Search results for "Applications"
showing 10 items of 4965 documents
A visualization technique for accessing solution pool in interactive methods of multiobjective optimization
2015
<pre>Interactive methods of <span>multiobjective</span> optimization repetitively derive <span>Pareto</span> optimal solutions based on decision maker's preference information and present the obtained solutions for his/her consideration. Some interactive methods save the obtained solutions into a solution pool and, at each iteration, allow the decision maker considering any of solutions obtained earlier. This feature contributes to the flexibility of exploring the <span>Pareto</span> optimal set and learning about the optimization problem. However, in the case of many objective functions, the accumulation of derived solutions makes accessing the sol…
Application of Molecular Topology for the Prediction of Reaction Yields and Anti-Inflammatory Activity of Heterocyclic Amidine Derivatives
2011
Topological-mathematical models based on multiple linear regression analyses have been built to predict the reaction yields and the anti-inflammatory activity of a set of heterocylic amidine derivatives, synthesized under environmental friendly conditions, using microwave irradiation. Two models with three variables each were selected. The models were validated by cross-validation and randomization tests. The final outcome demonstrates a good agreement between the predicted and experimental results, confirming the robustness of the method. These models also enabled the screening of virtual libraries for new amidine derivatives predicted to show higher values of reaction yields and anti-infl…
Tolerance, Adaptation, and Cell Response Elicited by Micromonospora sp. Facing Tellurite Toxicity: A Biological and Physical-Chemical Characterization
2022
The intense use of tellurium (Te) in industrial applications, along with the improper disposal of Te-derivatives, is causing their accumulation in the environment, where oxyanion tellurite (TeO32−) is the most soluble, bioavailable, and toxic Te-species. On the other hand, tellurium is a rare metalloid element whose natural supply will end shortly with possible economic and technological effects. Thus, Te-containing waste represents the source from which Te should be recycled and recovered. Among the explored strategies, the microbial TeO32− biotransformation into less toxic Te-species is the most appropriate concerning the circular economy. Actinomycetes are ideal candidates in…
Influence of the Screw Positioning on the Stability of Locking Plate for Proximal Tibial Fractures: A Numerical Approach
2020
Tibial fractures are common injuries in people. The proper treatment of these fractures is important in order to recover complete mobility. The aim of this work was to investigate if screw positioning in plates for proximal tibial fractures can affect the stability of the system, and if it can consequently influence the patient healing time. In fact, a more stable construct could allow the reduction of the non-weight-bearing period and consequently speed up the healing process. For that purpose, virtual models of fractured bone/plate assemblies were created, and numerical simulations were performed to evaluate the reaction forces and the maximum value of the contact pressure at the screw/bo…
Quasi-Fractional Models of Human Tendons Hereditariness
2018
In this study, the authors, after collecting a series of experimental evidences following a creep and relaxation tendon campaign, propose a non-linear model of the viscoelastic behavior of the tendons. The ligaments investigated are the patellars and the hamstrings. The analytical model proposed by the authors aims to explain the non-linear hereditary behavior of these tissues and proposes an approach with which to develop a hereditary fractional-order non-linear model.
Intra-Articular Injection of Botulinum Toxin for the Treatment of Knee Osteoarthritis: A Systematic Review of Randomized Controlled Trials
2023
The purpose of the present paper was to review the available evidence on intra-articular botulinum toxin (BTX) injection in the treatment of knee osteoarthritis and to compare it to other conservative treatment options. A systematic review of the literature was performed on the PubMed, Scopus, Cochrane Library, Web of Science, Pedro and Research Gate databases with the following inclusion criteria: (1) randomized controlled trials (RCTs), (2) written in the English language, and (3) published on indexed journals in the last 20 years (2001–2021) dealing with the use of BTX intra-articular injection for the treatment of knee OA. The risk of bias was assessed using the Cochrane Risk of Bias to…
Purification of Nano-Porous Silicon for Biomedical Applications
2011
Recently, various bio-medical applications of nanoporous silicon (np-Si) have been suggested. This work investigates the biocompatibility of np-Si particles taking into account hazardous residua confined in the pores after preparation. The emphasis is on the potential application of such particles as oxygen photosensitizer for photodynamic therapy of cancer, which requires both negligible toxicity of np-Si particles in darkness and a high photo-cyto-toxic effect due to generation of singlet oxygen under illumination. Considerable amounts of water soluble toxic impurities are found to be present in the nanoporous shell of micrometer-sized np-Si particles immediately after their preparation b…
Manipulation of emitted light by structured lead halide perovskite nanocrystals for photonics applications
2021
Historically, active materials in photonic integrated circuits (PICs) have been implemented using III-V semiconductors, glasses, and ferroelectrics doped with rare-earth ions. However, there is a low-cost alternative based on (nano)materials synthesized using colloidal chemistry techniques. Their use in colloidal suspensions allows for the easy integration into any optical architecture via coating or printing techniques. The structure of perovskite nanocrystals (PNCs) are compounds with general formula ABX3, being A an inorganic or organic bulky cation, B a metal cation such as Pb2+ or Sn2+ and X the halide anion. In this context, all inorganic CsPbX3 (with X = Cl, Br, I) PNCs have recently…
What is immersive journalism?
2020
Immersive technologies are opening gateways to virtual realities that might change journalism forever. In the virtual world, journalism balances on the edge between imaginary approaches to fact-based creation and extended options for fakes. The journalistic maneuverings between reality and virtual reality are particularly intriguing to work with because they put the truth-seeking values of journalism into play. How can immersive technologies be applied to improve meaningful reporting and investigate storytelling in journalism? How can skills and knowledge of virtual reality empower news professionals? And how can journalism codes of ethics help shape the new platforms, shape a future in whi…
The Major Heat Shock Proteins, Hsp70 and Hsp90, in 2-Methoxyestradiol-Mediated Osteosarcoma Cell Death Model
2020
2-Methoxyestradiol is one of the natural 17&beta