Search results for "Aging"

showing 10 items of 10496 documents

A low threshold to ECG-gated repeat CTA reduces the risk of false-positive diagnosis of type A dissection in interhospital referrals: a case series s…

2018

Angela Kornberger,1 Iris Burck,2 Hazem El Beyrouti,1 Nancy Halloum,1 Andres Beiras-Fernandez,1 Christian-Friedrich Vahl1 1Department of Cardiothoracic and Vascular Surgery, University Hospital of Johannes Gutenberg University, Mainz, Germany; 2Department of Diagnostic and Interventional Radiology, University Hospital of Johann Wolfgang Goethe University, Frankfurt am Main, Germany Background: False-positive diagnosis of acute Stanford type A aortic dissection (AAD) on computed tomography angiography (CTA) is still an issue and may lead to substantial consequences. Given that electrocardiography (ECG)-gated CTA provides greater diagnostic safety, it may be assumed that interhospital referral…

medicine.medical_specialtyStanford type A dissectionTherapeutics and Clinical Risk Managementfalse-positive diagnosisECG-gated CTA030204 cardiovascular system & hematology030218 nuclear medicine & medical imaging03 medical and health sciences0302 clinical medicinemedicinePharmacology (medical)Case Seriescardiovascular diseasesGeneral Pharmacology Toxicology and PharmaceuticsType a dissectionComputed tomography angiographyAortic dissectionChemical Health and Safetymedicine.diagnostic_testbusiness.industrymusculoskeletal neural and ocular physiologyGeneral Medicinemedicine.diseaseRadiologybusinessSafety ResearchElectrocardiographypsychological phenomena and processesCase seriesTherapeutics and Clinical Risk Management
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Familial hypercholesterolaemia is underdiagnosed and undertreated in the general population: guidance for clinicians to prevent coronary heart diseas…

2013

AIMS: The first aim was to critically evaluate the extent to which familial hypercholesterolaemia (FH) is underdiagnosed and undertreated. The second aim was to provide guidance for screening and treatment of FH, in order to prevent coronary heart disease (CHD).METHODS AND RESULTS: Of the theoretical estimated prevalence of 1/500 for heterozygous FH, <1% are diagnosed in most countries. Recently, direct screening in a Northern European general population diagnosed approximately 1/200 with heterozygous FH. All reported studies document failure to achieve recommended LDL cholesterol targets in a large proportion of individuals with FH, and up to 13-fold increased risk of CHD. Based on prev…

medicine.medical_specialtyStatinAtherosclerosis; Cardiovascular disease; Cholesterol; Coronary heart disease; Low-density lipoproteinSettore MED/09 - Medicina Internamedicine.drug_classPopulationCHILDRENFamilial hypercholesterolemiaBile acid bindingCOST-EFFECTIVENESS ANALYSIS030204 cardiovascular system & hematologyLDL-CHOLESTEROLDIAGNOSIS03 medical and health scienceschemistry.chemical_compound0302 clinical medicineEzetimibeInternal medicineDiabetes mellitusmedicineMANAGEMENT030212 general & internal medicineeducationHealth aging / healthy living Cardiovascular diseases [IGMD 5]Alirocumabeducation.field_of_studyCYTOKINE PATTERN CHANGEbusiness.industryLow-density lipoproteinmedicine.diseaseAtherosclerosisCardiovascular diseaseLomitapideDENSITY-LIPOPROTEIN APHERESIS3. Good healthASSOCIATION EXPERT PANELCoronary heart diseaseEndocrinologyCholesterolchemistryCARDIOVASCULAR-DISEASEAtherosclerosiCardiology and Cardiovascular MedicinebusinessSTATIN TREATMENTmedicine.drugEuropean Heart Journal
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Stereotactic body radiation therapy for liver oligometastases: predictive factors of local response by 18F-FDG-PET/CT

2018

Objective:To investigate metabolic parameters as predictive of local response after stereotactic body radiation therapy (SBRT) for liver-oligometastases.Methods:Inclusion criteria of the present re...

medicine.medical_specialtyStereotactic body radiation therapybusiness.industryLiver NeoplasmsHumans; Liver Neoplasms; Retrospective Studies; Treatment Outcome; Fluorodeoxyglucose F18; Positron Emission Tomography Computed Tomography; Radiopharmaceuticals; Radiosurgery; Radiology Nuclear Medicine and ImagingGeneral MedicineRadiosurgery030218 nuclear medicine & medical imaging03 medical and health sciencesTreatment Outcome0302 clinical medicineFluorodeoxyglucose F18Positron Emission Tomography Computed TomographyNuclear Medicine and Imaging030220 oncology & carcinogenesisHumansMedicineRadiology Nuclear Medicine and imagingFdg pet ctRadiologyRadiopharmaceuticalsRadiologybusinessRetrospective StudiesThe British Journal of Radiology
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Infrared thermal imaging in the diagnosis of musculoskeletal injuries: a systematic review and meta-analysis.

