Search results for "Ageing"

Pluripotent stem cells to model Hutchinson-Gilford progeria syndrome (HGPS): Current trends and future perspectives for drug discovery

2015

Progeria, or Hutchinson-Gilford progeria syndrome (HGPS), is a rare, fatal genetic disease characterized by an appearance of accelerated aging in children. This syndrome is typically caused by mutations in codon 608 (p.G608G) of the LMNA, leading to the production of a mutated form of lamin A precursor called progerin. In HGPS, progerin accumulates in cells causing progressive molecular defects, including nuclear shape abnormalities, chromatin disorganization, damage to DNA and delays in cell proliferation. Here we report how, over the past five years, pluripotent stem cells have provided new insights into the study of HGPS and opened new original therapeutic perspectives to treat the disea…

Review of photoelastic image analysis applied to structural birefringent materials: glass and polymers

2015

Photoelasticity is particularly suitable for the analysis of the stress state in structural materials that are transparent and birefringent. Some techniques of digital photoelasticity (phase shifting and RGB) are applied to the analysis of stress field in two classes of structural materials. The first one consists of tempered glasses, such as those used in the automotive and architectural fields. The second one consists of thermoset polymers, typically used as matrices in fiber reinforced plastic structural composites. The birefringence of such resins is, in particular, exploited to investigate the development of swelling stresses and changes in fracture toughness as induced by water uptake…

The role of age and life course stage in digital consumption

2018

Digital technologies are an inherent part of consumer environments today. This dissertation investigates older adults’ usage of digital technologies by focusing on the role of age and life course stage in digital consumption in Finland. The dissertation applies theories of technology adoption and use, generations, and life course to examine older adults as digital consumers, the interrelationship between consumption and digital technologies and the effects of age and life course stage on digital consumption. The study utilises both quantitative and qualitative data from five (5) data sets. The results reveal that between the years 1999 and 2014, older adults reported more ecological and les…

Synthesis od epoxy/carbon fiber composites induced by e-beam. Study of the effect of hydrothermal ageing on thermal and mechanical properties

2010

Impact de la dépendance liée à l’âge sur l’alimentation des personnes âgées

2012

Impact de la dépendance liée à l’âge sur l’alimentation des personnes âgées. 32. journées annuelles de la Société française de gériatrie et gérontologie (SFGG)

Masters of their own time? Working carers’s visions about combining retirement and caring

2011

How do working careers anticipate the timing of retirement and the weight of care commitments related to other activities when retired? This question is discussed by analysing the experiences of Finnish working careers. Most of the interviewees indicated that helping parent(s) would be part of their own retirement, but after leaving full-time work they would also like to devote time for their other personal interests, too. Working careers are willing to engage in caring when retired. However, they also have a desire to outline their caring tasks and manage their own time. nonPeerReviewed

Le plaisir à manger en EHPAD : point de vue du senior consommateur

2016

Revue; Le plaisir à manger en EHPAD : point de vue du senior consommateur. journée d'études ALIMS

Les déterminants d'un apport protéique faible chez les personnes âgées

2017

National audience

Goût et préférences du consommateur âgé

2017

Revue; Goût et préférences du consommateur âgé. Sixième journée mondiale de la déglutition :

Ageing behaviour and analytical characterization of the Jatobá resin collected from Hymenaea stigonocarpa Mart.

2009

Abstract This paper reports the results of an analytical study to characterize the trunk resin collected from the Hymenaea stigonocarpa Mart. species from the region of Minas Gerais (Brazil), popularly known as Jatoba resin. Hymenaea resins are reported to have been used in artistic applications such as protective varnishes in polychromed sculptures and paintings. Therefore, the identification of the main chemical changes that take place in the resin when it is prepared as a thin film exposed to atmospheric effects have been considered herein. Changes due to the degradation effect of light have been studied on a series of specimens prepared as a thin films and subjected to accelerated UV li…