Search results for "Ambientale"

showing 10 items of 2499 documents

Chemical Composition, In Vitro Antitumor and Pro-Oxidant Activities of Glandora rosmarinifolia (Boraginaceae) Essential Oil

2018

The biological properties of essential oils have been demonstrated in the treatment of several diseases and to enhance the bioavailability of other drugs. In natural habitats the essential oils compounds may play important roles in the protection of the plants as antibacterials, antivirals, antifungals, insecticides and also against herbivores by reducing their appetite for such plants or by repelling undesirable others. We analyzed by gas-chromatography mass spectrometry the chemical composition of the essential oil of aerial parts of Glandora rosmarinifolia (Ten.) D.C. Thomas obtained by hydrodistillation and verified some biological activities on a panel of hepatocellular carcinoma cell …

0301 basic medicineChemical RadicalsAntioxidantmedicine.medical_treatmentMDA-MB-231Cancer Treatmentlcsh:MedicinenaphthoquinoneChemical CompositionBiochemistryPhysical ChemistryditerpeneAntioxidantslaw.invention0302 clinical medicinelawBreast TumorsSUM 149Medicine and Health SciencesBioassaySettore BIO/15 - Biologia FarmaceuticaCytotoxicitylcsh:ScienceMultidisciplinarybiologyTraditional medicineChemistryLiver DiseasesBoraginaceaeBoraginaceaeOxidantsHep3BLipidsChemistryOncology030220 oncology & carcinogenesisPhysical SciencesResearch ArticleHepG2Free RadicalsCell SurvivalGastroenterology and HepatologyCarcinomas03 medical and health sciencesInhibitory Concentration 50Cell Line TumorAromatic HydrocarbonsGastrointestinal TumorsBreast CancermedicineOils VolatileHumansPlant OilsEssential oilcytotoxic activityHA22T/VGH; HepG2; Hep3B; SUM 149; MDA-MB-231; cytotoxic activity; diterpenes; naphthoquinones; plant secondary metabolitesVolatile Organic CompoundsDose-Response Relationship DrugCell growthPlant ExtractsHA22T/VGHlcsh:RChemical CompoundsBiology and Life SciencesCancers and NeoplasmsEpithelial CellsHepatocellular CarcinomaSettore CHIM/06 - Chimica OrganicaPlant Components Aerialbiology.organism_classificationPro-oxidantplant secondary metabolitesAntineoplastic Agents PhytogenicHydrocarbonsBioavailability030104 developmental biologySettore BIO/03 - Botanica Ambientale E ApplicataHepatocytesSettore BIO/14 - Farmacologialcsh:QOils
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Bacterial community structure and removal performances in IFAS-MBRs: A pilot plant case study

2017

Abstract The paper reports the results of an experimental campaign carried out on a University of Cape Town (UCT) integrated fixed-film activated sludge (IFAS) membrane bioreactor (MBR) pilot plant. The pilot plant was analysed in terms of chemical oxygen demand (COD) and nutrients removal, kinetic/stoichiometric parameters, membrane fouling and sludge dewaterability. Moreover, the cultivable bacterial community structure was also analysed. The pilot plant showed excellent COD removal efficiency throughout experiments, with average value higher than 98%, despite the slight variations of the influent wastewater. The achieved nitrification efficiency was close to 98% for most of the experimen…

0301 basic medicineEnvironmental EngineeringNitrogenIFAS-MBR010501 environmental sciencesManagement Monitoring Policy and LawBiologyWastewaterMembrane bioreactor01 natural sciencesWaste Disposal Fluid03 medical and health sciencesBioreactorsMBBRWaste Management and Disposal0105 earth and related environmental sciencesWWTPBiological nutrients removal; Enhanced biological phosphorus removal; IFAS-MBR; MBBR; Membrane bioreactors; WWTP; Environmental EngineeringSewageSettore ICAR/03 - Ingegneria Sanitaria-AmbientaleMembrane foulingChemical oxygen demandEnvironmental engineeringGeneral MedicinePulp and paper industryBiological nutrients removalNitrification030104 developmental biologyActivated sludgeEnhanced biological phosphorus removalPilot plantWastewaterDenitrificationEnhanced biological phosphorus removalMembrane bioreactorNitrification
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Population Structure in the Model Grass Brachypodium distachyon Is Highly Correlated with Flowering Differences across Broad Geographic Areas

