Search results for "Ang"

showing 10 items of 39486 documents

MTOR inhibitor-based combination therapies for pancreatic cancer

2018

Background: Although the mechanistic target of rapamycin (MTOR) kinase, included in the mTORC1 and mTORC2 signalling hubs, has been demonstrated to be active in a significant fraction of patients with pancreatic ductal adenocarcinoma (PDAC), the value of the kinase as a therapeutic target needs further clarification. Methods: We used Mtor floxed mice to analyse the function of the kinase in context of the pancreas at the genetic level. Using a dual-recombinase system, which is based on the flippase-FRT (Flp-FRT) and Cre-loxP recombination technologies, we generated a novel cellular model, allowing the genetic analysis of MTOR functions in tumour maintenance. Cross-species validation and pha…

therapeutic resistance0301 basic medicineCancer ResearchCell SurvivalMAP Kinase Signaling Systempancreatic cancerAntineoplastic AgentsContext (language use)Mechanistic Target of Rapamycin Complex 2mTORC1Mechanistic Target of Rapamycin Complex 1BiologymTORC2BortezomibMice03 medical and health sciencesCell Line TumorPancreatic cancermedicineAnimalsHumansExtracellular Signal-Regulated MAP KinasesMechanistic target of rapamycinPI3K/AKT/mTOR pathwayBenzoxazolesKinaseMTORTOR Serine-Threonine Kinasesmedicine.diseaseddc:3. Good healthPancreatic NeoplasmsPyrimidines030104 developmental biologyOncologybiology.proteinCancer researchCamptothecinTOR Serine-Threonine KinasesPhosphatidylinositol 3-KinaseTranslational TherapeuticsProto-Oncogene Proteins c-aktBiologieCarcinoma Pancreatic Ductal
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An Autonomous System to Take Angular Thermal-Infrared Measurements for Validating Satellite Products

2015

An autonomous system for field land surface temperature (LST) measurements taken at different observation angles was developed to be deployed easily at any conventional meteorological tower station. The system permits ground-truth data to be acquired on a continuous basis, and angularly scans land and sky hemispheres with a single thermal-infrared (TIR) radiometer. This paper describes the autonomous angular system and the methodology to assess ground-truth LST and relative-to-nadir emissivity data from system measurements. Ground-truth LSTs were used to validate satellite-retrieved LST products at two experimental sites (rice crop and shrubland areas). The relative-to-nadir emissivity valu…

thermal-infrared; land surface temperature; angular system; emissivity; satellite product Validation; emissivity anisotropyThermal infraredRadiometerMeteorologyLand surface temperaturesatellite product Validationmedia_common.quotation_subjectthermal-infraredScienceQland surface temperatureangular systemSkyemissivityEmissivityGeneral Earth and Planetary SciencesEnvironmental scienceemissivity anisotropySatelliteAutonomous system (mathematics)Anisotropymedia_commonRemote sensingRemote Sensing
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Quasiparticle properties of nonequilibrium gluon plasma

2018

We apply classical gluodynamics to early stages of ultrarelativistic heavy-ion collisions. We start by giving a brief overview of QCD. Then we proceed to the space-time evolution of ultrarelativistic heavy-ion collisions in the color glass condensate framework and go through the basics of real-time gluodynamics on the lattice in the temporal gauge. We study the plasmon mass scale in three- and two-dimensional systems by comparing three different methods to measure the mass scale. The methods are a formula which can be derived from Hard Thermal Loop effective theory at leading order (HTL), the effective dispersion relation (DR) and measurement of the plasma oscillation frequency triggered by th…

thermalizationnonequilibriumkvarkki-gluoniplasmalattice field theoryquasiparticleplasmon masshiukkasfysiikkahigh energy physicsclassical Yang-Mills theoryplasmonitplasmonquantum chromodynamicsnuclear theorylattice gauge theorykvanttiväridynamiikkakvanttikenttäteoriaclassical field theory
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High Frequency Data Acquisition System for Modelling the Impact of Visitors on the Thermo-Hygrometric Conditions of Archaeological Sites: A Casa di D…

