Search results for "Amebicides"

showing 2 items of 2 documents

Effect of antiretroviral protease inhibitors alone, and in combination with paromomycin, on the excystation, invasion and in vitro development of Cry…

2003

With the spread of the human immunodeficiency virus in the early 1980s, cryptosporidiosis was regarded as an AIDS-defining disease. As an opportunistic pathogen, the intestinal parasite Cryptosporidium parvum became an important cause of chronic diarrhoea, leading to high morbidity and mortality in immunocompromised patients. To date, no effective chemotherapy is available. With the introduction of protease inhibitors (PIs) in highly active antiretroviral therapy (HAART), the incidence of cryptosporidiosis in AIDS patients has declined substantially in western countries. We have therefore tested the effect of five PIs used in HAART on the excystation, invasion and development of the parasit…

Microbiology (medical)Cell SurvivalParomomycinvirusesCryptosporidiosisParomomycinHost-Parasite InteractionsMicrobiologyImmunoenzyme Techniquesimmune system diseasesIndinavirAntiretroviral Therapy Highly ActiveCell Line TumormedicineAnimalsHumansPharmacology (medical)Protease inhibitor (pharmacology)AmebicidesAntibacterial agentCryptosporidium parvumPharmacologybiologyvirus diseasesDrug SynergismHIV Protease Inhibitorsbiochemical phenomena metabolism and nutritionbiology.organism_classificationVirologyInfectious DiseasesCryptosporidium parvumNelfinavirRitonavirSaquinavirmedicine.drugJournal of Antimicrobial Chemotherapy
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Early Diagnosis of Acanthamoeba Infection during Routine Cytological Examination of Cerebrospinal Fluid

2006

ABSTRACT Early identification of Acanthamoeba in cerebrospinal fluid is mandatory to prevent fatal granulomatous amebic encephalitis. In the case presented here amebic trophozoites were detected in a routine cerebrospinal fluid sample. The antibiotic treatment and the apparently low virulence of this isolate were responsible for the benign progression of the infection.

Microbiology (medical)Pathologymedicine.medical_specialtymedicine.drug_classCerebrospinal fluid sampleMolecular Sequence DataAntibioticsVirulenceAcanthamoebaCase ReportsLoboseaCerebrospinal fluidRNA Ribosomal 18SmedicineAnimalsHumansAmebicidesCerebrospinal FluidbiologyAcanthamoeba infectionAmebiasisDNA ProtozoanMiddle Agedmedicine.diseasebiology.organism_classificationAcanthamoebaEncephalitisFemaleRNA ProtozoanEncephalitisJournal of Clinical Microbiology
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