Search results for "Aloin"
showing 10 items of 16 documents
New national and regional bryophyte records, 51
2017
1. Aloina rigida (Hedw.) Limpr.Contributors: O. Yu. Pisarenko, V. E. Fedosov and V. A. BakalinRussia: Primorsky Territory, Dalnegorsky District, vicinity of Dalnegorsk Town, NE-facing steep slope o...
Increased illumination levels enhance biosynthesis of aloenin A and aloin B in Aloe arborescens Mill., but lower their per-plant yield
2021
Abstract Leaves of Aloe arborescens Mill. are a relevant source of secondary metabolites of pharmaceutical relevance. Notwithstanding, specialized cultivations of A. arborescens are still rather limited, and a straightforward agronomical research addressed to the obtainment of high-quality material is lacking. With the purpose to fill this gap, from 2016 to 2018, a trial was arranged to evaluate the growth and development of A. arborescens, along with the production of four active metabolites (aloin A and B, aloenin A, and isoaloeresin D) with varying some growth conditions. Two growth substrates (“A”- a commercial substrate, and “B”- the same substrate + 20 % perlite), two durations of pre…
Enteric Aloin loaded microparticles for treatment of colorectal cancer
2008
Aloin loaded matrix tablets for topical treatment of oral cancer
2008
Mucoadhesive Polymeric Films to Enhance Barbaloin Penetration Into Buccal Mucosa: a Novel Approach to Chemoprevention.
2018
Nowadays, chemoprevention by administering natural supplements is considered an attractive strategy to reverse, suppress, or prevent the evolution of premalignant oral lesions. In particular, Barbaloin exhibits anti-proliferative, anti-inflammatory, and anti-cancer properties, and it results useful in multi-therapy with classic chemotherapeutics. Therefore, in this work, mucoadhesive buccal films, as locoregional drug delivery system able to provide a targeted and efficient therapeutic delivery of Barbaloin, are proposed. Thus, Aloin extract-loaded Eudragit (R) RL100 or Eudragit (R) RS100-based buccal films were designed in order to obtain an easily self-administrable formulation capable of…
Changes of species specific cuticular hydrocarbon profiles in the cockroaches Nauphoeta cinerea and Leucophaea maderae reared in heterospecific groups
1997
0013-8703 (Print) 1570-7458 (Online); The cuticular hydrocarbon profiles of the cockroaches Nauphoeta cinerea and Leucophaea maderae are species-specific when maintained in homospecific rearings. When individuals were reared in mixed species colonies, they initially remained in homospecific groups under different shelters. However, after 14 days they formed one heterospecific group with cuticular profiles showing characteristics of both species. When individuals were returned in monospecific rearings, their cuticular hydrocarbon profiles returned to species-specific ones within 3 weeks.
Aloin delivery on buccal mucosa: ex vivo studies and design of a new locoregional dosing system
2014
Context: Chemoprevention of potential malignant disorders or cancerous lesions that affect oral mucosae requires extended duration of treatment. Locoregional delivery of natural products could represent a promising strategy for this purpose. Objective: To investigate the aptitude of aloin to permeate through, or accumulate in, the buccal mucosa and to develop a new prolonged oro-mucosal drug delivery system. Materials and Methods: Permeation/accumulation of aloin from Curacao Aloe (containing 50% barbaloin) was evaluated ex vivo, using porcine buccal mucosa as the most useful model to simulate human epithelium. Oro-mucosal matrix tablets were prepared by dispersing aloin (10% w/w) in Eudrag…
Umbilical cord blood transplantation from unrelated donors in patients with Philadelphia chromosome-positive acute lymphoblastic leukemia
2014
Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't; There are very few disease-specific studies focusing on outcomes of umbilical cord blood transplantation for Philadelphia chromosome-positive acute lymphoblastic leukemia. We report the outcome of 45 patients with Philadelphia chromosome-positive acute lymphoblastic leukemia who underwent myeloablative single unit cord blood transplantation from unrelated donors within the GETH/GITMO cooperative group. Conditioning regimens were based on combinations of thiotepa, busulfan, cyclophospamide or fludarabine, and antithymocyte globulin. At the time of transplantation, 35 patients (78%) were in first complete remission, four (8%) …
Efecto de los factores de crecimiento derivados de las plaquetas en la reparación de defecto óseo cortical
2015
El Plasma Rico en Plaquetas Puro (P-PRP), es un concentrado plaquetario fácilmente disponible para liberar factores de crecimiento a partir de las plaquetas y mejorar la cicatrización del tejido musculo-esquelético. Esta tecnología, no está exenta de controversia, ya que numerosos autores obtienen beneficio en el tratamiento de trastornos de tejidos blandos, en cambio este efecto beneficioso en la consolidación ósea, reparación de fracturas recalcitrantes o regeneración tisular no está tan claro. La gran variabilidad de métodos de preparación y condiciones distintas de uso, proporcionan un alto riesgo de realizar un uso incorrecto o no apropiado.. El objetivo de este trabajo es el estudio d…