Search results for "Amination"
showing 10 items of 1702 documents
Media-fill simulation tests in manual and robotic aseptic preparation of injection solutions in syringes
2014
Objective The purpose of this study was to evaluate the contamination rate of media-fill products either prepared automated with a robotic system (APOTECAchemo™) or prepared manually at cytotoxic workbenches in the same cleanroom environment and by experienced operators. Media fills were completed by microbiological environmental control in the critical zones and used to validate the cleaning and disinfection procedures of the robotic system. Methods The aseptic preparation of patient individual ready-to-use injection solutions was simulated by using double concentrated tryptic soy broth as growth medium, water for injection and plastic syringes as primary packaging materials. Media fills w…
Does the Artery-first Approach Improve the Rate of R0 Resection in Pancreatoduodenectomy? A Multicenter, Randomized, Controlled Trial
2019
[Objective]: To compare the rates of R0 resection in pancreatoduodenectomy (PD) for pancreatic and periampullary malignant tumors by means of standard (ST-PD) versus artery-first approach (AFA-PD). [Background]: Standardized histological examination of PD specimens has shown that most pancreatic resections thought to be R0 resections are R1. “Artery-first approach” is a surgical technique characterized by meticulous dissection of arterial planes and clearing of retropancreatic tissue in an attempt to achieve a higher rate of R0. To date, studies comparing AFA-PD versus ST-PD are retrospective cohort or case-control studies. [Methods]: A multicenter, randomized, controlled trial was conducte…
Coronary CT angiography: a guide to examination, interpretation, and clinical indications
2021
Introduction: The introduction of Cardiac Computed Tomography (CCT) has changed the paradigm in the field of diagnostic cardiovascular medicine. CCT is the primary tool in the assessment of suspected Coronary Artery Disease (CAD) and should be followed by functional assessment when needed to stratify disease and to plan potential interventional or surgical therapy. Areas Covered: We provided the current state of the knowledge on the main aspects of technique of examination, image interpretation and clinical indications. We have focused our attention on the basic routine applications and activities. Expert Opinion: The primary role of CCT in suspected CAD will progressively become the standa…
Sonography and computed tomography in the diagnosis of orbitocranial malformations and tumors
1987
Standardized sonography and CT scanning have distinct advantages and disadvantages in the evaluation of patients with orbital diseases. Echography provides an efficient screening examination in patients presenting with signs and symptoms of orbital pathology. It allows the detection, localization, measurement and in almost 80% differentiation of orbital lesions. High resolution CT scanning gives an excellent topographic display of masses in the orbit. In visualization of intracranial causes of orbital processes and demonstration of changes in the posterior third of the orbit, in the orbital bones and the periorbital sinuses it is superior to ultrasonography.
Clinical and genetic update of corneal dystrophies.
2019
The International Committee for Classification of Corneal Dystrophies (IC3D) distinguishes between 22 distinct forms of corneal dystrophy which are predominantly autosomal dominant, although autosomal recessive and X-chromosomal dominant patterns do exist. Before any genetic examination, there should be documentation of a detailed corneal exam of as many affected and unaffected family members as possible, because detailed phenotypic description is essential for accurate diagnosis. Corneal documentation should be performed in direct and indirect illumination at the slit lamp with the pharmacologically dilated pupil. For the majority of the corneal dystrophies, a phenotype-genotype correlatio…
Bleb grading by photographs versus bleb grading by slit‐lamp examination
2019
Purpose Using a bleb-grading system clinically facilitates long-term follow-up of patients with previous glaucoma surgery. Clinical evaluation of these patients can be challenging for untrained ophthalmologists. Morphological bleb configuration might influence planning of follow-up visits in glaucoma patients due to different and individual prognosis after trabeculectomy. In this study, we compared the MaBAGS (Mainz Bleb Appearance Grading System), a classification system for filtering blebs with other classification systems (MBGS/Moorfields Bleb Grading System, IBAGS/Indiana Bleb Appearance Grading Scale) in reference to usability and reliability and compare it to grading by bleb photograp…
Artiflex Toric Phakic Intraocular Lens Implantation in Congenital Nystagmus
2011
Case: A 44-year-old woman with congenital nystagmus and myopic astigmatism in both eyes who was submitted to phakic intraocular lens (pIOL) implantation. Methods: Full ophthalmologic examination including refractive status, corrected (CDVA) and uncorrected (UCVA) monocular and binocular visual acuities, ocular motility, slit-lamp evaluation, tonometry and fundoscopy before and after implantation of toric pIOLs (Artiflex; Ophtec BV, The Netherlands) in both eyes. Results: Preoperative logMAR CDVA were 0.699 and 0.420 in the right and left eye, respectively. Three months after surgery, logMAR UCVA were 0.398 and 0.182, reaching binocular logMAR UCVA of 0.132. There were no changes in nystagmu…
The so-called one-and-a-half syndrome, type II: a new syndrome?
1999
Objective: The term one-and-a-half syndrome, type II, was recently coined and has been applied to two somewhat different eye movement disorders: the loss of voluntary horizontal eye movements except for adduction in one eye (one patient with two lesions, one in the cerebral hemisphere and the other in the cavernous sinus) and the loss of all voluntary horizontal eye movements with adduction nystagmus in the right eye on attempted gaze to the left and preserved abduction in both eyes with the doll’s head maneuver (one patient with infarction of the midbrain). The justification of the term ‘one-and-a-half syndrome, type II’ is questioned. Design: Retrospective analysis of 9000 consecutive ele…
Vorbereitung und Technik der operativen Behandlung von 225 Acetabulumfrakturen
1997
Between December 1986 and November 1995, 222 patients with 225 acetabular fractures were treated operatively by three surgeons in the Department of Traumatology and Emergency Surgery of the University Hospitals of the Catholic University of Leuven. Indications for surgery were unstable fracture, displaced fracture through the acetabular dome and fracture with intra-acetabular fracture fragments. There were 37.3% A-fractures, 49.7% B-fractures, and 13% C fractures according to the AO Classification. In 16.4% of fractures there were primary neurological deficits. Patients were treated operatively after an average of 5.0 days. The Kocher-Langenbeck approach was used in 56.9% of cases, the ilio…
Ten-year follow-up of health-related quality of life among persons with multiple sclerosis
2015
nervous stimulation and stretching exercises (ClinicalTrials.gov NCT01664585). Methods:Women aged 18 to 60 having chronic cervicogenic headache with intensity equal or greater than 45mm during the last two months on Visual Analog Scale (VAS) were randomized either to the treatment group “Therapeutic exercise” (THEX group) or to the control group “Transcutaneous Nervous Stimulation” (TNS group). The clinical examination of participants by physiotherapist was conducted at baseline and after intervention. Participants were asked to report each episode of headache including its intensity (VAS) and duration on a daily basis for 6months in the diary. Headache Impact Test-6 scorewas used to assess…