Search results for "Array"

Identification of pathways involved in aneuploidy onset and its tolerance using a DNA microarray approach

2014

FRUIT QUALITY EVALUATION OF FOUR LOQUAT CULTIVARS GROWN IN SICILY

2011

Chemical (soluble solids content, titratable acidity, pH), morphological (weight, longitudinal and transversal diameter, thickness of the flesh, number of seeds, peel colour), and sensorial characteristics of four loquat cultivars (‘Algerie’, ‘Claudia’, ‘Nespolone di Trabia’ and ‘Sanfilippara’) from mature, organically-grown trees in Sicily, were analysed. The determinations were carried out by traditional instrumental techniques, by a panel test and by an electronic olfactory system. A panel of 10 trained judges was used to determine intensity of some attributes in the sensory profile of the different cultivars, while the electronic olfactory system was used to identify possible difference…

Suffix Array Construction on Multi-GPU Systems

2019

Suffix arrays are prevalent data structures being fundamental to a wide range of applications including bioinformatics, data compression, and information retrieval. Therefore, various algorithms for (parallel) suffix array construction both on CPUs and GPUs have been proposed over the years. Although providing significant speedup over their CPU-based counterparts, existing GPU implementations share a common disadvantage: input text sizes are limited by the scarce memory of a single GPU. In this paper, we overcome aforementioned memory limitations by exploiting multi-GPU nodes featuring fast NVLink interconnects. In order to achieve high performance for this communication-intensive task, we …

Efficient smart-camera accelerator: A configurable motion estimator dedicated to video codec

2013

Smart cameras are used in a large range of applications. Usually the smart cameras transmit the video or/and extracted information from the video scene, frequently on compressed format to fit with the application requirements. An efficient hardware accelerator that can be adapted and provide the required coding performances according to the events detected in the video, the available network bandwidth or user requirements, is therefore a key element for smart camera solutions. We propose in this paper to focus on a key part of the compression system: motion estimation. We have developed a flexible hardware implementation of the motion estimator based on FPGA component, fully compatible with…

Cytotoxicity of the bisphenolic honokiol from Magnolia officinalis against multiple drug-resistant tumor cells as determined by pharmacogenomics and …

2014

A main problem in oncology is the development of drug-resistance. Some plant-derived lignans are established in cancer therapy, e.g. the semisynthetic epipodophyllotoxins etoposide and teniposide. Their activity is, unfortunately, hampered by the ATP-binding cassette (ABC) efflux transporter, P-glycoprotein. Here, we investigated the bisphenolic honokiol derived from Magnolia officinalis. P-glycoprotein-overexpressing CEM/ADR5000 cells were not cross-resistant to honokiol, but MDA-MB-231 BRCP cells transfected with another ABC-transporter, BCRP, revealed 3-fold resistance. Further drug resistance mechanisms analyzed study was the tumor suppressor TP53 and the epidermal growth factor recepto…

Advanced time-stamped total data acquisition control front-end for MeV ion beam microscopy and proton beam writing

2013

Many ion-matter interactions exhibit [email protected] time dependences such as, fluorophore emission quenching and ion beam induced charge (IBIC). Conventional event-mode MeV ion microbeam data acquisition systems discard the time information. Here we describe a fast time-stamping data acquisition front-end based on the concurrent processing capabilities of a Field Programmable Gate Array (FPGA). The system is intended for MeV ion microscopy and MeV ion beam lithography. The speed of the system (>240,000 events s^-^1 for four analogue to digital converters (ADC)) is limited by the ADC throughput and data handling speed of the host computer.

An MDE Approach for Rapid Prototyping and Implementation of Dynamic Reconfigurable Systems

2015

This article presents a co-design methodology based on RecoMARTE, an extension to the well-known UML MARTE profile, which is used for the specification and automatic generation of Dynamic and Partially Reconfigurable Systems-on-Chip (DRSoC). This endeavor is part of a larger framework in which Model-Driven Engineering (MDE) techniques are extensively used for modeling and via model transformations, generating executable models, which are exploited by implementation tools to create reconfigurable systems. More specifically, the methodological aspects presented in this article are concerned with expediting the conception and implementation of the hardware platform and the integration of corre…

Viral fitness correlates with the magnitude and direction of the perturbation induced in the host’s transcriptome: the tobacco etch Potyvirus—tobacco…

2018

Determining the fitness of viral genotypes has become a standard practice in virology as it is essential to evaluate their evolutionary potential. Darwinian fitness, defined as the advantage of a given genotype with respect to a reference one, is a complex property that captures, in a single figure, differences in performance at every stage of viral infection. To what extent does viral fitness result from specific molecular interactions with host factors and regulatory networks during infection? Can we identify host genes in functional classes whose expression depends on viral fitness? Here, we compared the transcriptomes of tobacco plants infected with seven genotypes of tobacco etch potyv…

Study of $^{45}$Ar through (d, p) reaction at SPIRAL

2005

NESTER; International audience; The structure of the neutron-rich nucleus $^{45}$Ar has been investigated through the d($^{44}$Ar,$^{45}$Ar)p transfer reaction. Radioactive beam of $^{44}$Ar at 10 A MeV has been provided by the SPIRAL facility at GANIL. The protons corresponding to a neutron pick-up on bound or unbound states mechanism in $^{45}$Ar nuclei were detected at backward angles by the detector array MUST. The transfer-like ejectiles were detected in the SPEG spectrometer. Level scheme, spin assignments and spectroscopic factors have been deduced for $^{45}$Ar and compared to shell model predictions. These parameters will be subsequently used to infer (n, $\gamma$) cross sections i…

Liver X Receptor Regulates Arachidonic Acid Distribution and Eicosanoid Release in Human Macrophages

2013

Objective— Liver X receptors (LXRs) are oxysterol-activated nuclear receptors that are highly expressed in macrophages and regulate lipid homeostasis and inflammation. Among putative LXR target genes, lysophosphatidylcholine acyltransferase 3 (LPCAT3) involved in the Lands cycle controls the fatty acid composition at the sn-2 position of glycerophospholipids and, therefore, the availability of fatty acids, such as arachidonic acid (AA), used for eicosanoid synthesis. The aim of our study was to determine whether LXRs could regulate the Lands cycle in human macrophages, to assess the consequences in terms of lipid composition and inflammatory response, and to work out the relative contribut…