle-income countriesMental healthConfidence interval3. Good health030227 psychiatryFood insecurityPsychiatry and Mental healthClinical PsychologyCross-Sectional Studieslow- and middle-income countriedepressionFemale[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie*food insecuritybusiness*older adultsSmith L. Il Shin J. McDermott D. Jacob L. Barnett Y. López-Sánchez G. F. Veronese N. Yang L. Soysal P. Oh H. et al. -Association between food insecurity and depression among older adults from low- and middle-income countries.- Depression and anxiety 2021030217 neurology & neurosurgery*depression
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Epidemiology of Chronic Pain in the Latium Region, Italy. a Cross-sectional Study on the Clinical Characteristics of Patients Attending Pain Clinics

2019

In Italy, chronic pain affects more than a quarter of the population, whereas the average European prevalence is 21%. This high prevalence might be due to the high percentage of Italian people who do not receive treatment, even after the passing of law 38/2010 (the right to access pain management in Italy), which created a regional network for the diagnosis and treatment of noncancer chronic pain. Italian epidemiologic studies on chronic pain are scanty, and this observational, multicenter, cross-sectional study is the first to investigate the clinical characteristics of patients who attended the pain management clinics in the Latium Region, Italy, for the management of their noncancer chro…

MaleCross-sectional studyIMPACTEpidemiology chronic pain pain clinicschronic non-malignant pain0302 clinical medicinenursingRisk FactorsEpidemiologyPrevalence030212 general & internal medicineeducation.field_of_studyHigh prevalence030504 nursingChronic painMiddle AgedSettore MED/45 - Scienze Infermieristiche Generali Cliniche E PediatricheAREItalygender differencesFemaleepidemiologyHEALTH0305 other medical scienceBURDENPRESENTEEISMchronic painpain management; chronic pain; gender differences; chronic non-malignant pain; epidemiologyAdultmedicine.medical_specialtyPopulation03 medical and health sciencesPREVALENCE IMPACT BURDENARE DISABILITY MANAGEMENT HEALTH PRESENTEEISM SEVERITY ADULTSInternal medicinemedicineMANAGEMENTHumanseducationAgedAdvanced and Specialized Nursingbusiness.industryDISABILITYADULTSPain managementmedicine.diseasePain ClinicsSEVERITYCross-Sectional Studiespain managementPain ClinicsObservational studybusiness
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Prevalence of diphtheria toxin antibodies in human sera from a cross-section of the Italian population.

1999

Abstract A polycentric study was carried out between 1993 and 1995 in order to evaluate diphtheria immunity on a representative sample of population from different areas of Italy. To determine diphtheria antitoxin, sera from 5187 apparently healthy subjects, divided according to sex and age groups, were titrated using an ELISA indirect method. A basic protective titre of diphtheria antitoxin (>0.01 IU ml −1 ) was found in 4080 (78.6%) subjects. No statistically significant differences between males and females were observed. Our findings show that the proportion of susceptibles increases with age and a high proportion of adults no longer has diphtheria antitoxin at protective levels since t…

MaleCross-sectional studySerologySeroepidemiologic StudiesPrevalenceCluster AnalysisDiphtheria ToxinChildAged 80 and overeducation.field_of_studybiologyImmunoenzyme techniquesDiphtheriaMiddle AgedAntibodies BacterialInfectious DiseasesItalyChild PreschoolCross-sectional studiesMolecular MedicineFemaleAdults; Cross-sectional studies; Diphtheria; Diphtheria antitoxin; Immunoenzyme techniques; ItalyAntibodyAdultDiphtheria antitoxinAdolescentPopulationcomplex mixturesNOAge DistributionImmunitymedicineHumansAdultsSex DistributioneducationAgedDiphtheria toxinGeneral VeterinaryGeneral Immunology and Microbiologybusiness.industryDiphtheriaPublic Health Environmental and Occupational HealthInfantmedicine.diseaseDiphtheria; Diphtheria antitoxin; Cross-sectional studies; Immunoenzyme techniques; Adults; ItalyImmunologyHumoral immunitybiology.proteinbusiness
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The use of national administrative data to describe the spatial distribution of in-hospital mortality following stroke in France, 2008-2011.

