Search results for "Anus"

showing 10 items of 841 documents

On the complexity of the Saccharomyces bayanus taxon: Hybridization and potential hybrid speciation

2014

Although the genus Saccharomyces has been thoroughly studied, some species in the genus has not yet been accurately resolved; an example is S. bayanus, a taxon that includes genetically diverse lineages of pure and hybrid strains. This diversity makes the assignation and classification of strains belonging to this species unclear and controversial. They have been subdivided by some authors into two varieties (bayanus and uvarum), which have been raised to the species level by others. In this work, we evaluate the complexity of 46 different strains included in the S. bayanus taxon by means of PCR-RFLP analysis and by sequencing of 34 gene regions and one mitochondrial gene. Using the sequenc…

Evolutionary GeneticsSaccharomyces bayanusDIVERSITYSequence Homologylcsh:MedicineSaccharomycesPolymerase Chain Reaction//purl.org/becyt/ford/1 [https]Genética y HerenciaPCR-RFLP analysisFungal EvolutionCluster Analysislcsh:ScienceGenome EvolutionPhylogenyGeneticsMultidisciplinarySACCHAROMYCES EUBAYANUSPhylogenetic analysisbiologyStrain (biology)Systems BiologyGenomicsS. bayanusPolymorphism Restriction Fragment LengthCIENCIAS NATURALES Y EXACTASResearch ArticleEvolutionary ProcessesGenetic SpeciationMolecular Sequence DataIntrogressionMycologyGenome ComplexityMicrobiologyGenètica molecularCiencias BiológicasSaccharomycesSpecies SpecificityPhylogeneticsGenetic variationGeneticsYEAST//purl.org/becyt/ford/1.6 [https]HybridizationAllelesHybridEvolutionary BiologyBase Sequencelcsh:ROrganismsFungiBiology and Life SciencesComputational BiologyGenetic VariationSACCHAROMYCES PASTORIANUSSequence Analysis DNAComparative Genomicsbiology.organism_classificationYeastGenetics PopulationHaplotypesFungal ClassificationHybridization GeneticHybrid speciationlcsh:Q
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Reminiscenze e rielaborazioni avianee in due carmi di Bellino Bissolo (Spec. vite I 5; I 9)

2020

L'intervento è dedicato alla figura e all'opera di Bellino Bissolo, poeta milanese del Duecento, autore di tre testi didattico-moralistici in latino e in distici elegiaci, il «Liber legum moralium», il «De regimine vite et sanitatis» e, soprattutto, lo «Speculum vite». Nella prima parte del testo viene tracciato lo "status quaestionis" relativo all'autore, all'opera e agli studi su di essa. La seconda e più ampia parte è invece fondata sulla lettura e l'analisi di due brevi componimenti dello «Speculum vite» (I 5; I 9), di carattere e impianto narrativo-favolistico, per entrambi i quali si ipotizza una fruizione, da parte del Bissolo, delle favole di Aviano, che tanto successo hanno avuto n…

FableBellino BissoloSettore L-FIL-LET/08 - Letteratura Latina Medievale E UmanisticaMoralistic-didactic PoetryAvianoFavolaAvianusPoesia moralistico-didascalica
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Libre de animals de casar

Ms Títol obtingut de l'enquadernació original, allí mateix un altre títol: "Libre de animals de casar" Col·lació: Paper, i + 4-96 f. (foliació original en nombres aràbics del f. 4-91 i del f. 92 al 96 numeració actual) ; caixa d'escriptura 230 x 160 mm Composició: Escrit a línia tirada a 35 línies (f. 48r ) per tres copistes Escriptura: Humanística cursiva Decoració: Al mig del text hom troba alguns dibuixos a tall d'iI·lustració (f. 37r, 40r, 47v, 68r, 83r i 84v) Enquadernació: Pergamí, enfosquit i tacat, restaurat en l'any 2013 Origen: Escrit a finals del segle XV o començaments del segle XVI a l'antiga Corona d'Aragó Signatura anterior: 866 Signatura actual: València, Universitat de Valè…

Falconeria Manuscrits
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Variation in contents of main active components and antioxidant activity in leaves of different pigeon pea cultivars during growth.

