Search results for "Alter"

Critical Appraisal of Scientific Articles

2009

Despite the increasing number of scientific publications, many physicians find themselves with less and less time to read what others have written. Selection, reading, and critical appraisal of publications is, however, necessary to stay up to date in one’s field. This is also demanded by the precepts of evidence-based medicine (1, 2). Besides the medical content of a publication, its interpretation and evaluation also require understanding of the statistical methodology. Sadly, not even in science are all terms always used correctly. The word "significance," for example, has been overused because significant (or positive) results are easier to get published (3, 4). The aim of this article …

Topical cyclosporine as an alternative treatment for herpetic interstitial keratitis

2010

New rules on driver licensing for patients with obstructive sleep apnea: European Union Directive 2014/85/EU

2016

Editorial, no abstract

A study of hurdles in mass treatment of schistosomiasis in KwaZulu-Natal, South Africa

2015

Background: It has been estimated that 700 million people worldwide and 5.2 million people in South Africa are in need of annual treatment for schistosomiasis. In accordance with the current policy the Department of Health (DoH) in KwaZulu-Natal province, South Africa, aimed to reach 75% treatment coverage in a mass treatment campaign (MTC) of schools in a schistosomiasis-endemic area.Methods: A cross-sectional study was designed to explore the implementation, coverage, challenges and limitations of a DoH MTC in a middle-income country. The study was conducted by exploring nurses’ and research team records, school enrolment lists and parental consent forms.Results: Slightly more than 10 000…

The causes of low adherence in patients with antihypertensive therapy

2016

Low adherence to antihypertensive therapy is a major cause of adverse cardiovascular outcomes by uncontrolled high blood pressure. If the most frequent causes of inappropriate taking of medicine are identified, possible improvements within the health care could be performed, promoting the safety and efficacy of antihypertensive therapy. The aim was to find the factors affecting patient's adherence during antihypertensive therapy. In the period from June to September 2014 a quantitative study was carried out including patients with diagnosed arterial hypertension who visited pharmacies in Riga to get the antihypertensive therapy. The study collected data of 152 patients with the mean antihyp…

On the Randomisation Gallery:Random Reflections on a Popular Method in Medical Research

2016

Objective: Randomized controlled trials (RCTs) and meta-analysis are increasingly utilized methods in medicine. There is, however, substantial critique on both from the theoretical as well as from the practical side. Methods: Seven points on RCTs and three on meta-analysis were choosen to summarize the current critique. Studies critically reviewing the quality of meta-analyses in various fields of medicine were narratively reviewed. Results: The typical RCT is short, performed on a small group of selected patients without severe comorbidity. It is expensive and favors drugs over other forms of therapies. Furthermore, neither patients nor doctors much like RCTs, they feel restricted in their…

Obstructive Sleep Apnea and Snoring

2017

Moderate-to-severe sleep-disordered breathing (SDB) is common in the general population, particularly between ages 50 and 70. Obstructive sleep apnea (OSA) is a major public health concern presenting a high associated risk for hypertension, cardiovascular disease, type II diabetes, and motor vehicle accidents. The dentist should always evaluate for the presence of risk factors in patients with any signs of SDB. PSG is the gold standard for the diagnosis of OSA and sleep disorders. The CPAP device is still considered the most effective therapeutic approach for the management of SDB in both adults and children; however, their side effects and low adherence make clinicians look for alternative…

The efficacy of muscle energy techniques in symptomatic and asymptomatic subjects: a systematic review

2019

Abstract Background Muscle energy techniques are applied to reduce pain and increase range of motion. These are applied to a variety of pathological conditions and on asymptomatic subjects. There is however limited knowledge on their effectiveness and which protocol may be the most beneficial. Objective The aim of this review is to determine the efficacy of muscle energy techniques (MET) in symptomatic and asymptomatic subjects. Design Systematic Review. Methods A literature search was performed using the following database: Cochrane Library, MEDLINE, NLM Pubmed and ScienceDirect. Studies regarding MET in asymptomatic and symptomatic patients were considered for investigation. The main outc…

Building bridges: future directions for medical error disclosure research.

2013

Abstract Objective The disclosure of medical errors has attracted considerable research interest in recent years. However, the research to date has lacked interdisciplinary dialog, making translation of findings into medical practice challenging. This article lays out the disciplinary perspectives of the fields of medicine, ethics, law and communication on medical error disclosure and identifies gaps and tensions that occur at these interdisciplinary boundaries. Methods This article summarizes the discussion of an interdisciplinary error disclosure panel at the 2012 EACH Conference in St. Andrews, Scotland, in light of the current literature across four academic disciplines. Results Current…

Diagnostische Möglichkeiten und Behandlungsstrategien für die Fraktur der Eminentia intercondylica im Wachstumsalter

1995

Between 1970 and 1993 29 fractures of the intercondylar eminence were seen in children with almost the same number of cases showing no or minor displacement as those requiring open reduction for major dislocation. Combined knee injury must be suspected the higher the patient's age and the more pronounced the displacement of the fragment. Magnetic resonance imaging (MRI) has gained diagnostic predominance. Arthroscopy remains important for surgical management, especially of associated meniscus and cartilage damage. Early puncture of hemarthrosis is essential. Closed management is the therapy for nondisplaced fragments or those with bone contact or only tuberculum fractures--while displaced f…