Search results for "Apparatu"
showing 5 items of 195 documents
The influence of stomatognatic apparatus in atletic performance: the effects of the palatal exteroceptors stimulation in football players
2014
Advances in Nanoliposomes Production for Ferrous Sulfate Delivery
2020
In this study, a continuous bench scale apparatus based on microfluidic fluid dynamic principles was used in the production of ferrous sulfate-nanoliposomes for pharmaceutical/nutraceutical applications, optimizing their formulation with respect to the products already present on the market. After an evaluation of its fluid dynamic nature, the simil-microfluidic (SMF) apparatus was first used to study the effects of the adopted process parameters on vesicles dimensional features by using ultrasonic energy to enhance liposomes homogenization. Subsequently, iron-nanoliposomes were produced at different weight ratios of ferrous sulfate to the total formulation components (0.06, 0.035, 0.02, an…
The ARF GAPs ELMOD1 and ELMOD3 act at the Golgi and Cilia to Regulate Ciliogenesis and Ciliary Protein Traffic
2021
ABSTRACTELMODs are a family of three mammalian paralogs that display GTPase activating protein (GAP) activity towards a uniquely broad array of ADP-ribosylation factor (ARF) family GTPases that includes ARF-like (ARL) proteins. ELMODs are ubiquitously expressed in mammalian tissues, highly conserved across eukaryotes, and ancient in origin, being present in the last eukaryotic common ancestor. We described functions of ELMOD2 in immortalized mouse embryonic fibroblasts (MEFs) in the regulation of cell division, microtubules, ciliogenesis, and mitochondrial fusion. Here, using similar strategies with the paralogs ELMOD1 and ELMOD3, we identify novel functions and locations of these cell regu…
Hyvä valmentaja 10-15-vuotiaiden telinevoimistelussa kilpailevien tyttöjen silmin
2014
Tämän tutkielman tarkoituksena oli kartoittaa hyvän valmentajan ominaisuuksia ja suomalaisten telinevoimistelijatyttöjen tyytyväisyyttä valmentajiinsa. Lisäksi halusin selvittää, täyttivätkö voimistelijatyttöjen omat valmentajat heidän odotuksensa hyvästä, niin sanotusta unelmavalmentajasta. Tutkielman aineistonkeruu suoritettiin helmi-maaliskuussa 2013 sähköisellä kyselylomakkeella, johon saivat vastata aktiivisesti telinevoimistelua harrastavat, 10–15 -vuotiaat tytöt. Tutkimukseen osallistui yhteensä 38 tyttöä 14 eri seurasta. He olivat aktiivisesti kilpailleet viimeisen kahden vuoden aikana eli osallistuneet vähintään yksiin virallisiin, kansallisen tason naistelinevoimistelukilpailuihin…
Lipid Binding Controls Dimerization of the Coat Protein p24 Transmembrane Helix
2019
Abstract Coat protein (COP) I and COP II complexes are involved in the transport of proteins between the endoplasmic reticulum and the Golgi apparatus in eukaryotic cells. The formation of COP I/II complexes at membrane surfaces is an early step in vesicle formation and is mastered by p24, a type I transmembrane protein. Oligomerization of p24 monomers was suggested to be mediated and/or stabilized via interactions within the transmembrane domain, and the p24 transmembrane helix appears to selectively bind a single sphingomyelin C18:0 molecule. Furthermore, a potential cholesterol-binding sequence has also been predicted in the p24 transmembrane domain. Thus, sphingomyelin and/or cholestero…