2013

Pigeon pea is an important and multiuse grain legume crop, and its leaves are a very valuable natural resource. To obtain a high-quality biological resource, it is necessary to choose the excellent cultivar and determine the appropriate harvest time. In this study, the variation in contents of main active components and antioxidant activity in leaves of six pigeon pea cultivars during growth were investigated. The level of each individual active component significantly varied during growth, but with a different pattern, and this variation was different among cultivars. Flavonoid glycosides orientin, vitexin, and apigenin-6,8-di-C-α-L-arabinopyranoside showed two peak values at mid-late and …

FlavonoidsAntioxidantPlant ExtractsHarvest timemedicine.medical_treatmentActive componentsData_CODINGANDINFORMATIONTHEORYGeneral ChemistryBiologyAntioxidantsCropPlant LeavesHorticultureCajanusPhenolsBotanymedicineCultivarGlycosidesGeneral Agricultural and Biological SciencesLegumeJournal of agricultural and food chemistry
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New insights on the occurrence and conservation status in Italy of Alessioporus ichnusanus (Boletaceae), an IUCN red listed mycorrhizal species

2020

The conservation status of Alessioporus ichnusanus is discussed considering new insights emerged from the IUCN global assessment. New locations were identified and Italy is confirmed as the center of distribution of this species. According to the IUCN categories and criteria, A. ichnusanus is assigned to the category Vulnerable C2a(i).

Fungal biodiversityfood.ingredienthabitat lossXerocomus ichnusanusPlant ScienceXerocomus ichnusanusFungal biodiversityAlessioporus ichnusanusfoodBoletaceaeIUCN Red Listthreat statuEcology Evolution Behavior and SystematicsXerocomus ichnusanuBoleto Sardo; Fungal biodiversity; fungal conservation; habitat loss; IUCN Red List; threat status; Xerocomus ichnusanusfungal conservationbiologyBoleto SardoEcologySettore BIO/02 - Botanica Sistematicathreat statusbiology.organism_classificationIUCN Red ListGeographyHabitat destructionSettore BIO/03 - Botanica Ambientale E ApplicataConservation statushabitat loFungal biodiversity; Boleto Sardo; Xerocomus ichnusanus; habitat loss; threat status; IUCN Red List; fungal conservation
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Osservazioni sulla pretesa esistenza di una 'legis actio per manus iniectionem' in relazione al 'furtum manifestum'

2006

Si mette in discussione l'idea corrente in storiografia secondo cui in età arcaica si sarebbe potuto agire con 'legis actio per manus iniectionem' nei confronti del fur manifestus pubere e di condizione libera. Sulla base di un riesame critico dei passi su cui questa convinzione tradizionalmente si fonda si segnalano le anomalie che tale pretesa applicazione della legis actio avrebbe avuto rispetto alle altre che sono testimoniate con sicurezza dalle fonti di cui si dispone.

Furtumlegis actio per manus iniectionemSettore IUS/18 - Diritto Romano E Diritti Dell'Antichita'
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Characterization of five fungal endophytes producing Cajaninstilbene acid isolated from pigeon pea [Cajanus cajan (L.) Millsp].

2011

Five fungal endophytes (K4, K5, K6, K9, K14) producing Cajaninstilbene acid (CSA, 3-hydroxy-4-prenyl-5-methoxystilbene-2-carboxylic acid) were isolated from the roots of pigeon pea [Cajanus cajan (L.) Millsp.]. CSA is responsible for the prominent pharmacological activities in pigeon pea. The amount of CSA in culture solution varied among the five fungal endophytes. K4 produced the highest levels of CSA (1037.13 µg/L) among the endophytes tested after incubation for five days. Both morphological characteristics and molecular methods were used for species identification of fungal endophytes. The five endophytic isolates were characterized by analyzing the internal transcribed spacer (ITS) rR…

FusariumApplied Microbiologylcsh:MedicineMycologyPlant ScienceBiologyPlant RootsMicrobiologyCajanusPlant MicrobiologyCajanusFusariumTubulinBotanyFusarium oxysporumStilbenesEndophytesInternal transcribed spacerMedicinal plantslcsh:ScienceBiologyMicrobial MetabolismMultidisciplinarylcsh:RFungal geneticsFungiBotanyfood and beveragesRibosomal RNAbiology.organism_classificationSalicylatesFusariosisFungal ClassificationNeonectrialcsh:QResearch ArticleBiotechnologyPloS one
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Oxidative stress inhibits IFN-α-induced antiviral gene expression by blocking the JAK–STAT pathway

