Search results for "Anemia"
showing 10 items of 352 documents
Management of HCV-Related Liver Disease in Hemophilia and Thalassemia
2018
AbstractChronic infection with the hepatitis C virus (HCV) has long been the dominant complication of substitution therapy in patients with inherited blood disorders and the cause of anticipated death due to end-stage liver disease. In hemophilia, transmission of HCV with clotting factors concentrates started to be curbed in the mid-1980s following the adoption of procedures of virus inactivation of concentrates based on heat, whereas in the 1990s treatment of HCV infection with interferon monotherapy was attempted, however, with little success. The advent of combination therapy of interferon with ribavirin led to a substantial improvement of treatment outcome (40% rate of cure), that howev…
Anemia is not predictive of sustained virological response in liver transplant recipients with hepatitis C virus who are treated with pegylated inter…
2011
In the immunocompetent setting, antiviral therapy–related anemia has recently been shown to be associated with a sustained virological response (SVR). Our goal was to assess whether this is also true for liver transplantation (LT). We included 160 LT patients with recurrent hepatitis C virus (HCV) who were treated with pegylated interferon and ribavirin (RBV) between 2002 and 2010; 76% of the patients were men, the median age of the patients was 56 years (range = 33-75 years), 63% had advanced fibrosis, and 86% were infected with HCV genotype 1a or 1b. The baseline immunosuppression was tacrolimus in 56% of the patients. Mycophenolate mofetil (MMF) was used in 15%. Anemia was defined as a h…
From the oxygen to the organ protection: Erythropoietin as protagonist in internal medicine
2006
Erythropoietin (EPO), already known as the stimulating hormone for erythropoiesis, has shown different and interesting pleiotropic actions. It does not only affect erythroid cells, but also myeloid cells, lymphocytes and megakaryocytes. This hormone can also enhance phagocytic function of the polymorphonuclear cells and reduce the activation of macrophages, thus modulating the inflammatory process.Moreover, hematopoietic and endothelial cells probably have the same cellular origin, and the discovery of erythropoietin receptors (EPO-R) also on mesangial and myocardial cells, smooth muscle fibrocells and neurons has prompted the study of the non-erythropoietic functions of this hormone.The in…
Iron intake among Lebanese women: sociodemographic factors, iron-rich dietary patterns, and preparation of hummus, a Mediterranean dish
2021
Background: Plant-based foods such as hummus are alternative to animal protein, and when properly pre-pared, they help to alleviate nutritional iron deficiency that leads to anemia, a global health problem. Objective: The objective was to assess iron intake among Lebanese women and related participant’s charac-teristics, discern iron-rich dietary patterns, evaluate their association with nutrients intake and participant’s sociodemographic characteristics, and identify the women preparing hummus traditionally and properly for an enhanced iron bioavailability. Design: A cross-sectional study of 400 Lebanese women (18–74 years old) was conducted in Lebanon. Data from a questionnaire, including…
Impatto dell'anemia sulla prognosi dei pazienti sottoposti a PCI
2011
Management of anemia: blood loss in orthopaedic surgery
2010
Major ortopaedic surgery and high energy trauma are often responsible of acute bleeding. Long bones and pelvis fractures are correlated with increased blood loss. The final consequence of a major bleeding is hypovolemic shock. The reduced oxygen tension of tissue could be responsible of heart attack, arrythmia, ictus, multi organ deficiency. For these reasons, it is important to immediately recognize and correct all potential bleeding in order to avoid complications. In orthopaedics the elective treatments in the managenment of hypovolemia are different. Blood banks and allogenic blood components have had an important impact on operative treatment and health care worldwide. erythropoietin h…
UNA PANORAMICA SULL’ANEMIA SIDEROPENICA NEGLI ATLETI/AN OVERVIEW ON IRON DEFICIENCY ANEMIA IN ATHLETES
2012
Diversi studi in letteratura riportano come la capacità prestativa degli atleti di endurance sia fortemente compromessa in seguito all’insorgenza di anemia sideropenica. Questa, infatti, è una delle più importanti cause di overtraining negli atleti che pratica attività sportive di lunga durata come: la maratona, la marcia, il ciclismo. Tra le diverse cause di anemia ferropriva ricordiamo: una dieta inadeguata a soddisfare le richieste di ferro dell’organismo, una riduzione dell’assorbimento di ferro a livello intestinale e/o un’eccessiva perdita di questo elemento da parte dell’atleta. Il controllo periodico tramite analisi ematochimiche, metaboliche e funzionali potrebbe essere un valido s…
Anemia management in end stage renal disease patients undergoing dialysis: a comprehensive approach through machine learning techniques and mathemati…
2016
Kidney impairment has global consequences in the organism homeostasis and a disorder like Chronic Kidney Disease (CKD) might eventually exacerbates into End Stage Renal Disease (ESRD) where a complete renal replacement therapy like dialysis is necessary. Dialysis partially reintegrates the blood ltration process; however, even when it is associated to a pharmacological therapy, this is not su fficient to completely replace the renal endocrine role and causes the development of common complications, like CKD secondary anemia (CKD-anemia) The availability of exogenous Erythropoiesis Stimulating Agents (ESA, synthetic molecules with similar structure and same mechanism of action as human eryth…
Autoimmune gastritis among T1D individuals – important association?
2015
Częstość zachorowań na cukrzycę typu 1 (T1D) wciąż wzrasta. Pacjenci z T1D należą do grupy zwiększonego ryzyka rozwoju innych chorób autoimmunologicznych ze względu na podobne patogenetyczne podłoże zaburzeń. Wraz z czasem trwania choroby pacjenci narażeni są na występowanie powikłań. Jednym z nierzadko występujących objawów jest anemia. Kiedy wykluczy się podstawowe przyczyny występowania anemii, w diagnostyce różnicowej należy wziąć pod uwagę prawdopodobieństwo obecności towarzyszącej choroby z autoagresji – autoimmunologicznego zanikowego zapalenia żołądka. Do jej objawów zalicza się nie tylko anemia makrocytarna, spowodowana niedoborem witaminy B12, ale także mikrocytarna – z niedoboru …