Search results for "Aggregation"

Polyphenols extracted from three apple cultivars grown in Sicily: effect on k-casein aggregation

2016

THE ROLE OF HSP60 IN AMYLOID BETA PATHWAY: RELEVANCE TO ALZHEIMER’S DISEASE

Alzheimer’s disease (AD) is a devastating neurodegenerative disorder affecting more than 40 million individuals worldwide. The high number of factors triggering the onset of AD justifies the current absence of disease-modifying therapies. The involved pathological mechanisms are still elusive and, therefore, the finding of effective therapies requires further elucidation of biomolecular mechanisms controlling AD pathogenesis. Particularly, the aberrant amyloidogenic cleavage of amyloid precursor protein (APP), amyloid beta (Aβ) peptide misfolding and oligomerization, and the impairment of the protein quality control machinery are key hallmarks characterizing the onset of the disease. Furthe…

Metallic Ions Effects on the Heat-aggregation Process of b-Lactoglobulin

2007

DEMAND Project: A Proposal for a Bottom-Up Aggregation Platform

2019

In many countries, a great number of electricity market operators have developed Demand Response (DR) programs with different purposes. In this framework, load aggregation represents an important issue, linked to the potential that the coordinated management of distributed resources has on affecting power systems' operation.

Distributed Demand-Response Certification using Blockchain Technology

2021

e-Fair: Aggregation in e-Commerce for Exploiting Economies of Scale

2017

In recent years, many new and interesting models of successful online business have been developed, including competitive models such as auctions, where the product price tends to rise, and group-buying, where users cooperate obtaining a dynamic price that tends to go down. We propose the e-fair as a business model for social commerce, where both sellers and buyers are grouped to maximize benefits. e-Fairs extend the group-buying model aggregating demand and supply for price optimization as well as consolidating shipments and optimize withdrawals for guaranteeing additional savings. e-Fairs work upon multiple dimensions: time to aggregate buyers, their geographical distribution, price/quant…

Robust and Efficient Data Gathering for Wireless Sensor Networks

2006

This paper describes a new strategy for data gathering in wireless sensor networks that takes into account the need for both energy saving, typical of such networks, and for a reasonable tradeoff between robustness and efficiency. The proposed algorithm implements an efficient strategy for retransmission of lost packets by discovering alternative routes and making clever use of multiple paths when necessary; in order to do that we build upon the general framework presented in recent works, that provided a formulation of duplicate and order insensitive aggregation functions, and by taking advantage of some intrinsic characteristics of the wireless sensor networks, we exploit implicit acknowl…

An Efficient Retransmission Strategy for Data Gathering in Wireless Sensor Networks Authors

2005

This paper introduces a new strategy for data gathering in wireless sensor networks that takes into account the need for both energy saving and for a reasonable tradeoff between robustness and efficiency. The proposed algorithm implements an efficient strategy for retransmission of lost packets by discovering alternative routes and making clever use of multiple paths when necessary; in order to do that we use duplicate and order insensitive aggregation functions, and by taking advantage of some intrinsic characteristics of the wireless sensor networks, we exploit implicit acknowledgment of reception and smart caching of the data.

Information Organization and Visualization for the ALS Project

2010

This work presents the adopted methodology and the realized tools for data visualization in the Linguistic Atlas Of Sicily (ALS) Project. The ALS Project has the purpose to discovery new trends and variables to track the linguistic evolution over time and space in Sicily. The project is focused on how linguistic variables are related to social and economic aspects of the evolution of population and vice-versa. The visualization tools are a relevant aspect of the project to support decisions and disseminate results. One of the major factors is the geographic dependence of data evolution. To this aim complex set of tools has been developed: some tools are stand-alone while others are collabor…

A close connection: Alzheimer’s disease and type 2 diabetes

2012

In the recent years a growing body of evidence links insulin resistance and insulin action to neurodegenerative diseases, especially Alzheimer’s disease (AD). The importance of insulin in ageing as well as its role in cognition and other aspects of normal brain functions are well established. The hippocampus and cerebral cortex-distributed insulin and insulin receptor (IR) have been shown to be involved in brain cognitive functions. Conversely, deterioration of IR signaling is involved in agingrelated brain degeneration such as in AD and cognitive impairment in type 2 diabetes patients. Insulin administration, while maintaining euglycemia, improves memory in both healthy adults and Alzheime…