Search results for "Altera"

Establishment and Preliminary Characterization of Three Astrocytic Cells Lines Obtained from Primary Rat Astrocytes by Sub-Cloning.

2020

Gliomas are complex and heterogeneous tumors that originate from the glial cells of the brain. The malignant cells undergo deep modifications of their metabolism, and acquire the capacity to invade the brain parenchyma and to induce epigenetic modifications in the other brain cell types. In spite of the efforts made to define the pathology at the molecular level, and to set novel approaches to reach the infiltrating cells, gliomas are still fatal. In order to gain a better knowledge of the cellular events that accompany astrocyte transformation, we developed three increasingly transformed astrocyte cell lines, starting from primary rat cortical astrocytes, and analyzed them at the cytogenet…

Post-mortem alteration of diet-related enamel surface textures through artificial biostratinomy: A tumbling experiment using mammal teeth

2019

In the fossil record, teeth are often all that remains of a fossil organism. Dental microwear texture analysis (DMTA) is a common proxy for diet using dental wear features at the μm-scale, enabling comparative and quantitative assessments of various feeding traits in extant and extinct species. In extinct species, original diet-related dental wear features may be overprinted by post-mortem alteration including fluvial transport. Here we experimentally investigate the effects of mechanical alteration on diet-related 3D enamel surface texture (3DST) patterns of different mammal teeth. Post canine teeth of Equus sp., Capreolus capreolus and Otomys sp. are tumbled in sediment-water suspensio…

Emergence of ovulatory cycles with aging in women with polycystic ovary syndrome (PCOS) alters the trajectory of cardiovascular and metabolic risk fa…

2013

Abstract STUDY QUESTION: What alters cardiovascular and metabolic risk factors with aging in women with polycystic ovary syndrome (PCOS)? SUMMARY ANSWER: Lipid parameters, mainly low-density lipoprotein (LDL) cholesterol, increase with aging, but not in women who attain ovulatory cycles. WHAT IS KNOWN ALREADY: Cardiovascular and metabolic parameters tend to increase with aging, but this has not been shown in a prospective longitudinal study in women with PCOS. Correlates of these changes have not been identified. STUDY DESIGN: A prospective cohort of 118 hyperandrogenic women with PCOS who were followed from the age of 20-25 years at 5 year intervals for 20 years. PARTICIPANTS/MATERIALS, SE…

Recombinations of chromosomal bands 10q24, 12q14-q15, and 14q24 in two cases of pulmonary chondroid hamartoma studied by fluorescence in situ hybridi…

2003

Abstract Pulmonary chondroid hamartomas (PCH) are benign mesenchymal tumors consisting of at least two cytogenetic subgroups. These subgroups are defined by chromosomal alterations at either 12q14∼q15 or 6p21. Cytogenetic analysis of short-term cultures from two PCHs revealed two different rearrangements with 12q14∼q15. One of these had a unique translocation t(12;14)(q14∼15;q24) with presence of two normal chromosomes 12 and a der(14), but missing the der(12). The other showed a complex rearrangement between chromosomes 10 and 12 with two different derivatives. Our data have been confirmed with fluorescence in situ hybridization analysis. These cases represent variant forms of the standard…

An Online Observational Study of Patients With Olfactory and Gustory Alterations Secondary to SARS-CoV-2 Infection

2020

Introduction: Since the beginning of the Covid-19 epidemic produced by SARS2-Cov virus, olfactory alterations have been observed at a greater frequency than in other coronavirus epidemics. While olfactory alterations may be observed in patients with rhinovirus, influenza virus, or parainfluenza virus infection, they are typically explained by nasal obstruction with mucus or direct epithelial damage; in the case of SARS-CoV-2, olfactory alterations may present without nasal congestion with mucus. We performed a study of patients presenting olfactory/gustatory alterations in the context of SARS-CoV-2 infection in order to contribute to the understanding of this phenomenon. Material and Method…

Psicología de los afectados por el VIH/SIDA

2002

En este artículo se describen las alteraciones emocionales más frecuentes en las perso¬nas afectadas por el VIH. Ante los posibles cambios generados por la infección se des¬criben las alteraciones depresivas y de ansiedad y los temores.También se describen pautas de intervención para trabajar las alteraciones e instru¬mentos para intervenir sobre la aceptación de la nueva situación en personas.

Gravi alterazioni su olivo in Sicilia causate da Phoma incompta Sacc. et Mart.

2005

Cribado de alteraciones visuales (parte 2)

2015

En el presente trabajo se revisan y actualizan las recomendaciones de PrevInfad sobre el cribado de alteraciones visuales en la infancia. Se analizan los beneficios en salud de la deteccion precoz, la validez y seguridad de las pruebas de cribado, la efectividad del tratamiento y los posibles riesgos de la deteccion precoz y el tratamiento de los problemas detectados. PrevInfad recomienda incluir la inspeccion ocular y la prueba del reflejo rojo en las visitas de salud de los primeros seis meses de vida, asi como la deteccion de alteraciones visuales (ambliopia, estrabismo y errores de refraccion) a la edad de 3-5 anos. La evidencia para evaluar el balance entre los beneficios y los riesgos…

Cribado de alteraciones visuales (parte 1)

2014

En el presente trabajo se revisan y actualizan las recomendaciones de PrevInfad sobre el cribado de alteraciones visuales en la infancia. Se analizan los beneficios en salud de la deteccion precoz, la validez y seguridad de las pruebas de cribado, la efectividad del tratamiento y los posibles riesgos de la deteccion precoz y el tratamiento de los problemas detectados. PrevInfad recomienda incluir la inspeccion ocular y la prueba del reflejo rojo en las visitas de salud de los primeros seis meses de vida, asi como la deteccion de alteraciones visuales (ambliopia, estrabismo y errores de refraccion) a la edad de 3-5 anos. La evidencia para evaluar el balance entre los beneficios y los riesgos…

specific inflammatory response of Anemonia sulcata (cnidaria) after bacterial injection cause tissue rejection and enzymatic activity alteration

2015

The evolution of multicellular organisms was marked by adaptation to protect against pathogens. The mechanisms for discriminating the ''self'' from ''non-self” have evolved into a long history of cellular and molecular strategies from damage repair to the co-evolution of host-pathogen interaction. The phylum of Cnidaria is one of the first branches in the tree of animal life to provide crucial insights on the evolution of immunity. Sea anemones (Anthozoa, Cnidaria) are benthic sessile species able to maintain the integrity of the tissues and allorecognition in colonial forms and to differentiate between symbionts and pathogenic intruders. We investigated the inflammatory response in sea ane…