Search results for "Alpi"

showing 10 items of 159 documents

Plants assemble species specific bacterial communities from common core taxa in three arcto-alpine climate zones

2017

Evidence for the pivotal role of plant-associated bacteria to plant health and productivity has accumulated rapidly in the last years. However, key questions related to what drives plant bacteriomes remain unanswered, among which is the impact of climate zones on plant-associated microbiota. This is particularly true for wild plants in arcto-alpine biomes. Here, we hypothesized that the bacterial communities associated with pioneer plants in these regions have major roles in plant health support, and this is reflected in the formation of climate and host plant specific endophytic communities. We thus compared the bacteriomes associated with the native perennial plants Oxyria digyna and Saxi…

0301 basic medicineMicrobiology (medical)PH030106 microbiologyDIVERSITYBiologySaxifraga oppositifoliaMicrobiologyActinobacteriabiogeographical diversity03 medical and health sciencesarcto-alpine plantBotanyGRADIENTMICROBIAL COMMUNITIESOxyria digynaOriginal Research2. Zero hungerOxyria digynaSaxifraga oppositifoliaPioneer speciesSEQUENCESEcologyfungiAlpine climatefood and beveragesRHIZOSPHERE15. Life on landENDOPHYTIC BACTERIAbiology.organism_classificationcore bacteriomeTUNDRABurkholderialesendophytic bacteria030104 developmental biologySOIL TYPEta1181ProteobacteriaAcidobacteriaBIOGEOGRAPHYFrontiers in Microbiology
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Strong regionality and dominance of anaerobic bacterial taxa characterize diazotrophic bacterial communities of the arcto-alpine plant species Oxyria…

2017

Arctic and alpine biomes are most often strongly nitrogen-limited, and hence biological nitrogen fixation is a strong driver of these ecosystems. Both biomes are characterized by low temperatures and short growing seasons, but they differ in seasonality of solar radiation and in soil water balance due to underlying permafrost in the Arctic. Arcto-alpine plant species are well-adapted to the low temperatures that prevail in their habitats, and plant growth is mainly limited by the availability of nutrients, in particular nitrogen, due to slow mineralization. Nitrogen fixing bacteria are likely important for plant growth in these habitats, but very little is known of these bacteria or forces …

0301 basic medicineMicrobiology (medical)endofyytitAlpine plantlcsh:QR1-502TUSSOCK TUNDRASaxifraga oppositifoliaMicrobiologylcsh:MicrobiologyCHINACARBON03 medical and health sciencesBotanyNIFH GENEDominance (ecology)Oxyria digynaOriginal Research2. Zero hungerClostridiumRhizospherePioneer speciesbiologynifHEcologySHRUBSta1183food and beverages15. Life on landbiology.organism_classificationNITROGEN-FIXING BACTERIASOILendophytic bacteria030104 developmental biologymikrobistoArctic13. Climate actiontypensidontaNitrogen fixationta1181GeobacterHIGH DIVERSITYpioneer plantsFrontiers in Microbiology
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Cytotoxicity of seven naturally occurring phenolic compounds towards multi-factorial drug-resistant cancer cells

2016

Abstract Introduction In medical oncology, multi-drug resistance (MDR) of cancer cells continues to be a major impediment. We are in quest of novel anti-proliferative agents to overcome drug-resistant tumor cells. Methods In the present study, we investigated the cytotoxicity of 7 naturally occurring phenolic compounds including two isoflavonoids alpinumisoflavone ( 1 ) and laburnetin ( 2 ), one biflavonoid amentoflavone ( 3) , three lignans pycnanthulignene A ( 4 ), pycnanthulignene B ( 5 ), and syringaresinol ( 7 ) and one xanthone, euxanthone ( 6 ) against 9 drug-sensitive and MDR cancer cell lines. The resazurin reduction assay was used to evaluate the cytotoxicity of these compounds, w…

0301 basic medicineSyringaresinolPharmaceutical SciencePharmacologyAmentoflavone03 medical and health scienceschemistry.chemical_compound0302 clinical medicinePhenolsIsoflavonoidCell Line TumorNeoplasmsOxazinesDrug DiscoveryHumansCytotoxic T cellCytotoxicityMembrane Potential MitochondrialPharmacologyCell Cycle CheckpointsAlpinumisoflavoneAntineoplastic Agents PhytogenicDrug Resistance MultipleEnzyme Activation030104 developmental biologyXanthenesComplementary and alternative medicinechemistryDrug Resistance NeoplasmApoptosisCaspases030220 oncology & carcinogenesisCancer cellMolecular MedicineReactive Oxygen SpeciesPhytomedicine
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Evaluation of DNA Methylation Episignatures for Diagnosis and Phenotype Correlations in 42 Mendelian Neurodevelopmental Disorders

