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showing 10 items of 750 documents

Primary Analysis of Phase 2 Results for Cemiplimab in Patients (pts) with Locally Advanced Basal Cell Carcinoma (laBCC) who Progress on or are Intole…

2021

Abstract not available.

business.industryLocally advancedmedicineCancer researchBasal cell carcinomaIn patientmedicine.diseasebusinessHedgehogSKIN The Journal of Cutaneous Medicine
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Sport and Quality of Life

2022

Negli ultimi trent’anni lo sport ha assunto un significato molto rilevante nella vita delle persone e, seppure con notevoli differenze, sia nei paesi a sviluppo economico avanzato, sia in quelli in via di sviluppo. A livello individuale, esso ha costituito un’area di investimento identitario quando ha assunto la forma di sport spettacolo del quale fruire, alimentando la pratica del tifo e il fandom o costituendo il modello di uno stile di vita vincente; ma anche quando ha assunto la forma di pratica del tempo libero attraverso la quale tenersi in forma, facendo crescere, in questo caso, la diffusione di una cultura della salute e del benessere. Si tratta di due modalità di approcciare al co…

but also when he took the form of free time practice through which to keep fit making grow in this case the diffusion of a culture of health and well-being. These are two ways of approaching the consumption of sports by spectators and actorIn the last thirty years sport has taken on a very significant meaning in people's lives and albeit with considerable differences both in advanced economic development countries and in developing countries. On an individual level it constituted an area of identity investment when it assumed the shape of “sport spectacle” to be enjoyed fueling the practice of cheering and fandom or constituting the model of a winning lifestyleand the two ways of use can be strongly related to the perception and assessment of the quality of life. The “semantic universes” which however connote sport and “free time sports” have often appeared polarized. Commercial sport and sports professionalism are intertwined with the institutions of economics politics and culture which above all stress its “spectacularity” in order to capture first and foremost the audience. But also the sport of leisure time is intertwined with the actions of the institutions of economics politics and culture with the difference that these stress above all its “healthy value” aimed at the “healthy and rational” investment of time in an activity which improves the quality of life in the short medium and long period. This polarization between the consumption of sport entertainment - commercial sport - and the consumption of sport as a leisure activity - sport for all - has become increasingly interconnected precisely because of the increased collective identity demand via sport. In other words we have witnessed the spread of shape of sports entertainment that recall the importance of sports for psychophysical well-being for integration and social participation for the reduction of social inequalities ethnic and cultural differences and in which the importance assumed was weakened in the show from agonism from competition from the physical confrontation between two contenders or two teams. A sport in which we act with competitors as well as against competitors. And on the other hand we have gradually witnessed the spectacularization of sports in our free time to the point that the sharing of the results obtained through the declination of a competitive spirit that presents itself as directed no longer against other contenders but against its own performance limits it has become the way in which each person makes part of his or her own life spectacular the one he often considers most authentic. The aim of this work is to describe how the intertwining between the commercial/professional dimension of the sports show and the playful/recreational dimension of sports practice are fueled by a demand and an offer of social identity that characterizes these two “semantic universes”.Settore SPS/07 - Sociologia Generale
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A hardware skin-segmentation IP for vision based smart ADAS through an FPGA prototyping

2017

International audience; In this paper we presents a platform based design approach for fast HW/SW embedded smart Advanced Driver Assistant System (ADAS) design and prototyping. Then, we share our experience in designing and prototyping a HW/SW vision based smart embedded system as an ADAS that helps to increase the safety of car's drivers. We present a physical prototype of the vision ADAS based on a Zynq FPGA. The system detects the fatigue state of the driver by monitoring the eyes closure and generates a real-time alert. A new HW/SW codesign skin segmentation step to locate the eyes/face is proposed. Our presented new approach migrates the skin segmentation step from processing system (S…