2014

OBJECTIVE. Musculoskeletal injuries occur frequently. Diagnostic tests using ionizing radiation can lead to problems for patients, and infrared thermal imaging could be useful when diagnosing these injuries. CONCLUSION. A systematic review was performed to determine the diagnostic accuracy of infrared thermal imaging in patients with musculoskeletal injuries. A meta-analysis of three studies evaluating stress fractures was performed and found a lack of support for the usefulness of infrared thermal imaging in musculoskeletal injuries diagnosis.

medicine.medical_specialtyStress fracturesSoft Tissue Injuriesbusiness.industryInfrared RaysPoison controlGeneral Medicinemedicine.diseaseFractures BoneRisk FactorsThermographyMeta-analysisInjury preventionThermographyMedical imagingmedicineInfrared thermal imagingPhysical therapyPrevalenceHumansRadiology Nuclear Medicine and imagingIn patientPractice Patterns Physicians'businessMuscle SkeletalAJR. American journal of roentgenology
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Vestibular compensation of otolith graviceptive dysfunction in stroke patients

2022

BACKGROUND AND PURPOSE A sensitive and frequent clinical sign of a vestibular tone imbalance is the tilt of the perceived subjective visual vertical (SVV). There are no data yet focusing on lesion location at the cortical level as a factor for predicting compensation from the tilt of the SVV. METHODS With modern voxelwise lesion behavior mapping analysis, the present study determines whether lesion location in 23 right-hemispheric cortical stroke patients with an otolith dysfunction could predict the compensation of a vestibular tone imbalance in the chronic stage. RESULTS Our statistical anatomical lesion analysis revealed that lesions of the posterior insular cortex are involved in vestib…

medicine.medical_specialtyStroke patientpathology [Otolithic Membrane]610 MedizinInsular cortexcompensationLesionOtolithic MembranePhysical medicine and rehabilitation610 Medical sciencesdiagnostic imaging [Stroke]HumansMedicinecomplications [Stroke]ddc:610StrokeOtolithCerebral CortexVestibular systemChronic stagebusiness.industryCompensation (psychology)subjective visual verticalmedicine.diseasestrokeStrokemedicine.anatomical_structureNeurologyinsular cortexpathology [Stroke]pathology [Cerebral Cortex]sense organsNeurology (clinical)medicine.symptombusinessEuropean Journal of Neurology
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New advances in radiomics of gastrointestinal stromal tumors

2020

Gastrointestinal stromal tumors (GISTs) are uncommon neoplasms of the gastrointestinal tract with peculiar clinical, genetic, and imaging characteristics. Preoperative knowledge of risk stratification and mutational status is crucial to guide the appropriate patients' treatment. Predicting the clinical behavior and biological aggressiveness of GISTs based on conventional computed tomography (CT) and magnetic resonance imaging (MRI) evaluation is challenging, unless the lesions have already metastasized at the time of diagnosis. Radiomics is emerging as a promising tool for the quantification of lesion heterogeneity on radiological images, extracting additional data that cannot be assessed b…

medicine.medical_specialtyStromal cellGastrointestinal Stromal TumorsComputed tomographyTexture analysis.Clinical applications03 medical and health sciences0302 clinical medicineMagnetic resonance imagingRadiomicsmedicineMutational statusHumansComputed tomographyGastrointestinal NeoplasmsRadiomicsmedicine.diagnostic_testbusiness.industryGastroenterologyMagnetic resonance imagingMinireviewsGeneral MedicinePrognosisClinical applicationClinical PracticeTexture analysis030220 oncology & carcinogenesisRisk stratification030211 gastroenterology & hepatologyRadiologyDifferential diagnosisGastrointestinal stromal tumorRadiomicbusinessTomography X-Ray Computed
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Su1548 Diagnosis and Management of GI Stromal Tumors by EUS-FNA: Do European and US Practices of Endosonographers Differ?

