Search results for "AlON"

showing 10 items of 799 documents

Malondialdehyde in early phase of acute pancreatitis

2011

Aims: to assess oxidative stress in acute pancreatitis, its evolution over time and its relationship with the severity of the disease. Methods: during a two-year period, patients with acute pancreatitis with less than 24 hours of pain were evaluated. Serum was obtained the first, second and fourth day from admittance, if complications were detected, and after recovery. Malondialdehyde was determined by high performance liquid chromatography. Twenty healthy volunteers constituted the control group. Malondialdehyde between groups was compared with Mann-Whitney and Kruskal-Wallis tests; malondialdehyde evolution was studied with Wilcoxon test. Results: one hundred and sixty-nine patients were …

AdultMaleComplicationsmedicine.disease_causeSeverity of Illness Indexchemistry.chemical_compoundMalondialdehydeHealthy volunteersHumansMedicineProspective StudiesChromatography High Pressure LiquidAgedAged 80 and overbusiness.industryGastroenterologyGeneral MedicineMiddle AgedPrognosismedicine.diseaseMalondialdehydeAcute pancreatitisOxidative StressPancreatitischemistryOxidative stressCase-Control StudiesAnesthesiaAcute DiseaseDisease ProgressionAcute pancreatitisPancreatitisFemalebusinessEarly phaseBiomarkersOxidative stressRevista Española de Enfermedades Digestivas
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Failure of endodontic treatment due to a palatal gingival groove in a maxillary lateral incisor with talon cusp and two root canals.

1990

A case is presented in which endodontic treatment of a maxillary lateral incisor with a talon cusp and two root canals failed following a mistaken diagnosis. What was first diagnosed as an endodontic lesion was, in all probability, a primary periodontal lesion caused by the advance of bacteria from the gingival crevice to the apex along the radicular groove between the main tooth and the talon cusp.

AdultMaleDental FistulaDentistryLesionstomatognathic systemmedicineMaxillaHumansMaxillary central incisorTooth RootGeneral DentistryPeriodontal DiseasesMaxillary lateral incisorbusiness.industryTooth AbnormalitiesDental Pulp Diseasesmedicine.diseaseApex (geometry)Root Canal TherapyIncisorstomatognathic diseasesMaxillaTalon cuspcardiovascular systemmedicine.symptomDental Pulp CavitybusinessGroove (joinery)Gingival grooveJournal of endodontics
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'Prefrontal' cognitive performance of healthy subjects positively correlates with cerebral FDOPA influx: an exploratory [18F]-fluoro-L-DOPA-PET inves…

2006

Dopamine neurotransmission influences those cognitive processes, which are generally regarded as prefrontal cortical functions. In previous positron‐emission‐tomography (PET) studies, net blood‐brain clearance of [(18)F]‐fluoro‐l‐DOPA (FDOPA) correlated with impaired cognitive performance in patients with Parkinson's disease or schizophrenia. We hypothesized that FDOPA influx also correlates with performance of cognitive tasks associated with prefrontal functioning in healthy volunteers. The net blood‐brain clearance of FDOPA (K [Formula: see text]) was mapped in a group of 11 healthy volunteers and calculated in striatal volumes‐of‐interest. The Wisconsin‐Card‐Sorting‐Test (WCST), Stroop‐T…

AdultMaleElementary cognitive taskMetabolic Clearance RateDopamineCaudate nucleusPrefrontal CortexStriatumNeuropsychological Testsbehavioral disciplines and activitiesSynaptic TransmissionBasal GangliaFunctional LateralityCognitionMesencephalonReference ValuesBasal gangliaNeural PathwaysReaction TimeHumansRadiology Nuclear Medicine and imagingPrefrontal cortexResearch ArticlesBrain MappingRadiological and Ultrasound TechnologyReceptors Dopamine D2PutamenCognitive flexibilityPutamenMiddle AgedDihydroxyphenylalanineNeurologyBlood-Brain BarrierPositron-Emission TomographyNeurology (clinical)AnatomyCaudate NucleusPsychologyNeuroscienceStroop effectHuman brain mapping
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Mitochondrial dysfunction, persistent oxidative damage, and catalase inhibition in immune cells of naïve and treated Crohnʼs disease

2009

Background: Oxidative stress is considered a potential etiological factor for Crohn's disease (CD). We characterized the reactive oxygen species (ROS) generated in immune peripheral cells of CD patients, as well as their antioxidant enzyme status and the presence of oxidative damage. In addition, mitochondrial function (ΔΨm) was analyzed to detect the possible origin of ROS. Methods: Cells were obtained from patients at the onset of disease, prior to any treatment. Experiments were repeated when patients were in clinical remission. A set of experiments was carried out in a group of CD patients in persistent morphological remission. Controls were healthy volunteers who were not receiving any…

