Search results for "Alter"

showing 10 items of 2368 documents

Choosing wisely: Practical considerations on treatment efficacy and safety of asthma in the elderly

2015

The prevalence of asthma in the most advanced ages is similar to that of younger ages. However, the concept that older individuals may suffer from allergic asthma has been largely denied in the past, and a common belief attributes to asthma the definition of "rare" disease. Indeed, asthma in the elderly is often underdiagnosed or diagnosed as COPD, thus leading to undertreatment of improper treatment. This is also due to the heterogeneity of clinical and functional presentations of geriatric asthma, including the partial loss of reversibility and the lower occurrence of the allergic component in this age range. The older asthmatic patients are also characterized the coexistence of comorbid …

Allergymedicine.medical_specialtyAgingAllergyImmunologyAlternative medicineDiseaseReviewSettore MED/10 - Malattie Dell'Apparato RespiratorioAging; Allergy; Asthma; TherapymedicineImmunology and AllergyIntensive care medicineMolecular BiologyNon pharmacologicalAsthma...COPDbusiness.industryAging; Allergy; Asthma; Therapy; Molecular Biology; Immunology and Allergy; ImmunologySettore MED/09 - MEDICINA INTERNAmedicine.diseaseTreatment efficacyAsthmarespiratory tract diseasesClinical trialImmunologyTherapybusiness
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Residents'corner February 2014. Editorial: What's new this month?

2014

In this issue of the EJD, two articles shed light on sun-tanning behaviour in southern Europe [1, 2] that will be discussed here. We also critically review an article by Stockfleth et al. [4] who propose the ‘maximum lesion count’ as a new parameter for efficacy assessment of field-directed therapy for actinic keratoses. Last but not least, the publication of Mailhol et al. [5] on food allergies in children with atopic dermatitis will be reviewed.Skin cancer prevention is an important aspect [...]

Allergymedicine.medical_specialtyCancer preventionintegumentary systembusiness.industryAlternative medicineDermatologyAtopic dermatitisActinic keratosesmedicine.diseaseDermatologySkin DiseasesLesion countMedicineHumansbusinessEuropean journal of dermatology : EJD
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Cellular stress induces cap-independent alpha-enolase/MBP-1 translation.

2015

AbstractMyc promoter-binding protein-1 (MBP-1) is a shorter protein variant of the glycolytic enzyme alpha-enolase. Although several lines of evidence indicate that MBP-1 acts as a tumor suppressor, the cellular mechanisms and signaling pathways underlying MBP-1 expression still remain largely elusive. To dissect these pathways, we used the SkBr3 breast cancer cell line and non-tumorigenic HEK293T cells ectopically overexpressing alpha-enolase/MBP-1. Here, we demonstrate that induced cell stresses promote MBP-1 expression through the AKT/PERK/eIF2α signaling axis. Our results contribute to shedding light on the molecular mechanisms underlying MBP-1 expression in non-tumorigenic and cancer c…

Alpha-enolaseCellEukaryotic Initiation Factor-2Alternative translationBiochemistryeIF-2 KinaseBreast cancerHEK293 CellStructural BiologyProtein IsoformsbiologyMedicine (all)Translation (biology)Recombinant ProteinEndoplasmic Reticulum StressRecombinant ProteinsNeoplasm ProteinsDNA-Binding ProteinsGene Expression Regulation Neoplasticmedicine.anatomical_structureFemaleSignal transductionMyc promoter-binding protein-1Breast NeoplasmHumanSignal TransductionCell SurvivalDNA-Binding ProteinRecombinant Fusion ProteinsBiophysicsBreast NeoplasmsNeoplasm ProteinGeneticCell Line TumorEndoplasmic reticulum streGeneticsmedicineBiomarkers TumorHumansGene SilencingMolecular BiologyProtein kinase BTumor Suppressor ProteinTumor Suppressor ProteinsHEK 293 cellsProtein IsoformCell BiologySettore BIO/18 - GeneticaHEK293 CellsBiophysicGene Expression RegulationPhosphopyruvate HydrataseCancer cellbiology.proteinUnfolded protein responseCancer researchProto-Oncogene Proteins c-aktRecombinant Fusion ProteinFEBS letters
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Psicología de los afectados por el VIH/SIDA

2002

En este artículo se describen las alteraciones emocionales más frecuentes en las perso¬nas afectadas por el VIH. Ante los posibles cambios generados por la infección se des¬criben las alteraciones depresivas y de ansiedad y los temores.También se describen pautas de intervención para trabajar las alteraciones e instru¬mentos para intervenir sobre la aceptación de la nueva situación en personas.