2013

medicine.medical_specialtyStromal cellbusiness.industryGastroenterologymedicineRadiology Nuclear Medicine and imagingRadiologybusinessGastrointestinal Endoscopy
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Longitudinal imaging and evaluation of SAH-associated cerebral large artery vasospasm in mice using micro-CT and angiography

2019

Longitudinal in vivo imaging studies characterizing subarachnoid hemorrhage (SAH)-induced large artery vasospasm (LAV) in mice are lacking. We developed a SAH-scoring system to assess SAH severity in mice using micro CT and longitudinally analysed LAV by intravenous digital subtraction angiography (i.v. DSA). Thirty female C57Bl/6J-mice (7 sham, 23 SAH) were implanted with central venous ports for repetitive contrast agent administration. SAH was induced by filament perforation. LAV was assessed up to 14 days after induction of SAH by i.v. DSA. SAH-score and neuroscore showed a highly significant positive correlation (rsp = 0.803, p < 0.001). SAH-score and survival showed a negative sig…

medicine.medical_specialtySubarachnoid hemorrhageBiopsy030204 cardiovascular system & hematologySeverity of Illness IndexMice03 medical and health sciences0302 clinical medicineCerebral vasospasmIn vivomedicineAnimalsVasospasm Intracranialcardiovascular diseasesMicro ctmedicine.diagnostic_testbusiness.industryLarge arteryVasospasmOriginal ArticlesX-Ray MicrotomographyCerebral ArteriesSubarachnoid Hemorrhagemedicine.diseaseImmunohistochemistrynervous system diseasesCerebral AngiographyDisease Models AnimalNeurologyAngiographyFemaleNeurology (clinical)RadiologyCardiology and Cardiovascular MedicinebusinessBiomarkers030217 neurology & neurosurgeryPreclinical imagingJournal of Cerebral Blood Flow & Metabolism
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Imaging funzionale per diffusione (DWI) e ischemia cerebrale in fase acuta: Potenzialità diagnostiche e confronto con metodiche convenzionali

1997

Stroke is the third leading cause of death and is a major cause of long-term disability. Neuroprotective treatment within a 4-hour «therapeutic window» has proved highly efficacious in reducing morbility and mortality in animal model. It is with this background that the need for emergent diagnosis and therapy of acute stroke in strongly suggested. Computed tomography (CT) shows the parenchymal changes of acute stroke too late to be helpful, and its role has been primarily to evaluate the possibility of intracerebral or subarachnoid hemorrhage. While conventional magnetic resonance (MR) imaging can demonstrate parenchymal abnormalities 4–6 hours after ischemia, newer techniques such as diff…

medicine.medical_specialtySubarachnoid hemorrhageRadiological and Ultrasound Technologymedicine.diagnostic_testbusiness.industryIschemiaInfarctionMagnetic resonance imagingmedicine.diseaseNeuroprotection030218 nuclear medicine & medical imaging03 medical and health sciences0302 clinical medicineAnimal modelmedicineRadiology Nuclear Medicine and imagingcardiovascular diseasesNeurology (clinical)RadiologybusinessStroke030217 neurology & neurosurgeryCause of deathRivista di Neuroradiologia
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2020

Background: Computed tomography angiography (CTA) is frequently used with computed tomography perfusion imaging (CTP) to evaluate whether endovascular vasospasm treatment is indicated for subarachnoid hemorrhage patients with delayed cerebral ischemia. However, objective parameters for CTA evaluation are lacking. In this study, we used an automated, investigator-independent, digital method to detect vasospasm, and we evaluated whether the method could predict the need for subsequent endovascular vasospasm treatment. Methods: We retrospectively reviewed the charts and analyzed imaging data for 40 consecutive patients with subarachnoid hemorrhages. The cerebrovascular trees were digitally rec…

medicine.medical_specialtySubarachnoid hemorrhagemedicine.diagnostic_testReceiver operating characteristicbusiness.industryIschemiaVasospasmmedicine.diseasenervous system diseases030218 nuclear medicine & medical imaging03 medical and health sciences0302 clinical medicineCerebral vasospasmNeurologymedicine.arterycardiovascular systemmedicineComputed Tomography Perfusion Imagingcardiovascular diseasesNeurology (clinical)Radiologybusiness030217 neurology & neurosurgeryCircle of WillisComputed tomography angiographyFrontiers in Neurology
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