2018

[EN] The characterization of the microclimatic conditions is fundamental for the preventive conservation of archaeological sites. In this context, the identification of the factors that influence the thermo-hygrometric equilibrium is key to determine the causes of cultural heritage deterioration. In this work, a characterization of the thermo-hygrometric conditions of Casa di Diana (Ostia Antica, Italy) is carried out analyzing the data of temperature and relative humidity recorded by a system of sensors with high monitoring frequency. Sensors are installed in parallel, calibrated and synchronized with a microcontroller. A data set of 793,620 data, arranged in a matrix with 66,135 rows and …

thermo-hygrometric balanceFrequency dataContext (language use)010501 environmental scienceslcsh:Chemical technologyLogistic regressionrelative humidity01 natural sciencesBiochemistryArticleAnalytical ChemistryThermo-hygrometric balanceContinuous monitoringVisitorsvisitors; temperature; relative humidity; thermo-hygrometric balance; continuous monitoring; preventive conservationlcsh:TP1-1185Relative humidityElectrical and Electronic EngineeringInstrumentation0105 earth and related environmental sciencesEnvironmental humidity010401 analytical chemistryContinuous monitoringTemperatureClimatic variablestemperatureRelative humiditypreventive conservationvisitorsArchaeologyAtomic and Molecular Physics and Opticscontinuous monitoring0104 chemical sciencesFISICA APLICADAEnvironmental scienceThermal balancePreventive conservation
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Thermal and thermo-oxidative stability and kinetics of decomposition of PHBV/sisal composites

2017

The decomposition behaviours of composites made of poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) and sisal were assessed in terms of thermal stability and decomposition kinetics, under inert and oxidative conditions, by means of multi-rate linear non-isothermal thermogravimetric experiments. A statistical design of experiments was applied to study the influence of the addition of sisal (0-10-20-30%wt), the presence coupling agent (Yes/No) and the applied conditions of work (inert or oxidative). An improvement of the thermal and thermo-oxidative stability of PHBV with the addition of sisal was observed for all cases. An accurate methodology based on iso-conversional methods was applied…

thermo-oxidative decompositionMaterials scienceGeneral Chemical EngineeringKinetics02 engineering and technology010402 general chemistry01 natural sciencesnatural fibresThermalwaste-to-fuelChemical Engineering (all)Thermal stabilityComposite materialthermal decompositionSISALcomputer.programming_languageInertBiocompositesMaterials compostosTermoplàsticsChemistry (all)Thermal decompositionpoly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV)General Chemistrysisal021001 nanoscience & nanotechnologyBiocomposites; kinetics; natural fibres; poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV); sisal; thermal decomposition; thermo-oxidative decomposition; waste-to-fuel; Chemistry (all); Chemical Engineering (all)Decomposition0104 chemical scienceskinetics0210 nano-technologycomputerChemical Engineering Communications
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Thermoluminescence response of sodalime glass irradiated with photon and electron beams in the 1-20 Gy range

2011

Abstract The thermoluminescence response of a watch commercial glass was studied after irradiation with photons and electrons, in the range 1–20 Gy, of interest in accidental dosimetry; a linear response was obtained with both beams. This result, together with the satisfactory time stability of the thermoluminescence signal, indicates this glass as a potential material for retrospective dosimetry applications.

thermoluminecence watch glass photons electronsRange (particle radiation)RadiationPhotonMaterials sciencebusiness.industryRadiochemistryElectronThermoluminescenceOpticsDosimetryIrradiationbusinessInstrumentation
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Applications and non-idealities of submicron Al–AlOx–Nb tunnel junctions

2016

We have developed a technique to fabricate sub-micron, 0.6µm×0.6µm Al-AlOx-Nb tunnel junctions using a standard e-beam resist, angle evaporation and double oxidation of the tunneling barrier, resulting in high quality niobium, as determined by the the high measured values of the critical temperature TC ∼ 7.5 K and the gap ∆ ∼ 1.3 meV. The devices show great promise for local nanoscale thermometry in the temperature range 1 - 7.5 K. Electrical characterization of the junctions was performed at sub-Kelvin temperatures both with and without an external magnetic field, which was used to suppress superconductivity in Al and thus bring the junction into a normal-metal-insulator-superconductor (NI…

thermometryNiobiumFOS: Physical scienceschemistry.chemical_element02 engineering and technology01 natural sciencesMesoscale and Nanoscale Physics (cond-mat.mes-hall)0103 physical sciencesMaterials ChemistryElectrical and Electronic Engineering010306 general physicsNIS junctionQuantum tunnellingSuperconductivityPhysicssuperconducting tunnel junctionCondensed Matter - Mesoscale and Nanoscale Physicssub-gap currentbusiness.industryMetals and AlloysAtmospheric temperature range021001 nanoscience & nanotechnologyCondensed Matter PhysicsEvaporation (deposition)Magnetic fieldCharacterization (materials science)ResistchemistryCeramics and CompositesOptoelectronicsniobium0210 nano-technologybusinessSuperconductor Science and Technology
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Interactive Tools for the Preservation, Dissemination and Study of Silk Heritage—An Introduction to the SILKNOW Project

