Search results for "Ageing"
showing 10 items of 609 documents
Influence of the e-beam irradiation and photo-oxidation aging on the structure and properties of LDPE-OMMT nanocomposite films
2012
Abstract In this paper two systems, polyethylene (LDPE) and polyethylene/commercial organo-modified montmorillonite (LDPE/OMMT) nanocomposite, were subjected to e-beam irradiation at different doses and both the molecular modifications and mechanical properties have been investigated through solubility, FT-IR, calorimetric and tensile tests. Moreover, in some of the irradiated systems photo-oxidation aging was performed and its effects were studied. The results show an enhancement with irradiation of the positive effect of the nano-filler loading, related to the increase of the mechanical properties, due to the increase of the nano-filler polymer interaction. Nevertheless calorimetric and F…
Fast field cycling NMR relaxometry as a tool to monitor Parmigiano Reggiano cheese ripening.
2020
Abstract It is widely recognized that the longer the ageing, the more valuable Parmigiano Reggiano (PR) cheese becomes, due to the improvement of its sensorial and nutritional properties. Up to now, the evaluation of PR properties has been performed on samples mainly aged up to 40 months. For this reason, this study was aimed at collecting information about the chemical-physical characteristics of PR cheeses after ageing at 24, 48 and 84 months. The basic analyses on water amount, protein content and volatile organic compounds (VOC) revealed that PR ageing is associated to the decomposition of the organic components into smaller units. This drives water molecules closer to the aforementione…
Delayed Fatherhood in Mice Decreases Reproductive Fitness and Longevity of Offspring1
2009
Abstract This study aims to analyze, in mice, the long-term effects of delayed fatherhood on reproductive fitness and longevity of offspring. Hybrid parental-generation (F0) males, at the age of 12, 70, 100, and 120 wk, were individually housed with a randomly selected 12-wk-old hybrid female. The reproductive fitness of first-generation (F1) females was tested from the age of 25 wk until the end of their reproductive life. In F1 males, the testing period ranged from the age of 52 wk until death. Breeding F1 females from the 120-wk group displayed interbirth intervals longer than females from the 12-, 70-, and 100-wk groups. Furthermore, F2 pups begotten by F1 studs exhibited weaning weight…
Impact of physical activity on response to stress in people aged 65 and over during COVID-19 pandemic lockdown.
2021
Background: The outbreak of the COVID-19 pandemic has negatively affected the lives of many people. In particular, restrictions of physical activity (PA) due to pandemic-related lockdown have impacted their psychological status. The aim of this work was to investigate the relationship between PA habits, before the pandemic and during the lockdown, and responses to stress due to home isolation during the lockdown, in older people. Methods: To this aim, an online survey addressed to people aged 65 years and over was conducted during the first pandemic wave in Italy (Study 1). To explore the effect of PA restrictions on responses to stress over time, the survey was replicated during the second…
Bem-estar psicológico na reforma: a importância da preparação dos trabalhadores para a transição
2017
O envelhecimento da população é uma realidade atual da nossa sociedade e, portanto, torna-se fundamental a criação de estratégias para que esta fase da vida seja vivida de forma positiva e saudável. Não obstante, é impossível evitar certas perdas que vão ocorrendo ao longo do envelhecimento, pois fazem parte do próprio processo. A reforma é uma dessas perdas, a nível social, com um grande impacto na vida dos indivíduos e nas famílias uma vez que todos nós somos profssionalmente ativos durante grande parte das nossas vidas. Torna- se, assim, importante a criação de estratégias precoces que habilitem as pessoas adultas e profssionalmente ativas para prepararem o seu próprio processo de reform…
Joint retirement behaviour and pension reform in the Netherlands
2022
We examine the effects of a major pension reform in 2015 on the joint retirement decisions of working couples in the Netherlands. The reform abolished the partner allowance, a state pension supplement for a nonworking partner below the state pension age. At the same time, actuarially generous early retirement arrangements were made less attractive. Using rich administrative data, we estimate a multivariate mixed proportional hazards model that distinguishes between several sources of joint retirement: financial incentives, other causal mecha-nisms that make retirement of one spouse more likely when the other spouse retires (e.g., due to complemen-tarities in leisure or social norms) and cor…
Factors contributing to the variability in muscle ageing
2012
a b s t r a c t Ageing is accompanied with a progressive loss of muscle mass and force generating capacity. Ultimately, the muscle wasting and weakness may dramatically impact on mobility and the quality of life, where the elderly has increasing problems with performing activities of daily life, such as rising from a chair or climbing stairs. The rate of structural and functional deterioration of muscle appears to vary considerably between people. Part of the variation in the 'rate of muscle ageing' is attributable to genetic factors, the timing of changes in circulating hormones and the presence or absence of chronic low-grade systemic inflammation. Where an individual cannot change much i…
Inactivity-induced oxidative stress: A central role in age-related sarcopenia?
2012
Ageing causes a progressive decline in skeletal muscle mass that may lead to decreased strength and functionality. The term sarcopenia is especially used to characterise this geriatric syndrome. Numerous conditions and behaviours are considered to accelerate the progression of sarcopenia such as chronic diseases, malnutrition and physical inactivity. As people in modern countries are more and more sedentary, the impact of physical inactivity on the prevalence of sarcopenia might be more and more important in the future. In this review, we discuss how reactive oxygen species (ROS) could mediate the effects of lifelong inactivity in the onset and progression of age-related sarcopenia. Althoug…
Predictors of decline in self-assessments of health among older people--a 5-year longitudinal study.
2001
Within the framework of the Evergreen project we examined how changes in several indicators of health and functioning and physical activity predicted a decline in self-assessments of health evaluated over a 5-year period in older people by two different measurements: self-rated health (SRH) and self-assessed change in health (SACH). The study group comprised all 75-year-old persons born in 1914 (N = 382) and living in Jyvaskyla, a town in central Finland. At baseline in 1989, 91.6%, and at follow-up 5 years later in 1994, 87.3% of those eligible participated in the interview and 77.2 and 71.3%, respectively, in the examinations in the study centre, focusing on different domains of health an…
Circulating miR-21, miR-146a and Fas ligand respond to postmenopausal estrogen-based hormone replacement therapy--a study with monozygotic twin pairs.
2014
Biological aging is associated with physiological deteriorations and its’ remodeling, which are partly due to changes in the hormonal profile. MicroRNAs are known to post-transcriptionally regulate various cellular processes associated with cell senescence; differentiation, replication and apoptosis. Measured from the serum, microRNAs have the potential to serve as noninvasive markers for diagnostics/prognostics and therapeutic targets. We analysed the association of estrogen-based hormone replacement therapy (HRT) with selected microRNAs and inflammation markers from the serum, leukocytes and muscle tissue biopsy samples obtained from 54-62 year-old postmenopausal monozygotic twins (n=11 p…