2020

Contains fulltext : 218274.pdf (Publisher’s version ) (Closed access) Genetic syndromes frequently present with overlapping clinical features and inconclusive or ambiguous genetic findings which can confound accurate diagnosis and clinical management. An expanding number of genetic syndromes have been shown to have unique genomic DNA methylation patterns (called "episignatures"). Peripheral blood episignatures can be used for diagnostic testing as well as for the interpretation of ambiguous genetic test results. We present here an approach to episignature mapping in 42 genetic syndromes, which has allowed the identification of 34 robust disease-specific episignatures. We examine emerging pa…

0301 basic medicine[SDV]Life Sciences [q-bio]Computational biology030105 genetics & heredityBiologyPediatricsArticleCohort Studiesmolecular diagnostics03 medical and health sciencessymbols.namesakeGenetic HeterogeneityGene duplicationGeneticsHumansHunter-McAlpine syndromeGenetics (clinical)Mass screening030304 developmental biologyEpiSignGenetics0303 health sciencesNeurodevelopmental disorders Donders Center for Medical Neuroscience [Radboudumc 7]DNA methylationGenetic heterogeneity030305 genetics & heredityCorrectionSyndromeDNA MethylationMolecular diagnosticsPhenotypePenetranceHuman genetics3. Good healthepisignaturegenomic DNA030104 developmental biologyPhenotypeNeurodevelopmental DisordersDNA methylationuncertain clinical casesMendelian inheritancesymbolsIdentification (biology)VUS classification
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Risk-reducing hysterectomy and bilateral salpingo-oophorectomy in female heterozygotes of pathogenic mismatch repair variants: a Prospective Lynch Sy…

2021

Abstract Purpose To determine impact of risk-reducing hysterectomy and bilateral salpingo-oophorectomy (BSO) on gynecological cancer incidence and death in heterozygotes of pathogenic MMR ( path_MMR ) variants. Methods The Prospective Lynch Syndrome Database was used to investigate the effects of gynecological risk-reducing surgery (RRS) at different ages. Results Risk-reducing hysterectomy at 25 years of age prevents endometrial cancer before 50 years in 15%, 18%, 13%, and 0% of path_MLH1 , path_MSH2 , path_MSH6 , and path_PMS2 heterozygotes and death in 2%, 2%, 1%, and 0%, respectively. Risk-reducing BSO at 25 years of age prevents ovarian cancer before 50 years in 6%, 11%, 2%, and 0% and…

0301 basic medicinemedicine.medical_treatmentDNA Mismatch RepairGynecologic surgery0302 clinical medicineMalalties hereditàriesProspective StudiesProspective cohort studyGenetics (clinical)Mismatch Repair Endonuclease PMS2Incidence (epidemiology)Middle Aged16. Peace & justiceLynch syndrome3. Good health030220 oncology & carcinogenesisFemalesyöpätauditMutL Protein Homolog 1Genetic diseasesHeterozygotemedicine.medical_specialtySalpingo-oophorectomyCirurgia ginecològicaHysterectomyArticle03 medical and health sciencesCàncer colorectalCAPP2medicineHumansLynchin oireyhtymäGynecologyperinnölliset tauditHysterectomyHEREDITARY COLORECTAL-CANCERbusiness.industryEndometrial cancerCancermedicine.diseaseColorectal Neoplasms Hereditary NonpolyposisColorectal cancerASPIRIN030104 developmental biologyClinical researchLynch syndrome3121 General medicine internal medicine and other clinical medicinekohdunpoisto3111 BiomedicineOvarian cancerbusiness
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The aspect of nationality and performance in a mountain ultra-marathon-the ‘Swiss Alpine Marathon’

2012

Eichenberger E, Knechtle B, Rust CA, Lepers R, Rosemann T, Onywera VO. The aspect of nationality and performance in a mountain ultra-marathon - the ‘Swiss Alpine Marathon’ J. Hum. Sport Exerc. Vol. 7, No. 4, pp. 748-762, 2012. Runners from East Africa and especially from Kenya dominate middle- and longdistance running races worldwide. The aim of the present study was to investigate the participation and performance trends regarding the nationality of runners in a mountain ultra-marathon held in partially high alpine terrain. We hypothesized that Kenyan runners, living and training in the Great Rift Valley, a predominantly hilly, mountainous and altitudinous region like the Alps, would domin…

