Search results for "Angiofibroma"
showing 3 items of 3 documents
Juvenile nasopharyngeal angiofibroma with orbital extension
2015
Abstract Clinical case The case of a 21-year-old male with a history of left proptosis and diplopia of two weeks of onset is presented. The MRI showed an ethmoid-orbital vascular lesion with anterior skull base invasion and orbital extension. Biopsy of the ethmoid confirmed fibrovascular tissue, which supported the diagnosis of angiofibroma. Discussion It is a benign neoplasm with local characteristics of malignancy due to its ability to invade adjacent areas. In this case, the debut presented with manifestations of orbital extension. A broad and multidisciplinary approach is needed in order to improve prognosis.
Angiofibroma nasofaríngeo juvenil con extensión orbitaria
2015
Resumen Caso clinico Varon de 21 anos con historia de exoftalmos izquierdo y diplopia de 2 semanas de evolucion. La resonancia magnetica mostro una lesion muy vascularizada etmoido-orbitaria con invasion de base del craneo anterior y extension orbitaria. La biopsia etmoidal confirmo un tejido fibrovascular compatible con angiofibroma. Discusion El angiofibroma nasofaringeo juvenil (ANJ) es un tumor benigno con caracteristicas locales de malignidad debido a su capacidad de invadir areas adyacentes. En nuestro caso, el comienzo se presenta con manifestaciones de extension orbitaria. Consideramos necesario un conocimiento amplio y un abordaje multidisciplinario con el fin de mejorar el pronost…
Frequent chromosomal gains in recurrent juvenile nasopharyngeal angiofibroma.
2007
Juvenile nasopharyngeal angiofibroma (JNA) is a rare benign tumor, mostly affecting adolescent males. Some patients develop recurrences after surgery independently of completeness of removal. Only very limited data concerning underlying chromosomal changes are available. We therefore analyzed samples of 22 JNAs, including six recurrences, with comparative genomic hybridization (CGH). Additionally, quantitative image cytometry was used for measurement of DNA aneuploidy in representative samples. Of the 13 primary JNAs without later recurrence, DNA gains were identified on autosomes in only two samples. Four patients with one or two recurrences were included in the study; for one of these, no…