2016

The small, annual grass Brachypodium distachyon (L.) Beauv., a close relative of wheat (Triticum aestivum L.) and barley (Hordeum vulgare L.), is a powerful model system for cereals and bioenergy grasses. Genome-wide association studies (GWAS) of natural variation can elucidate the genetic basis of complex traits but have been so far limited in B. distachyon by the lack of large numbers of well-characterized and sufficiently diverse accessions. Here, we report on genotyping-by-sequencing (GBS) of 84 B. distachyon, seven B. hybridum, and three B. stacei accessions with diverse geographic origins including Albania, Armenia, Georgia, Italy, Spain, and Turkey. Over 90,000 high-quality single-nu…

0301 basic medicineGermplasmLinkage disequilibriumlcsh:QH426-470PopulationPlant Sciencelcsh:Plant cultureQuantitative trait locusBiologyphenology03 medical and health sciencesGeneticGenetic variationevolutionGeneticslcsh:SB1-1110educationbiogeographyeducation.field_of_studyEcologySettore BIO/02 - Botanica Sistematicafood and beveragespopulation structureVernalizationbiology.organism_classificationBrachypodium distachyon genome DNA Poaceae Population structurelcsh:Genetics030104 developmental biologyEvolutionary biologySettore BIO/03 - Botanica Ambientale E ApplicataBrachypodium distachyonAgronomy and Crop ScienceReference genome
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The genomic history of Southern Europe

2018

Farming was first introduced to southeastern Europe in the mid-7th millennium BCE - brought by migrants from Anatolia who settled in the region before spreading throughout Europe. However, the dynamics of the interaction between the first farmers and the indigenous hunter-gatherers remain poorly understood because of the near absence of ancient DNA from the region. We report new genome-wide ancient DNA data from 204 individuals-65 Paleolithic and Mesolithic, 93 Neolithic, and 46 Copper, Bronze and Iron Age-who lived in southeastern Europe and surrounding regions between about 12,000 and 500 BCE. We document that the hunter-gatherer populations of southeastern Europe, the Baltic, and the Nor…

0301 basic medicineMaleHistorySteppe01 natural sciencesgenome wide ancient DNA0302 clinical medicinepopulation dynamicsComputingMilieux_MISCELLANEOUSHistory Ancient2. Zero hunger0303 health scienceseducation.field_of_studyMultidisciplinarygeography.geographical_feature_categoryFarmersGenomeAgricultureCline (biology)GenomicsGrasslandEuropeGeographyWestern europeEthnologyFemalesoutheastern EuropeHumanArchaeogenetics010506 paleontologyAsia[SHS.ARCHEO]Humanities and Social Sciences/Archaeology and PrehistoryHuman MigrationPopulationPopulationSettore BIO/08 - AntropologiaIndigenousArticleAncient03 medical and health sciencesgenetic variation ; genomics ; prehistoric Europe ; prehistoric archeology ; bioarchaeologyBioarchaeologygenomicsGeneticsHumansHUMANISTIC SCIENCES. Archeology.FarmerDNA AncientSex DistributioneducationMesolithic030304 developmental biology0105 earth and related environmental sciencesHUMANISTIČKE ZNANOSTI. Arheologija.Extramuralbusiness.industryGenome HumanAmbientaleDNAArchaeologyPRIRODNE ZNANOSTI. Biologija. Genetika evolucija i filogenija.genome wide ancient DNA; southeastern Europe; population dynamics030104 developmental biologyAncient DNAGenetics PopulationAgriculturegenetic variationAgriculture; Asia; DNA Ancient; Europe; Farmers; Female; Genetics Population; Genome Human; Grassland; History Ancient; Human Migration; Humans; Male; Sex Distribution; GenomicsAncient DNA Genomics Southeastern Europe Genetic VariationbusinessNATURAL SCIENCES. Biology. Genetics Evolution and Phylogenetics.030217 neurology & neurosurgery
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Protein misfolding, amyotrophic lateral sclerosis and guanabenz: Protocol for a phase II RCT with futility design (ProMISe trial)

2017

IntroductionRecent studies suggest that endoplasmic reticulum stress may play a critical role in the pathogenesis of amyotrophic lateral sclerosis (ALS) through an altered regulation of the proteostasis, the cellular pathway-balancing protein synthesis and degradation. A key mechanism is thought to be the dephosphorylation of eIF2α, a factor involved in the initiation of protein translation. Guanabenz is an alpha-2-adrenergic receptor agonist safely used in past to treat mild hypertension and is now an orphan drug. A pharmacological action recently discovered is its ability to modulate the synthesis of proteins by the activation of translational factors preventing misfolded protein accumula…

