Search results for "Aortic"
showing 10 items of 619 documents
The revised ghent nosology; reclassifying isolated ectopia lentis
2014
Inherited ectopia lentis (EL) is most commonly caused by Marfan syndrome (MFS), a multisystemic disorder caused by mutations in FBN1. Historically the diagnosis for patients with EL who have no systemic features of MFS is isolated EL (IEL). However, the Ghent nosology for MFS was updated in 2010 and made some important alterations. In particular, patients with EL and a FBN1 mutation are now categorically diagnosed with MFS, if their mutation has previously been described with aortic dilation/dissection. This carries significant systemic implications, as many patients previously diagnosed with IEL are now reclassified. We provide a review of all published cases of IEL caused by FBN1 mutation…
CRT-724 Can the Aortic Wall Communicate with Us?
2014
Association between aortic aneurysm wall and risk of rupture or dissection. Aortic specimens were obtained from 73 patients (51 men and 22 women, whose median age 61.7± 10.7 years) undergoing surgical repair of thoracic ascending aneurysm (TAA). Histopathological and immunohistochemical analyses
Patient-specific computational evaluation of stiffness distribution in ascending thoracic aortic aneurysm
2021
Quantifying local aortic stiffness properties in vivo is acknowledged as essential to assess the severity of an ascending thoracic aortic aneurysm (ATAA). Recently, the LESI (local extensional stiffness identification) methodology has been established to quantify non-invasively local stiffness properties of ATAAs using electrocardiographic-gated computed tomography (ECG-gated CT) scans. The aim of the current study was to determine the most sensitive markers of local ATAA stiffness estimation with the hypothesis that direct measures of local ATAA stiffness could better detect the high-risk patients. A cohort of 30 patients (12 BAV and 18 TAV) referred for aortic size evaluation by ECG-gated…
Effect of SGLT-2 inhibition in abdominal aortic aneurysm development. Role of RORa in adipose tissue inflammation associated to obesity
2021
El aneurisma aórtico abdominal (AAA) se define como una dilatación local de la arteria aorta a nivel abdominal cuya consecuencia más grave es su ruptura si no se detiene su crecimiento y progresión. Los rasgos patológicos del AAA incluyen un estado inflamatorio crónico que afecta a la pared vascular de la aorta, una degradación progresiva de la matriz extracelular y un aumento en la neovascularización. Esta enfermedad presenta una elevada tasa de mortalidad y en la actualidad el único tratamiento efectivo que se conoce es la intervención quirúrgica, pero no está indicada en pacientes asintomáticos o que presentan un aneurisma de reducido tamaño. Por ello, es fundamental encontrar nuevas est…
Appropriateness of surgery performed for abdominal aortic aneurysm at tertiary hospitals in Spain
2021
Background: The aim of this study was to analyze the appropriateness of the type of repair (open or endovascular) performed for abdominal aortic aneurysm (AAA) in five university hospitals in Spain, according to evidence-based recommendations. Methods: A multicenter, retrospective cross-sectional study of patients with AAA who underwent elective open surgical repair (OSR) or endovascular aneurysm repair (EVAR). Data were collected on demographic and clinical variables and type of surgical repair. A pair of vascular surgeons from each participating hospital performed a blinded assessment based on GRADE recommendations. The concordance between the two evaluators and the agreement between thei…
Association of Oxidative Stress with Aortic Stiffness in Hypertensive Patients with Chronic Kidney Disease
2011
Several studies have consistently demonstrated that arterial stiffness becomes progressively worse as CKD progresses and a negative correlation of oxidative stress with renal function has been described. There is also sound experimental evidence indicating that oxidative stress is involved in atherogenesis. The contribution of oxidative stress to aortic stiffness is less clear. Aim: To analyse the relationship between plasma levels of 8-ISO-prostaglandin F2alpha (8-ISOPGF2alpha), an index of lipid peroxidation, considered a reliable biomarker of oxidative stress, and aortic stiffness in a group of hypertensive patients with chronic kidney disease. Methods: We enrolled 126 hypertensive patie…
RED BLOOD CELL DISTRIBUTION WIDTH PREDICTS MORBIDITY AND MORTALITY AFTER AORTIC VALVE REPLACEMENT
2014
Objective: Red blood cell distribution width (RDW), is a measurement of the size variation as well as an erythrocyte heterogeneity index (i.e., anysocytosis). used in combination with the mean corpuscular volume for anemia diagnosis. However, it is emerging as an useful predictor biomarker of mortality and morbidity of cardiovascular diseases. However, until now no literature data there are about the RDW role in predicting mortality after aortic valve replacement (AVR). Thus, in this pilot study biological significance of elevated RDW values in early outcome following AVR was evaluated Methods: We enrolled 75 patients (mean age 73.5 ±7.9 years) subjected to AVR and/ or not co temporally to …
Relationship between aortic stifness and renal resistance index in hypertensive patients
2014
La sindrome metabolica negli ipertesi essenziali mai trattati farmacologicamente: effetti sulla stiffness aortica
2005
Wewnątrznaczyniowe dwuetapowe leczenie tętniaków aorty brzusznej z użyciem Heli-FX EndoAnchor System
2019
Wstęp: Wyniki leczenia tętniaków aorty brzusznej mimo wprowadzenia nowych technik wewnątrznaczyniowych nadal nie zawsze są zadowalające. Szczególnie trudną grupą pacjentów są osoby z krótką oraz stożkową szyją. W tej grupie chorych często występuje w okresie pooperacyjnym przeciek typu I. Jedną z metod mających temu powikłaniu zapobiec jest zastosowanie wkrętów wewnątrznaczyniowych Heli-FX. Ma to zwiększyć przyleganie systemu stentgraftu do ściany aorty brzusznej oraz zapobiec jego ewentualnej migracji. Materiał i metody: Autorzy niniejszego artykułu proponują zastosowanie leczenia dwuetapowego. Pierwszy etap stanowiła implantacja przedłużki aortalnej tuż poniżej odejścia tętnic nerkowych i…