AdultMaleMitochondrial DiseasesMitochondrionBiologyPharmacologymedicine.disease_causeInflammatory bowel diseaseAntioxidantsMonocytesNitric oxideSuperoxide dismutasechemistry.chemical_compoundCrohn DiseaseMalondialdehydemedicineHumansImmunology and AllergyLymphocytesMembrane Potential Mitochondrialchemistry.chemical_classificationReactive oxygen speciesSuperoxide DismutaseSuperoxideGastroenterologyDeoxyguanosineHydrogen PeroxideCatalaseOxidantsmedicine.diseaseOxidative Stresschemistry8-Hydroxy-2'-DeoxyguanosineCatalaseCase-Control StudiesImmunologybiology.proteinFemaleReactive Oxygen SpeciesOxidative stressGranulocytesInflammatory Bowel Diseases
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Effects of L-Carnitine L-Tartrate Supplementation on Muscle Oxygenation Responses to Resistance Exercise

2008

Previous research has shown that L-carnitine L-tartrate (LCLT) supplementation beneficially affects markers of hypoxic stress following resistance exercise. However, the mechanism of this response is unclear. Therefore, the primary purpose of this study was to determine the effects of LCLT supplementation on muscle tissue oxygenation during and after multiple sets of squat exercise. Nine healthy, previously resistance-trained men (25.2 +/- 6.years, 91.2 +/- 10.2 kg, 180.2 +/- 6.3 cm) ingested 2 g.d of LCLT or an identical placebo for 23 days in a randomized, balanced, crossover, double-blind, placebo-controlled, repeated-measures study design. On day 21, forearm muscle oxygenation was measu…

AdultMaleMuscle tissuemedicine.medical_specialtyPhysical Therapy Sports Therapy and RehabilitationProstacyclinPlaceboOxygen ConsumptionDouble-Blind MethodForearmCarnitineMalondialdehydeInternal medicinemedicineHumansOrthopedics and Sports MedicineMuscle SkeletalExerciseTartratesL-Carnitine L-TartrateCross-Over StudiesSpectroscopy Near-Infraredbusiness.industryGeneral MedicineOxygenationCrossover studySurgeryOxygenmedicine.anatomical_structureDietary SupplementsVitamin B ComplexCardiologybusinessmedicine.drugBlood drawingJournal of Strength and Conditioning Research
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Interbrain emotional connection during music performances is driven by physical proximity and individual traits.

2021

How musical emotions and the pleasure derived from music, regardless of the musical valence, can be shared between individuals is a fascinating question, and investigating it can shed light on the function of musical reward. We carried out our investigations in a natural setting during an international competition for orchestra conductors. Participants (n = 15) used a dedicated smartphone app to report their subjective emotional experiences in real time while we recorded their cerebral activity using electroencephalography and their electrodermal activity. The overall behavioral real-time behavioral ratings suggest a possible social influence on the reported and felt pleasure. The physicall…

AdultMalePleasureAdolescentmedia_common.quotation_subjectEmotional contagionMusicalElectroencephalographyGeneral Biochemistry Genetics and Molecular BiologyPleasureHistory and Philosophy of SciencemedicineNatural (music)HumansValence (psychology)DiencephalonSocial influencemedia_commonAgedmedicine.diagnostic_testGeneral NeuroscienceElectroencephalographyCoherence (statistics)Middle AgedAuditory PerceptionFemalePsychologyMusicCognitive psychologyAnnals of the New York Academy of SciencesReferences
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The pterygoid reflex in man and its clinical application

1992

A technique for eliciting and recording the stretch reflex (R) of the medial pterygoid muscle (Pter) is described. The latency was 6.9 ± 0.43 ms in 23 healthy volunteers (mean age 23.7 years) showing a side-to-side difference of 0.29 ± 0.21 ms. The PterR latencies were little shorter and side-to-side difference little greater than of the masseter reflex. Observations in 5 selected patients with small brainstem lesions suggest that the neurons of the PterR afferents form a cluster within the caudal portion of the trigeminal mesencephalic nucleus. Testing the masseter and pterygoid reflexes provides a more precise localization of small ponto-mesencephalic lesions. © 1992 John Wiley & Sons, In…

AdultMaleReflex StretchPhysiologyElectromyographyNeurological disorderCellular and Molecular NeuroscienceTrigeminal Caudal NucleusMesencephalonReference ValuesPonsPhysiology (medical)medicineHumansStretch reflexSmall brainstemAgedBrain DiseasesBlinkingmedicine.diagnostic_testMasseter Musclebusiness.industryElectrodiagnosisPterygoid MusclesMean ageAnatomyMiddle Agedmedicine.diseaseMagnetic Resonance Imagingmedicine.anatomical_structureReflexMedial pterygoid muscleFemaleNeurology (clinical)Tomography X-Ray ComputedbusinessJaw jerk reflexBrain StemMuscle & Nerve
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Olive oils high in phenolic compounds modulate oxidative/antioxidative status in men