0301 basic medicineOncologyPathologyamyotrophic lateral sclerosisamyotrophic lateral sclerosis; motor neurone disease; neuromuscular disease; randomized clinical trial guanabenz; unfolded protein response; adrenergic alpha-2 receptor agonist s; age of onset; amyotrophic lateral sclerosis; disease progression; double-blind method; endoplasmic reticulum stress; guanabenz; humans; italy; medical futility; neuroprotective agents; proteostasis deficienciesamyotrophic lateral sclerosis; motor neurone disease; neuromuscular disease; randomized clinical trial guanabenz; unfolded protein response; Medicine (all)randomized clinical trial guanabenzHelsinki declaration0302 clinical medicineProtocolAdrenergic alpha-2 Receptor Agonists1506Amyotrophic lateral sclerosisAge of OnsetGuanabenzMedicine (all)amyotrophic lateral sclerosis; motor neurone disease; neuromuscular disease; randomized clinical trial guanabenz; unfolded protein responseNeurodegenerationamyotrophic lateral sclerosis; motor neurone disease; neuromuscular disease; randomized clinical trial guanabenz; unfolded protein response;amyotrophic lateral sclerosis; guanabenz; motor neurone disease; neuromuscular disease; randomized clinical trial; unfolded protein response; Adrenergic alpha-2 Receptor Agonists; Age of Onset; Amyotrophic Lateral Sclerosis; Disease Progression; Double-Blind Method; Endoplasmic Reticulum Stress; Guanabenz; Humans; Italy; Medical Futility; Neuroprotective Agents; Proteostasis DeficienciesGeneral Medicineunfolded protein responseEndoplasmic Reticulum StressRiluzoleNeuroprotective AgentsNeurologyTolerabilityItalyDisease Progression1713GuanabenzMedical Futilitymedicine.drugmedicine.medical_specialtyamyotrophic lateral sclerosis; motor neurone disease; neuromuscular disease; randomized clinical trial guanabenz; unfolded protein response; Adrenergic alpha-2 Receptor Agonists; Age of Onset; Amyotrophic Lateral Sclerosis; Disease Progression; Double-Blind Method; Endoplasmic Reticulum Stress; Guanabenz; Humans; Italy; Medical Futility; Neuroprotective Agents; Proteostasis Deficiencies; Medicine (all)Neuroprotection03 medical and health sciencesmotor neurone diseaseDouble-Blind MethodInternal medicinemedicineHumansProteostasis Deficienciesbusiness.industryAmbientaleneuromuscular diseaserandomized clinical trialmedicine.diseaseClinical trial030104 developmental biologybusiness030217 neurology & neurosurgery
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Pursuing softer urban mobility behaviors through game-based apps

2020

Cities are currently engaged through their urban policies in pushing people towards less environmentally impacting mobility modalities: therefore, cycling and walking are strongly promoted, especially by means of new and wider limited traffic and no-cars zones. In this paper, the effectiveness of the new smartphones and apps-based technologies in modifying the mobility behaviors of citizens towards more sustainable choices has been investigated. Specifically, the potential of a smartphone app, directly involving citizens by means of a game rewarding the most sustainable trips, has been tested on a university commuters' group. These latter, starting from their current mobility situation, wer…

0301 basic medicineUrban energy consumptionInformation sciencePsychological interventionEnvironmental pollution7. Clean energyArticleInformation scienceEnvironmental pollutionEnvironmental science03 medical and health sciences0302 clinical medicineEnvironmental analysi11. SustainabilityClimate changelcsh:Social sciences (General)lcsh:Science (General)Environmental analysisGame-based appMultidisciplinaryModalitiesSettore ING-IND/11 - Fisica Tecnica AmbientaleUrban policyEnvironmental economicsCommuter030104 developmental biology13. Climate actionClimate policySweet mobilitySmartphone appAir qualityTRIPS architectureGame basedlcsh:H1-99Smartphone030217 neurology & neurosurgeryCommuterslcsh:Q1-390Heliyon
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Ethnobotanical uses of wild taxa as galactagogues in Sicily (Italy)

2018

<p>Breastfeeding furnishes optimal nutrition, immune support, and a multitude of health benefits to mothers and newborns. Since ancient times plants have been employed as galactagogues in the folk medicine of many human cultures. In Sicily, a region with great floristic diversity in the Mediterranean area, where a conspicuous pool of species is traditionally used for food and aromatic, cosmetic, handicraft, agricultural, forestry, and medicinal purposes, some people recognize the galactagogue properties of some spontaneous plants.</p><p>The goal of this study was to identify wild plants with galactagogue properties and vegetable-food remedies traditionally used by women du…

