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Electrochemical treatment of aqueous solutions of catechol by various electrochemical advanced oxidation processes: Effect of the process and of oper…

2017

Abstract Catechol, one of the most abundant compounds in olive mills wastewaters, which is generated in the Fenton degradation of various aromatic compounds, is a toxic, possible carcinogen, persistent pollutant and it is not readily biodegradable. Hence, its degradation requires the utilization of advanced oxidation processes (AOPs). Here, the electrochemical treatment of aqueous solutions of catechol was investigated. The utilization of various electrochemical processes, such as electro-Fenton (EF), direct anodic oxidation (AO), indirect oxidation by electro-generated active chlorine and coupled processes was investigated. Furthermore, the effect of various operating conditions (including…

Alterations of regional cerebral blood flow and oxygen saturation in a rat sinus-vein thrombosis model.

1996

Background and Purpose The pathophysiology of sinus-vein thrombosis (SVT) in patients and experimental animals is still poorly understood. This study was designed to examine and further elucidate the pathophysiological sequence of events, especially the relationship between local and regional blood flow and hemoglobin oxygen saturation (HbSO 2 ) detected at identical locations. The use of both parameters as outcome indicators should be compared. Methods SVT was induced by ligation of the superior sagittal sinus (SSS) and slow injection of kaolin-cephalin suspension into the SSS in rats. Regional cerebral blood flow (rCBF) was assessed by laser-Doppler flowmetry together with regional HbSO …

205 Minimally invasive approaches in locally advanced cervical cancer patients undergoing radical surgery after chemoradiotherapy: a propensity score…

2020

Objectives To evaluate the oncological and surgical outcome of minimally invasive radical surgery (MI-RS) compared to open radical surgery (O-RS) in locally advanced cervical cancer (LACC) after preoperative chemoradiation (CT/RT). Methods Data relative to stage IB2-IVA cervical cancer patients managed by CT/RT and RS were retrospectively analyzed. Results Starting from 686 patients, the propensity score matching resulted in 462 cases (231 per group), balanced for FIGO stage, lymph node status, histotype, tumor grade and clinical response to CT/RT. Overall, 107 recurrences were registered with no difference in the pattern of recurrences between the two surgical approaches. The 5-year diseas…

Neoadjuvant chemotherapy, TUR and radiotherapy in T2-T4 NO MO bladder carcinoma

1997

– Forty patients affected by locally advanced carcinoma of the bladder were submitted to up-front chemotherapy followed by TUR and radiotherapy. A complete response was obtained in 27 patients (67.5%). A residual mass was present in 13 (32.5%) patients. At a mean follow-up of 38 months (range: 18–112 months), 7 patients showed a recurrence that was superficial in 3 cases and infiltrating the muscular layer in 4. Fifteen patients (37.5%), 12 of whom disease-free, are alive with a mean survival of 65 months. Five more patients died of non-related disease.

High-performance liquid chromatographic determination of furfural compounds in infant formulas during full shelf-life

2005

Abstract In order to evaluate the extent of the Maillard reaction in adapted and follow-up infant formulas (IF), a study was made of the evolution of furfural compound (2-furaldehyde, 5-hydroxymethyl-2-furfuraldehyde, 2-furylmethylketone and 5-methyl-2-furaldehyde) in these products, along with their relation to available lysine during the shelf-life period (two years at 20 and 37 °C). Total and free furfural contents were measured by RP-HPLC and UV detection, heating or not the sample in boiling water to free the furfurals bound to proteins and the furfurals formed from precursors. Only 2-furylmethylketone and 5-hydroxymethyl-2-furfuraldehyde were detected. Adapted and follow-up IF showed …

Protein/lipid coaggregates are formed during α-synuclein-induced disruption of lipid bilayers.

2014

Amyloid formation is associated with neurodegenerative diseases such as Parkinson's disease (PD). Significant α-synuclein (αSN) deposition in lipid-rich Lewy bodies is a hallmark of PD. Nonetheless, an unraveling of the connection between neurodegeneration and amyloid fibrils, including the molecular mechanisms behind potential amyloid-mediated toxic effects, is still missing. Interaction between amyloid aggregates and the lipid cell membrane is expected to play a key role in the disease progress. Here, we present experimental data based on hybrid analysis of two-photon-microscopy, solution small-angle X-ray scattering and circular dichroism data. Data show in real time changes in liposome …

Role of positron emission tomography (PET) in advanced stage non-small cell lung cancer patients treated with cisplatin-based doublets

2008

LEOPARD-II: A randomized phase II study of radiochemotherapy (RCT) with 5FU and cisplatin plus/minus cetuximab (Cet) in unresectable locally advanced…

2014

4081 Background: Patients (pts) with LAEC have a poor prognosis; new therapies are required. A study showed the addition of Cet to RCT to be safe and effective for resectable EC [Ruhstaller et al, ...

Mapping Actual Evapotranspiration by Combining Landsat TM and NOAA-AVHRR Images: Application to the Barrax Area, Albacete, Spain

1998

Abstract A method that permits determination of actual evapotranspiration, ET, in heterogeneous areas has been proposed. It is based on the relation ET = ET m − B ( T s − T sm ), which combines meteorological, National Oceanic and Atmospheric Administration advanced very high resolution radiometer (NOAA-AVHRR), and Landsat thematic mapper (TM) data. Thus, the maximum evapotranspiration for each crop, ETm, is obtained from in situ measurements carried out in a meteorological station; the temperature difference between each pixel and the pixel that has the maximum evapotranspiration, Ts−Tsm, is calculated for each crop from NOAA-AVHRR data; and the crop distribution in the area is known throu…

The use of complementary alternative medicines in advanced cancer patients followed at home

2021

Objectives: To assess the use of complementary alternative medicines (CAM) in advanced cancer patients followed at home. Methods: A consecutive sample of advanced cancer patients admitted to a home palliative care program was invited to participate in the study in a period of two months. Demographic characteristics, religious belief, education level, diagnosis, and socio-economic condition were recorded. Patients were asked about the use of CAM, considered to be a health-related treatment practiced outside the established health services. Information about CAM indications and those who prescribed or suggested CAM were also collected. Results: Two hundred and eighty-three advanced cancer pat…