11035 Institute of General PracticeKenyaAlpine ultra-runningEthnic groupPhysical Therapy Sports Therapy and Rehabilitation610 Medicine & healthUltra marathonGeographyHumEast africaEthnicityEducación Física y DeportivaNationalitylcsh:Sports medicine3612 Physical Therapy Sports Therapy and Rehabilitationlcsh:RC1200-1245SocioeconomicsUltra enduranceEndurance runningUltra endurance
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Soil moisture variations from boreal forests to the tundra

2023

Soil moisture has a profound influence on life on Earth, and this vital water resource varies across space and time. Here, we explored soil moisture variations in boreal forest and tundra environments, where comprehensive soil moisture datasets are scarce. We installed soil moisture sensors up to 14 cm depth at 503 measurement sites within seven study areas across northern Europe. We recorded 6,138,528 measurements to capture soil moisture variations of the snowless season from April to September 2020. We described the spatio-temporal patterns of soil moisture, and test how these patterns are linked to topography and how these links vary in space and time. We found large spatial variation a…

4112 ForestrymaaperäkosteusSoil waterWetlandSoil wetnessSubarcticAlpinemetsätWater Science and Technologymittausmenetelmät
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Alpu kreimules herbāriji Latvijas Universitātes Muzejā

1922

Alpu kreimule Pinguicula alpina L. ir rets augs, kurš šobrīd vairs nav sastopams Latvijas flora. Tā vienīgā dabīgā augtene bija uz Staburaga Daugavas krastā. Pļaviņu HES būvniecibas rezultātā tā tika iznīcināta. Latvijas Universitātes Muzeja herbārijā Botānikas un mikoloģijas kolekcijās glabājas šā auga herbāriji gan no Latvijas, gan Igaunijas. Šeit atrodas gan senākais ievāktais herbārijs uz Staburaga, gan pēdējais, kas tika šeit ievākts 1961. gadā.

:NATURAL SCIENCES::Biology [Research Subject Categories]alpu kreimuleherbārijsalpu taucenebotany:HUMANITIES and RELIGION::History and philosophy subjects::History subjects::History of science [Research Subject Categories]Staburagsledus laikmeta reliktsPinguicula alpina L.
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Анализ результатов интродукции альпийских растений в Ботаническом саду Латвийского Университета

2016

Анализ успешности интродукции некоторых альпийских растений в течении 50 лет. Работа проводилась с 136 таксонами в Ботаническом саду Латвийского Университета. (Материалы VII Международной научной конференции. 24-26 мая 2016, Минск, Белорусь.)

:NATURAL SCIENCES::Biology [Research Subject Categories]альпийские растнияAlpine plantsтравянистые многолетникиperennial herbal plantsalpu augi
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Abundance of narG , nirS , nirK , and nosZ Genes of Denitrifying Bacteria during Primary Successions of a Glacier Foreland

2006

ABSTRACT Quantitative PCR of denitrification genes encoding the nitrate, nitrite, and nitrous oxide reductases was used to study denitrifiers across a glacier foreland. Environmental samples collected at different distances from a receding glacier contained amounts of 16S rRNA target molecules ranging from 4.9 × 10 5 to 8.9 × 10 5 copies per nanogram of DNA but smaller amounts of narG , nirK , and nosZ target molecules. Thus, numbers of narG , nirK , nirS , and nosZ copies per nanogram of DNA ranged from 2.1 × 10 3 to 2.6 × 10 4 , 7.4 × 10 2 to 1.4 × 10 3 , 2.5 × 10 2 to 6.4 × 10 3 , and 1.2 × 10 3 to 5.5 × 10 3 , respectively. The densities of 16S rRNA genes per gram of soil increased with…

ALPINE DEVELOPMENTDNA BacterialglacierNitrite ReductasesDenitrificationNitrogenDenitrification pathwayDIVERSITYBiologyNitrate ReductasePolymerase Chain ReactionApplied Microbiology and BiotechnologyCOLONIZATIONMicrobial EcologyDenitrifying bacteriaRNA Ribosomal 16SBotanyIce CoverMICROBIAL COMMUNITIESGlacier forelandPoaPrimary successionEcosystemSoil Microbiology[SDV.EE]Life Sciences [q-bio]/Ecology environmentRhizosphereBacteriaBase SequenceEcologyRHIZOSPHEREQUANTIFICATIONNitrite reductaseSOILSRNA BacterialGenes BacterialAustriaOxidoreductasesSoil microbiologyFood ScienceBiotechnologyApplied and Environmental Microbiology
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