2004

The aim of the present study was to evaluate whether olive oils high in phenolic compounds influence the oxidative/antioxidative status in humans. Healthy men (n = 12) participated in a double-blind, randomized, crossover study in which 3 olive oils with low (LPC), moderate (MPC), and high (HPC) phenolic content were given as raw doses (25 mL/d) for 4 consecutive days preceded by 10-d washout periods. Volunteers followed a strict very low-antioxidant diet the 3 d before and during the intervention periods. Short-term consumption of olive oils decreased plasma oxidized LDL (oxLDL), 8-oxo-dG in mitochondrial DNA and urine, malondialdehyde in urine (P < 0.05 for linear trend), and increased HD…

AdultMaleTime FactorsMedicine (miscellaneous)Urinemedicine.disease_causeDNA MitochondrialAntioxidantschemistry.chemical_compoundDouble-Blind MethodPhenolsMalondialdehydemedicineHumansPlant OilsPhenolsFood scienceOlive OilGlutathione PeroxidaseNutrition and DieteticsCross-Over StudiesDose-Response Relationship DrugCholesterolCholesterol HDLDeoxyguanosineMalondialdehydePostprandial PeriodDietLipoproteins LDLDose–response relationshipVegetable oilPostprandialchemistryBiochemistry8-Hydroxy-2'-DeoxyguanosineOxidation-ReductionOxidative stress
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Urinary metals and metal mixtures and oxidative stress biomarkers in an adult population from Spain: The Hortega Study

2019

Introduction: Few studies have investigated the role of exposure to metals and metal mixtures on oxidative stress in the general population. Objectives: We evaluated the cross-sectional association of urinary metal and metal mixtures with urinary oxidative stress biomarkers, including oxidized to reduced glutathione ratio (GSSG/GSH), malondialdehyde (MDA), and 8‑oxo‑7,8‑dihydroguanine (8-oxo-dG), in a representative sample of a general population from Spain (Hortega Study). Methods: Urine antimony (Sb), barium (Ba), cadmium (Cd), chromium (Cr), cobalt (Co), copper (Cu), molybdenum (Mo), vanadium (V) and zinc (Zn) were measured by ICPMS in 1440 Hortega Study participants. Results: The geomet…

AdultMaleUrine metals010504 meteorology & atmospheric sciencesPopulationchemistry.chemical_elementUrineZinc010501 environmental sciencesPopulation-basedmedicine.disease_cause01 natural scienceschemistry.chemical_compoundChromiumMetal mixturesMalondialdehydeMetals HeavymedicineHumanseducationlcsh:Environmental sciences0105 earth and related environmental sciencesGeneral Environmental ScienceAgedlcsh:GE1-350Cadmiumeducation.field_of_studyDeoxyguanosineGlutathioneMiddle AgedMalondialdehydeGlutathioneCross-Sectional Studieschemistry8-Hydroxy-2'-DeoxyguanosineSpainOxidative stressEnvironmental PollutantsFemaleOxidative stressBiomarkersNuclear chemistryEnvironment International
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Oral supplements of vitamin E improve measures of oxidative stress in plasma and reduce oxidative damage to LDL and erythrocytes in β-thalassemia int…

2001

Fifteen beta-thalassemia intermedia patients, not requiring chronic transfusional therapy, were monitored in order to check their antioxidant status, and the lipid oxidation products in plasma, LDL, and erythrocytes before and during a 9-month oral treatment with 600 mg/day vitamin E. The low level of vitamin E, and high level of malondialdehyde in plasma clearly tended to normalize after three months (P < .001), and were quite similar to control after six months. The abnormally low level of vitamin E in LDL and the four times higher than control basal level of conjugated dienes (LDL-CD), were not modified after three months of treatment. Significant changes of LDL-VE (P < .05) and of the b…

AdultMaleVitaminmedicine.medical_specialtyErythrocytesAntioxidantAdolescentmedicine.medical_treatmentAdministration OralHematocritBiochemistryAntioxidantsLipid peroxidationchemistry.chemical_compoundLipid oxidationReference ValuesInternal medicinemedicineHumansVitamin EChildVitamin Amedicine.diagnostic_testVitamin EOsmolar Concentrationbeta-ThalassemiaGeneral MedicineMiddle Agedbeta CaroteneMalondialdehydeLipidsLipoproteins LDLOxidative StressEndocrinologychemistryCase-Control StudiesFemaleHemoglobinFree Radical Research
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