Search results for "Alaria"
showing 10 items of 273 documents
Malaria, poverty and medical treatment in the district of Agrigento (1830–1836)
1998
It is kown that the destruction of woods has been the reason of the beginning of"malaria". In the Middle Age there was a lot of forests in Sicily. In the province of Agrigento malaria was already kown especially in Cammarata in 1141; in the area of Burgic in 1172; in Licata in 1398 adin the south of Girgenti (Girgenti was the ancient name of Agrigento) in 1253. Huge expenses of water determined, between 1256 and 1379, the fight against malaria. In the XV and XV1 centuries the destruction of the Sicilian forests could be said systematically begun by the landowners, that had destined the land to the production of wheat. Then, the area of Agrigento was the place where the surviving vegetation …
Chronicles of rice, mosquitoes and malaria in Spain: the case of the province of Valencia (18th-20th centuries)
2010
This study analyzes the situation of the rice fields in the Valencia province (Eastern Spain) during the centuries XVIII-XX. This area, together with the region of Campo Arañuelo (Western Spain), is one of the territories with highest malaria prevalence during the Spain's Modern History. Medical, demographic, social, economic and legal issues related with the problematic of the rice during this epoch are also discussed. Furthermore, this article provides information about the supposed transmission mechanisms of the disease, as well as the fight against it through chemotherapeutic and environmental sanitation techniques.
Functional Signatures of Human CD4 and CD8 T Cell Responses to Mycobacterium tuberculosis
2014
With 1.4 million deaths and 8.7 million new cases in 2011, tuberculosis (TB) remains a global health care problem and together with HIV and Malaria represents one of the three infectious diseases world-wide. Control of the global TB epidemic has been impaired by the lack of an effective vaccine, by the emergence of drug-resistant forms of Mycobacterium tuberculosis (Mtb) and by the lack of sensitive and rapid diagnostics. It is estimated, by epidemiological reports, that one third of the world's population is latently infected with Mtb, but the majority of infected individuals develop long-lived protective immunity, which controls and contains Mtb in a T cell-dependent manner. Development o…
Sentencia del Tribunal Constitucional n.º 112/2017, de 16 de octubre [BOE n.º 256, 24-X-2017]
2018
Sentencia del Tribunal Constitucional n.º 112/2017, de 16 de octubre [BOE n.º 256, 24-X-2017]
Artemisinin–Second Career as Anticancer Drug?
2015
Artemisinin represents a showcase example not only for the activity of medicinal herbs deriving from traditional chinese medicine, but for phytotherapy in general. Its isolation from Sweet Wormwood (qinhao, Artemisia annua L.) represents the starting point for an unprecedent success story in the treatment of malaria worldwide. Beyond the therapeutic value against Plasmodium parasites, it turned out in recent years that the bioactivity of artemisinin is not restricted to malaria. We and others found that this sesquiterpenoid also exerts profound anticancer activity in vitro and in vivo. Artemisinin-type drugs exert multi-factorial cellular and molecular actions in cancer cells. Ferrous iron …
Evaluation of the efficacy of a new insecticide paint against malaria vectors
2015
La malaria continúa siendo un problema de salud pública global. Se calcula que en el mundo hay 3.300 millones de personas en 97 países y territorios que corren el riesgo de padecer el paludismo, y que para 1.200 millones ese riesgo es elevado (WHO, 2014). El control de la malaria a gran escala está altamente basado en al control del vector, principalmente mediante el uso de mosquiteras tratadas con insecticidas de larga duración (LLINs), y en menor medida, el Rociamiento Residual Intradomiciliario. Todos los tratamientos recomendados de LLINs y la mayoría del Rociamiento Residual Intradomiciliario se basan en el uso de piretroides. La creciente resistencia de los vectores de malaria a los p…
El pensament etiològic microbià i el paludisme (1880-1900)
2001
S'estudia l'evolució etiològica sobre el paludisme des de 1880 a 1990. Els vint anys estudiats permeten comprovar que la teoria miasmàtica que interpretava l'origen del paludisme va deixar pas a l'explicació microbiana causal sense a penes un altre canvi que la identificació del miasma palúdic amb l'hematozou de Laveran. Només el descobriment del mosquit anòfel com a vector de transmissió del paràsit va fer que se substituís la via respiratòria per la inoculació cutània com a mecanisme d'infecció. L’aire dels pantans no era ja el perjudicial, sinó les seues aigües estancades, el lloc on es criaven les larves dels mosquits, l'eliminació dels quals va convertir-se en el centre de la lluita an…
Advances of Research in Education and ICT in Hospital Classrooms
2017
Últimamente ha proliferado la utilización de aplicaciones didácticas digitales en torno a la educación del alumnado convaleciente. No obstante, son escasos los trabajos que han estudiado de forma global las tecnologías de la información y la comunicación (TIC) y sus materiales en las aulas hospitalarias (AH). Desde ese punto de vista, hemos realizado un análisis de los avances alcanzados en las investigaciones desarrolladas sobre experiencias educativas, evaluando el impacto de las TIC y comprobando que el alumnado hospitalizado puede conectarse con la comunidad educativa y su entorno. La metodología llevada a cabo ha sido la revisión bibliográfica que nos ha permitido organizar, clasificar…
Data from: Continental-scale patterns of pathogen prevalence: a case study on the corncrake
2014
Pathogen infections can represent a substantial threat to wild populations, especially those already limited in size. To determine how much variation in the pathogens observed among fragmented populations is caused by ecological factors, one needs to examine systems where host genetic diversity is consistent among the populations, thus controlling for any potentially confounding genetic effects. Here, we report geographic variation in haemosporidian infection among European populations of corncrake. This species now occurs in fragmented populations, but there is little genetic structure and equally high levels of genetic diversity among these populations. We observed a longitudinal gradient…
A systematic review on the efficacy and safety of chloroquine for the treatment of COVID-19
2020
Purpose COVID-19 (coronavirus disease 2019) is a public health emergency of international concern. As of this time, there is no known effective pharmaceutical treatment, although it is much needed for patient contracting the severe form of the disease. The aim of this systematic review was to summarize the evidence regarding chloroquine for the treatment of COVID-19. Methods PubMed, EMBASE, and three trial Registries were searched for studies on the use of chloroquine in patients with COVID-19. Results We included six articles (one narrative letter, one in-vitro study, one editorial, expert consensus paper, two national guideline documents) and 23 ongoing clinical trials in China. Chloroqui…