2006

Abstract BACKGROUND/AIMS: Unresponsiveness to IFN-alpha is common in chronic hepatitis C. Since conditions associated with an increased oxidative stress (advanced age, steatosis, fibrosis, iron overload, and alcohol consumption) reduce the likelihood of response, we hypothesized that oxidative stress may affect the antiviral actions of IFN-alpha. METHODS: We examined in a human hepatocellular carcinoma cell line (Huh-7) the effect of hydrogen peroxide (H2O2), as a generator of oxidative stress, on the IFN-alpha signaling pathway. RESULTS: Pretreatment of Huh-7 cells with 0.5-1 mM H2O2 resulted in the suppression of the IFN-alpha-induced antiviral protein MxA and of IRF-9 mRNA expression. Th…

Gene Expression Regulation ViralMyxovirus Resistance ProteinsCarcinoma HepatocellularBlotting WesternAntiviral proteinProtein tyrosine phosphataseInterferon alpha-2Biologymedicine.disease_causechemistry.chemical_compoundGTP-Binding ProteinsCell Line TumormedicineHumansRNA NeoplasmHepatologyTyk-2Reverse Transcriptase Polymerase Chain ReactionSTATLiver NeoplasmsInterferon-alphaJAK-STAT signaling pathwayTyrosine phosphorylationHydrogen PeroxideJanus Kinase 1Flow CytometryInterferon-Stimulated Gene Factor 3 gamma SubunitRecombinant ProteinsIFN-aJAK-1Oxidative StressSTAT Transcription FactorsHydrogen peroxide; IFN-a; STAT; JAK-1; Tyk-2chemistryImmunologySTAT proteinCancer researchSignal transductionTyrosine kinaseOxidative stressSignal TransductionJournal of Hepatology
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Targeting the JAK/STAT Pathway: A Combined Ligand- and Target-Based Approach

2021

Janus kinases (JAKs) are a family of proinflammatory enzymes able to mediate the immune responses and the inflammatory cascade by modulating multiple cytokine expressions as well as various growth factors. In the present study, the inhibition of the JAK-signal transducer and activator of transcription (STAT) signaling pathway is explored as a potential strategy for treating autoimmune and inflammatory disorders. A computationally driven approach aimed at identifying novel JAK inhibitors based on molecular topology, docking, and molecular dynamics simulations was carried out. For the best candidates selected, the inhibitory activity against JAK2 was evaluated in vitro. Two hit compounds with…

General Chemical EngineeringTransducersBioinformatics and computational biology Inhibitors Inhibition Peptides and proteins MoleculesLibrary and Information SciencesLigands01 natural sciencesstatArticleProinflammatory cytokine0103 physical sciencesProtein Kinase InhibitorsJanus KinasesTofacitinib010304 chemical physicsActivator (genetics)ChemistryJAK-STAT signaling pathwayGeneral Chemistry0104 chemical sciencesComputer Science ApplicationsCell biology010404 medicinal & biomolecular chemistryDocking (molecular)Signal transductionJanus kinaseSignal TransductionJournal of Chemical Information and Modeling
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Phylogeny of the genus Kluyveromyces inferred from the mitochondrial cytochrome-c oxidase II gene.

2000

A phylogenetic analysis of 17 species belonging to the genus Kluyveromyces and 12 reference and outgroup species was performed using mitochondrial cytochrome-c oxidase II gene sequences. The genus Kluyveromyces appears as a polyphyletic taxon formed by species included within the following four main groups. The Kluyveromyces phaffii group encompasses the species Kluyveromyces blattae, K. phaffii and Kluyveromyces yarrowii. The Kluyveromyces marxianus group is a monophyletic group consisting of the species Kluyveromyces aestuarii, Kluyveromyces dobzhanskii, Kluyveromyces lactis, K. marxianus and Kluyveromyces wickerhamii. The monophyletic Kluyveromyces thermotolerans group is formed by K. th…

GeneticsKluyveromyces lactisbiologyPhylogenetic treeGenes FungalMolecular Sequence DataSequence Analysis DNAGeneral Medicinebiology.organism_classificationMicrobiologyTorulasporaMitochondriaElectron Transport Complex IVKluyveromycesMonophylyKluyveromyces marxianusPhylogeneticsPolyphylyKluyveromycesPhylogenyEcology Evolution Behavior and SystematicsInternational Journal of Systematic and Evolutionary Microbiology
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