2018

Silk was a major factor for progress in Europe, mostly along the Western Silk Road’s network of production and market centers. The silk trade also allowed for the exchange of ideas and innovations, having impacts at economic, technical, functional, cultural and symbolic levels. However, silk has today become a seriously endangered heritage. Although many European specialized museums are devoted to its preservation, they usually lack the size and resources to take advantage of state-of-the-art digital technologies. The aim of this paper is twofold; firstly, we introduce SILKNOW, an interdisciplinary project that has been recently funded by the H2020 Programme of the European Union in order t…

thesaurusArchitectural engineeringComputer Networks and CommunicationsNeuroscience (miscellaneous)silk heritage02 engineering and technologyinteractive toolslcsh:Technology01 natural sciencesOrder (exchange)0202 electrical engineering electronic engineering information engineeringmedia_common.cataloged_instanceEuropean unionlcsh:SciencePatrimoni culturalmedia_commonlcsh:T010401 analytical chemistry020207 software engineering0104 chemical sciencesComputer Science ApplicationsHuman-Computer InteractionSILKvirtuallcsh:QBusinessMultimodal Technologies and Interaction
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The (im)possible success of disadvantaged students. Reflections on education, migration and social change

2019

The paper focuses on the ?unexpected pathways? of successful students with an immigrant background: these biographical routes, that seems socially impossible, raise theoretical issues around the individual-society, actor-structure relationship. Disadvantaged students who succeed represent a sociological challenge in the attempt to understand atypical situations and to identify the institutional processes and the structural opportunities that facilitate them, reducing ethnic inequalities in education. This framework is the starting point of the Su.Per. project (Success in educational pathways of students with immigrant background), based on the collection of written autobiographies of 65 imm…

these biographical routes [Mariagrazia The paper focuses on the ?unexpected pathways? of successful students with an immigrant background]relación educación-migración-sociedadmigration and social change Santagatithat seems socially impossibleattending upper secondary education in Northern Italy. The biographical approach allows to deepen the social change that derives from the positive impact of immigration on education. Within this interpretative perspectiveéxito escolar 51 57raise theoretical issues around the individual-societyactor-structure relationship. Disadvantaged students who succeed represent a sociological challenge in the attempt to understand atypical situations and to identify the institutional processes and the structural opportunities that facilitate thembut also giving voice and supports to disadvantaged studentsschool successSettore SPS/08 - SOCIOLOGIA DEI PROCESSI CULTURALI E COMUNICATIVIthat considers possible the educational success of immigrant studentsimmigrant students:SOCIOLOGÍA [UNESCO]students of immigrant originreducing ethnic inequalities in education. This framework is the starting point of the Su.Per. project (Success in educational pathways of students with immigrant background)the article underlines the contribute of the Su.Per. project to a new ?definition of the situation?and introducing them to a field of unforeseen possibilities. education-migration-society relationship1137-7038 8537 Arxius de sociologia 525290 2019 40 7038139 The (im)possible success of disadvantaged students. Reflections on educationdrawing new narratives and discourses on inequalitieseducational successUNESCO::SOCIOLOGÍAMariagrazia The paper focuses on the ?unexpected pathways? of successful students with an immigrant background: these biographical routesbased on the collection of written autobiographies of 65 immigrant studentsalumnos de origen inmigrante
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Taxa a rischio nella flora vascolare della Sicilia

2011

Biogeographia vol. XgO( - 2011 (Pubblicato il 23 dicembre 2011) La Biogeografia de/Ia Sicilia Taxa a rischio nella flora vascolare della Sicilia FRANCESCO MARIA RAIMONDO, GIUSEPPE BAZAN, ANGELO TROIA Dzjzartimento di Biologia Ambientale e Biodiversitd, Universird di Palermo via Arc/aimfi 38, 90123 Palermo (Italy) Key words: threatened species, vascular flora, red list, Sicily. SUMMARY An analysis was made to update the regional red list of endangered vascular plants in Sicily which, with 3,252 taxa (including a noteworthy number of endemic species), is one of the richest areas in the Mediterranean region. Considering previous regional and national red lists, recent taxonomic and floristic lite…

threatened species vascular flora red list Sicily Italy IUCN conservazione tutela flora a rischio specie estinteGlobal and Planetary ChangeEcologySettore BIO/02 - Botanica SistematicaSettore BIO/03 - Botanica Ambientale E ApplicataLife SciencesEcology Evolution Behavior and SystematicsBiogeographia – The Journal of Integrative Biogeography
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