Search results for "Arabitol"

showing 2 items of 2 documents

New hypoglycaemic agents selected by molecular topology.

2003

Abstract New compounds showing hypoglycaemic activity have been designed through a computer aided method based on quantitative structure–activity relationship (QSAR) and molecular connectivity. After calculation of topological indices for a set of 89 compounds including active and inactive with regards to hypoglycaemic action, linear discriminant analysis was performed so that a useful model to predict such an activity was achieved. Later on, the discriminant model was applied on a huge database so that fourteen compounds were selected as potential new hypoglycaemics. From them, just five were finally selected for experimental test on expected hypoglycaemic activity. Among the selected comp…

Quantitative structure–activity relationshipMolecular StructureDiscriminant modelPharmaceutical ScienceQuantitative Structure-Activity RelationshipPharmacologyLinear discriminant analysischemistry.chemical_compoundTolbutamidechemistryArabitolDrug DesignmedicinePotencyHypoglycemic AgentsMolecular topologymedicine.drugInternational journal of pharmaceutics
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Effect of season and soil treatments on carbohydrate concentrations in Norway spruce (Picea abies) mycorrhizae

1998

We studied effects of season and soil treatments (watering, acidification, liming and combinations of these treatments) on soluble carbohydrates of mycorrhizal roots of Norway spruce (Picea abies (L.) Karst.). Arabinose, arabitol, fructose, glucose, inositol, lactose, mannitol, pinite, quinate, raffinose, shikimate, stachyose and trehalose were identified by HPLC. Concentrations of inositol, lactose and pinite were constant throughout the year, whereas concentrations of raffinose, stachyose and trehalose were higher in winter than in summer, and concentrations of glucose, fructose and mannitol increased from February to September. Soil acidification and liming had no effect on the annual me…

biologyPhysiologySoil acidificationFructosePicea abiesPlant Sciencebiology.organism_classificationcomplex mixturesStachyosechemistry.chemical_compoundAnimal scienceAgronomychemistryArabitolmedicineMannitolLactoseRaffinosemedicine.drugTree Physiology
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