Search results for "Alkylphenols"

Multigram Scale Enzymatic Synthesis of (R)-1-(4′-Hydroxyphenyl)ethanol Using Vanillyl Alcohol Oxidase

2018

The enantioselective oxyfunctionalisation of C−H bonds is a highly interesting reaction, as it provides access to chiral alcohols that are important pharmaceutical building blocks. However, it is hard to achieve using traditional methods. One way in which it can be achieved is through the action of oxidative enzymes. Although many reports of the oxyfunctionalisation capabilities of enzymes at an analytical scale have been published, reports on the use of enzymes to achieve oxyfunctionalisation on a synthetically relevant scale are fewer. Here, we describe the scale-up of the conversion of 4-ethylphenol to (R)-1-(4′-hydroxyphenyl)ethanol using the flavin-dependent enzyme vanillyl alcohol oxi…

Occupational exposure to endocrine disruptors and lymphoma risk in a multi-centric European study

2015

Background: Incidence rates of lymphoma are usually higher in men than in women, and oestrogens may protect against lymphoma. Methods: We evaluated occupational exposure to endocrine disrupting chemicals (EDCs) among 2457 controls and 2178 incident lymphoma cases and subtypes from the European Epilymph study. Results: Over 30 years of exposure to EDCs compared to no exposure was associated with a 24% increased risk of mature B-cell neoplasms (P-trend=0.02). Associations were observed among men, but not women. Conclusions: Prolonged occupational exposure to endocrine disruptors seems to be moderately associated with some lymphoma subtypes. © 2015 Cancer Research UK. All rights reserved.

Micropollutants removal in an anaerobic membrane bioreactor and in an aerobic conventional treatment plant

2012

The paper expresses an attempt to tackle the problem due to the presence of micropollutants in wastewater which may be able to disrupt the endocrine system of some organisms. These kinds of compounds are ubiquitously present in municipal wastewater treatment plant (WWTP) effluents. The aim of this paper is to compare the fate of the alkylphenols-APs (4-(tert-octyl)) phenol, t-nonylphenol and 4-p-nonylphenol and the hormones (estrone, 17ß-estradiol and 17¿-ethinylestradiol) in a submerged anaerobic membrane bioreactor (SAMBR) pilot plant and in a conventional activated sludge wastewater treatment plant (CTP). The obtained results are also compared with the results obtained in a previous stud…

Metody wydzielania, zatężania i oznaczania związków fenolowych z próbek środowiskowych i żywności

2011

Determination of phenolic compounds in surface waters using high-performance liquid chromatography and molecularly imprinted solid-phase extraction

2021

An effective and reliable analytical method based on molecularly imprinted solid-phase extraction (MI-SPE) and high-performance liquid chromatography with photodiode array detector was developed to simultaneously determine four phenolic compounds: bisphenol A, 2-phenylphenol, tert-octylphenol and nonylphenol. A molecularly imprinted polymer that can selectively recognize bisphenol A and alkylphenols was developed. A bulk polymerization method using bisphenol A as a template, acrylamide as functional monomer, ethylene glycol dimethacrylate as the cross-linking agent, acetonitrile as porogenic solvent and 1,1’-azobis(cyclohexanecarbonitrile) as initiator was applied. This polymer was applied …