car driver safetyComputer scienceautomotive electronicsFPGA Prototyping02 engineering and technology01 natural sciencesIP networkshardware skin segmentation IPhardware-software vision based smart embedded system[SPI]Engineering Sciences [physics]HardwareHigh-level synthesis0202 electrical engineering electronic engineering information engineeringSegmentationField-programmable gate arrayimage segmentationSkinfield programmable gate arraysVision basedbusiness.industry010401 analytical chemistryVehiclesobject detectionplatform based design0104 chemical sciences[SPI.TRON]Engineering Sciences [physics]/ElectronicsProgrammable logic devicedriver information systemsimage recognitionStreaming mediaembedded smart advanced driver assistant systemEmbedded systemFacefatigue state detectionPlatform-based design020201 artificial intelligence & image processingembedded systemsState (computer science)vision based smart ADASbusinesshardware-software codesignroad safetyComputer hardwareSoftwareFPGA prototype
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Thermo-, piezo-, photo- and chemo-switchable spin crossover iron(II)-metallocyanate based coordination polymers

2011

Abstract The design of coordination polymers (CPs) with switch and memory functions is an important subject of current interest in the search for new advanced materials with potential applications. Implementation of CPs with electronically labile iron(II) building blocks able to undergo cooperative spin crossover (SCO) behavior is a singular approach to this end. This review provides an up to date survey of a new generation of iron(II)-metallocyanate based spin crossover coordination polymers (SCO-CPs) developed during the last decade. These new solids feature structural diversity, supramolecular isomerism, interpenetrating frameworks, structure flexibility, reversible solid-state chemical …

chemistry.chemical_classificationChemistrySupramolecular chemistryStructural diversityNanotechnologyPolymerAdvanced materialsChemical reactionInorganic ChemistryChemisorptionSpin crossoverMaterials ChemistryOrganic chemistryPhysical and Theoretical ChemistryNanoscopic scaleCoordination Chemistry Reviews
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Ultrastrong composites from dopamine modified-polymer-infiltrated colloidal crystals

2015

Although strong and stiff synthetic composites have long been developed, the microstructure of today's most advanced composites has yet to achieve the sophisticated hierarchy of hybrid materials built up by living organisms. We have assembled hard and tough multilayered nanocomposites, which contain alternating layers of Fe3O4 nanoparticles and a 3-hydroxy-tyramine (dopamine) substituted polymer (dopamine modified polymer), strongly cemented together by chelation through infiltration of the polymer into the Fe3O4 mesocrystal. With a Young's modulus of 17 ± 3 GPa and a hardness of 1.3 ± 0.4 GPa the nanocomposite exhibits high resistance against elastic as well as plastic deformation. Key fea…

chemistry.chemical_classificationMaterials scienceNanocompositeProcess Chemistry and TechnologyPolymerAdhesionColloidal crystalMicrostructurechemistryMechanics of MaterialsAdvanced composite materialsGeneral Materials ScienceElectrical and Electronic EngineeringComposite materialHybrid materialMesocrystalMaterials Horizons
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Thermal properties of e-beam cured epoxy/thermoplastic matrices for advanced composite materials

2007

The aim of this work is to investigate the possibility to improve the thermal behaviour of epoxy based systems, cured by ionizing radiation, in order to produce matrices for advanced carbon fibres composites. Blends of two epoxy monomers, difunctional and trifunctional, have been polymerized by e-beam irradiation and the dynamic mechanical thermal properties have been investigated. The increase of the concentration of the trifunctional epoxy monomer in the blend causes a marked increase of the Tg, but strongly decreases the reactivity. Subsequently, blends of the same epoxy monomers with a high Tg thermoplastic toughening agent have been considered and their reactivity and the thermal prope…

chemistry.chemical_classificationThermoplasticMaterials sciencePolymers and PlasticsOrganic Chemistrythermal propertiesEpoxyCondensed Matter Physicscomposite materialelectron beam irradiationepoxy resinchemistry.chemical_compoundMonomerPolymerizationchemistryvisual_artAdvanced composite materialsMaterials Chemistryvisual_art.visual_art_mediumElectron beam processingReactivity (chemistry)Settore CHIM/07 - Fondamenti Chimici Delle TecnologieComposite materialGlass transition
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Advanced Composites and Applications: Book of abstracts