2016

International audience; Background: In the context of implementing the National Stroke Plan in France, a spatial approach was used to measure inequalities in this disease. Using the national PMSI-MCO databases, we analyzed the in-hospital prevalence of stroke and established a map of in-hospital mortality rates with regard to the socio-demographic structure of the country.Methods: The principal characteristics of patients identified according to ICD10 codes relative to stroke (in accordance with earlier validation work) were studied. A map of standardized mortality rates at the level of PMSI geographic codes was established. An exploratory analysis (principal component analysis followed by …

MaleDatabases FactualBusiness Management and Accounting(all)Health informatics0302 clinical medicineEpidemiology030212 general & internal medicineHospital MortalityStrokeAged 80 and overGeographyMortality rategbd 2013Middle Aged3. Good healthStrokeIn-hospital mortalityFemaleFranceComputer Science(all)trendsAdultmedicine.medical_specialtyGeneral Computer ScienceHealth geographyunited-statesprevalenceMEDLINEContext (language use)03 medical and health sciences[ SDV.MHEP ] Life Sciences [q-bio]/Human health and pathologymedicineHumanscareAgedDemographydiseasebusiness.industrycigarette-smokingPublic healthResearchglobal burdenPublic Health Environmental and Occupational HealthPMSImedicine.diseaseyoung-adultsGeneral Business Management and Accountingtransient ischemic attackbusiness030217 neurology & neurosurgery[SDV.MHEP]Life Sciences [q-bio]/Human health and pathologyDemographyInternational journal of health geographics
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The association of cooking fuels with depression and anxiety symptoms among adults aged ≥65 years from low- and middle-income countries

2022

Background: We aimed to investigate associations of unclean cooking fuels with depression and anxiety symptoms in a large sample of adults aged ≥65 years from six low- and middle-income countries (LMICs). Methods: Cross-sectional, community-based, nationally representative data from the WHO Study on global AGEing and adult health (SAGE) were analyzed. Unclean cooking fuel referred to kerosene/paraffin, coal/charcoal, wood, agriculture/crop, animal dung, and shrubs/grass. Depression referred to DSM-IV depression based on past 12-month symptoms or receiving depression treatment in the last 12 months. Anxiety symptoms referred to severe/extreme problems with worry or anxiety in the past 30 day…

MaleDepressionDepression; Low- and middle-income countriesAnxietyCooking fuelAnxiety Cooking fuel Depression Low- and middle-income countries Mental health Older adults Sustainable goal 7Psychiatry and Mental healthClinical PsychologySustainable goal 7Cross-Sectional StudiesAir Pollution IndoorOlder adultsHumansFemaleMental healthCookingDeveloping Countries
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Analysis of the impact of a cognitive task on the posture of elderly subjects with depression compared with healthy elderly subjects

2016

International audience; Objective: While previous studies have demonstrated that depressive elderly subjects (DES) experience difficulties in the processing of simultaneous cognitive tasks, few have examined the coupling of cognitive tasks with seemingly 'automatic' tasks, such as standing upright. Current patient management focuses on pharmacological treatments and cognitive-behavioral therapies.Methods: Healthy elderly (HES) and non-treated DES were included. Postural sway in DES was compared with that in HES while in single-task and dual-task conditions. The single-task consisted of standing upright. For the dual-task, the subjects recalled various items from memory or counted while stan…

MaleElementary cognitive taskmedicine.medical_specialtyfall riskPosturePoison controlStatic posturegaitbehavioral disciplines and activities03 medical and health sciencesCognition0302 clinical medicinePhysical medicine and rehabilitationElderlyCenter of pressure (terrestrial locomotion)older-peoplePhysiology (medical)Injury preventionmedicineadultsHumans030212 general & internal medicinePostural BalanceAgedAged 80 and overDepressionHuman factors and ergonomicsPostural controlCognitionHealthy elderlyHealthy VolunteersSensory SystemsmotorretardationPatient managementCognitive taskDual-taskNeurology[ SDV.NEU ] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]basal gangliaFemaleNeurology (clinical)abnormalitiesPsychologymajor depressionPsychomotor Performance030217 neurology & neurosurgerypsychological phenomena and processesmetaanalysis
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