Alteraciones emocionales Comportamientos depresivos Cogniciones sobre el Sida Factores indicativos de riesgo Trastornos neurológicos Áreas de intervención.:PSICOLOGÍA::Psicofarmacología [UNESCO]:PSICOLOGÍA [UNESCO]UNESCO::PSICOLOGÍAUNESCO::PSICOLOGÍA::Psicofarmacología
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Gravi alterazioni su olivo in Sicilia causate da Phoma incompta Sacc. et Mart.

2005

Alterazione olivo Phoma incompta
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L'opacità abbagliante di Dio.Sull'ermeneutica diacritica del divino di Richard Kearney

2014

Phenomenological philosophy of religion (Söderblom, van der Leeuw and Otto at the beginning) stresses the impossibility of a conceptual definition of God and considers the sacred as the very object of religion. The sacred is an oxymoronic reality, because it is at the same time opaque and glaring, in the sense that it escapes an eidetic objectifying intuition, but is felt in the body in an immediate and also upsetting way. As Richard Kearney shows, on the level of feeling through the body subjectivity works on the Otherness, which is the phenomenon of its carnal Erlebnis, activating hermeneutical diacritical operations thanks to the role of imagination and under the condition of confidence …

Alterità ermeneutica fenomenologia delle religioni sacro.Settore M-FIL/01 - Filosofia Teoretica
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Alternanza scuola-lavoro: gli studenti e il processo decisionale

2018

La capacità decisionale è da sempre considerata fondamentale perché oltre ad essere esercitata nella vita quotidiana, risulta particolarmente importante nella scelta professionale. I giovani devono prendere delle decisioni professionali molte volte durante la propria vita; formare a queste competenze è uno dei compiti principali della scuola. Il contributo presenta un’indagine esplorativa che ha come oggetto lo sviluppo del processo decisionale degli studenti di scuola secondaria che svolgono percorsi di Alternanza scuola-lavoro. L’attività di ricerca ha coinvolto 516 studenti di scuola secondaria di secondo grado delle province di Palermo e Agrigento nell’a.s. 2016/2017.

Alternanza scuola-lavoro decision making indagine esploraticaSettore M-PED/04 - Pedagogia Sperimentale
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Mycotoxin Profile and Phylogeny of Pathogenic Alternaria Species Isolated from Symptomatic Tomato Plants in Lebanon

2021

The tomato is one of the most consumed agri-food products in Lebanon. Several fungal pathogens, including Alternaria species, can infect tomato plants during the whole growing cycle. Alternaria infections cause severe production and economic losses in field and during storage. In addition, Alternaria species represent a serious toxicological risk since they are able to produce a wide range of mycotoxins, associated with different toxic activities on human and animal health. Several Alternaria species were detected on tomatoes, among which the most important are A. solani, A. alternata, and A. arborescens. A set of 49 Alternaria strains isolated from leaves and stems of diseased tomato plant…

Alternaria arborescens0106 biological sciencesVeterinary medicineHealth Toxicology and MutagenesisAlternariolAlternaria mali morpho-speciesmultilocus gene sequencingToxicology<i>Alternaria mali</i> morpho-species01 natural sciencesAlternaria alternataArticletoxigenic fungi03 medical and health scienceschemistry.chemical_compoundSolanum lycopersicumPhylogeneticsotorhinolaryngologic diseasesTenuazonic acidGenetic variabilityLebanonMycotoxinPhylogenyPlant Diseases030304 developmental biology0303 health sciencesbiologyStrain (biology)RAlternariafood and beveragesMycotoxins<i>Alternaria alternata</i>biology.organism_classificationAlternariachemistryFruit<i>Alternaria arborescens</i>Alternaria alternataMedicine010606 plant biology & botanyToxins
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Benign Nocturnal Alternating Hemiplegia Of Childhood: A New Case.

2009

Alternating Hemiplegia childhood
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A marching-on in time meshless kernel based solver for full-wave electromagnetic simulation

2012

A meshless particle method based on an unconditionally stable time domain numerical scheme, oriented to electromagnetic transient simulations, is presented. The proposed scheme improves the smoothed particle electromagnetics method, already developed by the authors. The time stepping is approached by using the alternating directions implicit finite difference scheme, in a leapfrog way. The proposed formulation is used in order to efficiently overcome the stability relation constraint of explicit schemes. In fact, due to this constraint, large time steps cannot be used with small space steps and vice-versa. The same stability relation holds when the meshless formulation is applied together w…

Alternating directions implicit scheme · Finite difference time domain · Meshless methods · Electromagnetic transient analysisRegularized meshless methodElectromagneticsApplied MathematicsNumerical analysisMathematical analysisFinite-difference time-domain methodSolverSettore ING-IND/31 - ElettrotecnicaSettore MAT/08 - Analisi NumericaKernel (image processing)Meshfree methodsApplied mathematicsTime domainMathematicsNumerical Algorithms
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