2023

The section ‘Advanced Composites and Applications’ was organized by the Institute for Mechanics of Materials of the University of Latvia (LU MMI) on 16.02.2023 as a part of the annual 81th scientific conference of the University of Latvia. It was organized remotely in Zoom. The official language of the section was English. The duration of the presentation was 10 minutes. The section was devoted to the discussion of the recent results within following topics: structure and properties of polymers and polymer-based composites, long-term properties, creep, and environmental ageing, composites for advanced applications, mechanical aspects of technology, and multifunctional properties.

composites for advanced applications:TECHNOLOGY::Engineering mechanics::Mechanical manufacturing engineering [Research Subject Categories]long-term propertiesenvironmental ageing:TECHNOLOGY::Materials science::Functional materials [Research Subject Categories]structure and properties of polymers and polymer-based composites:TECHNOLOGY::Engineering mechanics::Mechanical and thermal engineering [Research Subject Categories]creep
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Propuesta de unidad didáctica del concepto de integral y del cálculo de primitivas

2010

En este Trabajo Fin de Máster se va a proceder a desarrollar una propuesta de unidad didáctica sobre el concepto de integral y el cálculo de primitivas. Ambos temas, en orden contrario, fueron de los que me encargué de desarrollar en mis prácticas. Como trataré más adelante, la forma tradicional de introducir estos temas a los alumnos es comenzar con el cálculo de primitivas o antiderivadas para después, una vez que los alumnos tienen suficiente destreza en el cálculo de las mismas, continuar con el teorema fundamental del cálculo y la regla de Barrow, es decir, las integrales definidas, convirtiéndose dichos conceptos en transparentes para los alumnos y sin llegar a ser asimilados correcta…

cálculo integraldidáctica del análisis matemáticoadvanced mathematical thinkingintegral calculusUNESCO::PEDAGOGÍA::Preparación y empleo de profesores::Preparación de profesoresdidáctica de las matemáticasmathematics educationUNESCO::PEDAGOGÍA::Organización y planificación de la educación::Desarrollo de asignaturasUNESCO::MATEMÁTICAS
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Estudio de funciones con geogebra

2012

Nuestra investigación, “Estudio de funciones con GeoGebra”, se ha desarrollado en el “Máster Universitario en Profesor de Educación Secundaria” de la Universitat de València. El estudio se centra en cómo alcanzar una correcta comprensión de los conceptos referidos a funciones haciendo uso del GeoGebra. El problema que motiva esta investigación radica en que, en los cursos tradicionales de 2º de Bachillerato, cantidades significativas de estudiantes no logran comprender los conceptos básicos de funciones, en particular, la tasa de variación media, derivada, monotonía, extremos y concavidad. El proyecto tiene como objetivo hacer una propuesta de trabajo basada en la utilización de GeoGebra, d…

didáctica del análisis matemáticoadvanced mathematical thinkingUNESCO::PEDAGOGÍA::Preparación y empleo de profesores::Preparación de profesoresdidáctica de las matemáticasfunciones de una variable realmathematics educationreal functionsUNESCO::PEDAGOGÍA::Organización y planificación de la educación::Desarrollo de asignaturasgeogebraUNESCO::MATEMÁTICAS
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Recent Advances on the Halo- and Cyano-Trifluoromethylation of Alkenes and Alkynes

2021

Incorporation of fluorine into organic molecules is a well-established strategy in the design of advanced materials, agrochemicals, and pharmaceuticals. Among numerous modern synthetic approaches, functionalization of unsaturated bonds with simultaneous addition of trifluoromethyl group along with other substituents is currently one of the most attractive methods undergoing wide-ranging development. In this review article, we discuss the most significant contributions made in this area during the last decade (2012−2021). The reactions reviewed in this work include chloro-, bromo-, iodo-, fluoro- and cyano-trifluoromethylation of alkenes and alkynes.

difunctionalizationPharmaceutical Sciencechemistry.chemical_elementReviewAdvanced materialsalkynesAnalytical ChemistryOrganic moleculeschemistry.chemical_compoundQD241-441Unsaturated bondsDrug DiscoveryPhysical and Theoretical ChemistryTrifluoromethylalkenesTrifluoromethylationcyanotrifluoromethylationOrganic ChemistryCombinatorial chemistryhalotrifluoromethylationchemistryAlquensChemistry (miscellaneous)Fluorinesynthetic methodsMolecular MedicineQuímica orgànica
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