0301 basic medicinebreastfeedingethnobotanical investigationsBreastfeedingPlant ScienceFloristicsSettore BIO/01 - Botanica Generale03 medical and health sciences0302 clinical medicineHandicraftlcsh:BotanyMadonie territoryphytoestrogensTraditional medicinebiologybusiness.industrySettore BIO/02 - Botanica Sistematicagalactagogue plantsgalactagogue plantGalactagogueAsteraceaebiology.organism_classificationlcsh:QK1-989Ethnobotanical investigation030104 developmental biologyGeographyTaxonAgriculture030220 oncology & carcinogenesisEthnobotanySettore BIO/03 - Botanica Ambientale E ApplicataPhytoestrogenbusinessActa Societatis Botanicorum Poloniae
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Effect of a co-substrate supply in a MBR treating shipboard slop: Analysis of hydrocarbon removal, biomass activity and membrane fouling tendency

2018

The paper reports the main results of an experiment carried out on a membrane bioreactor (MBR) plant designed for the treatment of shipboard slops. With a view of a co-treatment process of the slop with other wastewaters, sodium acetate, as external co-substrate, was supplied (high dosage – Period 1, low dosage – Period 2) to evaluate its effects on hydrocarbons removal. The MBR pilot plant enabled approximately 99% of total petroleum hydrocarbon (TPH) removal during the entire experiment, confirming the robustness of the MBR technology for the treatment of slops. The chromatography/mass spectrometry analysis showed that the removal efficiency for each alkane was close to the value observed…

0301 basic medicinechemistry.chemical_classificationEnvironmental EngineeringSettore ICAR/03 - Ingegneria Sanitaria-AmbientaleChemistryMembrane foulingBiomedical EngineeringBioengineeringBiomass kinetics Co-substrate Diesel fuel hydrocarbons Gas chromatography/mass spectrometry MBR010501 environmental sciencesBiodegradationMembrane bioreactorPulp and paper industry01 natural sciences03 medical and health scienceschemistry.chemical_compound030104 developmental biologyActivated sludgeHydrocarbonPilot plantTotal petroleum hydrocarbonSodium acetate0105 earth and related environmental sciencesBiotechnologyBiochemical Engineering Journal
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Biotechnology a Source of Knowledge in Agreement with Green Strategies for the Conservation of Cultural Assets

2019

In this study, conservative strategies are applied in order to limit any irreversible damage and to characterize and quantify microbial colonization that may induce the deterioration of constitutive heritage materials; subsequently, suitable antimicrobial interventions are performed based on the use of biotechnology. This paper presents a summary of the basic and applied biotechnology research developed in the Laboratory of Biology and Biotechnology for Cultural Heritage (LaBBCH, University of Palermo, Italy). It shows that biotechnology has an evidently important role in the preservation and restoration of cultural assets, also taking into consideration that “Prevention is better than cure…

0301 basic medicinegreen biocidelcsh:NX1-820biodeterioration; integrated approach; bioactive molecules; green biocide030106 microbiologybiodeterioration integrated approach bioactive molecules green biocide.010501 environmental scienceslcsh:Arts in general01 natural sciencesintegrated approach03 medical and health sciencesbioactive moleculesSettore BIO/03 - Botanica Ambientale E Applicatabiodeterioration0105 earth and related environmental sciencesConservation Science in Cultural Heritage
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Old sleeping Sicilian beauty: seed germination in the palaeoendemic Petagnaea gussonei (Spreng.) Rauschert (Saniculoideae, Apiaceae).

2015

Petagnaea gussonei (Apiaceae) is a perennial herbaceous species endemic to northeast Sicily (Nebrodi Mountains). It is considered a remnant of the Sicilian Tertiary flora, and is endangered according to the Red List. There is no information in the literature about the germinability of its seeds, even though seed production is know to occur. The aim of this study was to obtain data to better understand seed germination of this species and its biological implications. Thus, several approaches were employed: vitality analyses, gibberellic acid supply, germination and soil microbial flora analyses via end-point and qPCR. The results suggest that seed germination occurs after ca. 1.5 years at a …

16S genePerennial plantEndangered speciesSaniculoideaeGerminationPlant Sciencechemistry.chemical_compoundPlant Growth RegulatorsBotanyIUCN Red ListPetagnaea gussoneisoil microbial floraGibberellic acidEcology Evolution Behavior and SystematicsSoil MicrobiologybiologySeed dormancyseed dormancyfood and beveragesGeneral Medicinebiology.organism_classificationPlant DormancyPetagnaeaBotanical GardenGibberellinschemistryGerminationSettore BIO/03 - Botanica Ambientale E ApplicataThreatened speciesSeedsITSreal-time PCRApiaceaePlant biology (Stuttgart, Germany)
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