Search results for "Antrodia"

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Lanostanoids from fungi: a group of potential anticancer compounds.

2012

Lanostanes are a group of tetracyclic triterpenoids derived from lanosterol. They have relevant biological and pharmacological properties, such as their cytotoxic effects via induction of apoptosis. This review compiles the most relevant lanostanoids studied from 2000 to 2011, principally those isolated from Ganoderma lucidum and other related fungi, such as Poria cocos, Laetiporus sulphureus, Inonotus obliquus, Antrodia camphorata, Daedalea dickinsii, and Elfvingia applanata, which have great potential as anticancer agents because of their cytotoxic or apoptotic effects. The compounds were selected on the basis of their proapoptotic mechanisms, through their ability to modify transcription…

Cell cycle checkpointStereochemistryPharmaceutical ScienceAntineoplastic AgentsAnalytical Chemistrychemistry.chemical_compoundLanosterolDrug DiscoveryMedicinal fungiAntrodiaLaetiporus sulphureusCytotoxicityPharmacologybiologyMolecular StructureLanosterolOrganic ChemistryGanodermaCell Cycle CheckpointsCell cyclebiology.organism_classificationComplementary and alternative medicinechemistryBiochemistryMolecular MedicineInonotus obliquusJournal of natural products
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