Search results for "Agenesis"
showing 10 items of 2668 documents
Regulation of IL-12 p40 Promoter Activity in Primary Human Monocytes: Roles of NF-κB, CCAAT/Enhancer-Binding Protein β, and PU.1 and Identification o…
2001
Abstract Appropriate regulation of IL-12 expression is critical for cell-mediated immune responses. In the present study, we have analyzed the regulation of IL-12 p40 promoter activity in primary human monocytes in vivo. Accordingly, we analyzed the p40 promoter by in vivo footprinting in resting and activated primary human blood CD14+ monocytes. Interestingly, footprints at binding sites for trans-activating proteins such as C/EBP, NF-κB, and ETS were only found upon stimulation with LPS and IFN-γ. In contrast, a footprint over a purine-rich sequence at −155, termed GA-12 (GATA sequence in the IL-12 promoter), was observed in resting, but not activated, cells. Further characterization of t…
Obstetric-Neonatal Care during Birth and Postpartum in Symptomatic and Asymptomatic Women Infected with SARS-CoV-2: A Retrospective Multicenter Study
2022
Este artículo se encuentra disponible en la siguiente URL: https://www.mdpi.com/1660-4601/19/9/5482 Este artículo de investigación pertenece a la colección "COVID-19 Research". En este artículo de investigación también participan: Laura Andreu-Pejó, Cristina Martínez-Porcar, Carmen Rodríguez Gonzálvez, Patricia Torrent-Ramos, Nieves Asensio-Tomás, Yolanda Herraiz-Soler, Ramon Escuriet y Desirée Mena-Tudela. This study analyses the obstetric–neonatal outcomes of women in labour with symptomatic and asymptomatic COVID-19. A retrospective, multicenter, observational study was carried out between 1 March 2020 and 28 February 2021 in eight public hospitals in the Valencian community (Spain). The…
Impact of COVID-19 Pandemic on Children and Adolescents with Neuropsychiatric Disorders: Emotional/Behavioral Symptoms and Parental Stress.
2022
The objective of our study was to evaluate the impact of the COVID-19 pandemic on the emotional and behavioral symptoms in minors with neuropsychiatric disorders and on parental stress through a standardized neuropsychological assessment, comparing the data collected before the pandemic with those collected during the lock-down. Another goal of our study was to analyze the relationship between parental stress and behavioral/emotional symptoms in children. Our study was conducted on 383 families of patients who had already been referred at the Child Neuropsychiatry Unit of the University Hospital of Salerno for different neuropsychiatric conditions. All the parents completed two neuropsychol…
Chemical speciation of nucleotide 5′-monophosphates in the presence of biogenic amines
2001
The interaction of adenosine-, uridine-, inosine- and guanosine-5’-monophosphates with protonated ethylenediamine, putrescine, cadaverine, spermidine and spermine, was studied potentiometrically, a...
Ultrasound-assisted sequential extraction method for the evaluation of mobility of toxic elements in contaminated soils
2005
A method for the fast sequential extraction of toxic elements in contaminated soil samples using an ultrasonic water bath, followed by determination with inductively coupled plasma optical emission spectrometry (ICP-OES), was developed and compared with other methods introduced in the literature. The five-step sequential extraction (Tessier scheme) was shortened using ultrasound-assisted sequential extraction (UASE). The optimization of the five-step sequential extraction was based on the analysis of SRM 2710 using Tessiers’s method as a reference. Several extracting solutions with different sonication times and temperatures were tested in the optimization procedure. Concentrations of arsen…
Metal accumulation in sediments and benthic invertebrates in lakes of Latvia
1998
The concentrations of cadmium, lead, nickel and copper in waters, sediments (total metal concentrations and their speciation forms) and benthic macroinvertebrates in 11 lakes of Latvia were determined using atomic absorption spectroscopy. Metal concentrations in lake waters, sediments and biota were compared with water chemistry. Compared to total concentrations, metal speciation forms in sediments were better correlated with respective metal concentrations in invertebrates. Therefore, the evaluation of potential metal bioaccumulation should consider metal speciation. The mean concentrations of trace metals in benthic invertebrates in Latvia were much lower than in other countries, which ca…
Production of methylated mercury, lead, and cadmium by marine bacteria as a significant natural source for atmospheric heavy metals in polar regions
1999
Abstract Mixed and pure bacterial cultures of polar origin were incubated in model experiments under polar conditions. The releasing rates of monomethyl and dimethyl mercury (MeHg+ and Me2Hg), trimethyl lead (Me3Pb+), and monomethyl cadmium (MeCd+) were determined in dependence on the incubation time. This is the first time that methylation of cadmium by bacteria could be shown. The formation of tetramethyl and dimethyl lead (Me4Pb and Me2Pb2+) was also checked but no release of these methylated compounds was observed. The determination of methylated mercury compounds was carried out by using a purge and trap system after derivatisation of monomethyl mercury into the volatile methylethyl me…
Mineral nutrients in leaves and bast of pedunculate oak (Quercus Robur L.) at different states of defoliation
1998
Abstract Adult oaks (age > 135a) with different grade of defoliation were investigated for their mineral nutrient contents in leaves and bast. In the leaves of the trees with a defoliation of more than 60 % lower concentrations of almost all nutrients were found. No differences were found between defoliation class 1 (defoliation ≤ 25 %) and defoliation class 2 (defoliation ≤ 45 %). In all defoliation classes the mineral nutrient contents are in the normal range except the contents of magnesium, which is in the range of deficiency in all defoliation classes. The mineral contents in bast showed high concentrations of cadmium, manganese zinc, and aluminum in dead trees, and in the case of cadm…
Hepatic responses of gene expression in juvenile brown trout (Salmo trutta lacustris) exposed to three model contaminants applied singly and in combi…
2007
Chemical pollution of the aquatic environment is almost always the result of multiple rather than single toxic compounds. The possibility of separating the effects of key risk chemicals from those of others, including their joint effects, is of clear theoretical interest and high technical importance. We addressed this goal using multiple gene expression profiling in the liver of juvenile brown trout (Salmo trutta lacustris) exposed to three model chemicals (cadmium, carbon tetrachloride [CCl4], and pyrene) administered singly, in binary and trinary combinations at low acutely sublethal concentrations, and in the partial dose–response manner. Differentially expressed genes were grouped by c…
Comparing the acute response to cadmium toxicity of nauplii from different populations ofArtemia
2002
The lethal responses to cadmium of instar II nauplii from eight populations of Artemia belonging to the species Artemia franciscana, Artemia salina, Artemia persimilis, and Artemia parthenogenetica have been compared. Generalized linear models were used to fit mortality. The model indicates that there is a relationship between species, type of population, and mortality rate. The two populations of A. franciscana were the most sensitive to cadmium toxicity (median lethal concentration, LC50, of 93.3-142 mg/L), while the population of A. persimilis was the most resistant (LC50 of 284 mg/L). Differences in the phenotypic variability in each population were assessed through the slope of the mor…