Search results for "Arum"

showing 10 items of 354 documents

Antiprotozoal and cysteine proteases inhibitory activity of dipeptidyl enoates

2018

A family of dipeptidyl enoates has been prepared and tested against the parasitic cysteine proteases rhodesain, cruzain and falcipain-2 related to sleeping sickness, Chagas disease and malaria, respectively. They have also been tested against human cathepsins B and L1 for selectivity. Dipeptidyl enoates resulted to be irreversible inhibitors of these enzymes. Some of the members of the family are very potent inhibitors of parasitic cysteine proteases displaying k2nd (M−1s−1) values of seven orders of magnitude. In vivo antiprotozoal testing was also performed. Inhibitors exhibited IC50 values in the micromolar range against Plasmodium falciparum, Trypanosoma brucei, Trypanosoma cruzi and ev…

0301 basic medicinesleeping sicknessClinical BiochemistryPharmaceutical Science01 natural sciencesBiochemistryCathepsin BinhibitorsDrug Discoverychemistry.chemical_classificationbiologyChemistryDipeptidesHep G2 CellsMolecular Docking SimulationCysteine EndopeptidasesBiochemistryAntiprotozoalMolecular MedicineChagas diseaseProteasesCell Survivalmedicine.drug_classPlasmodium falciparumTrypanosoma brucei bruceimalariaAntiprotozoal AgentsCysteine Proteinase InhibitorsTrypanosoma bruceicysteine proteasesInhibitory Concentration 50Structure-Activity Relationship03 medical and health sciencesparasitic diseasesmedicineHumansTrypanosoma cruziMolecular Biologychagas diseaseBinding Sites010405 organic chemistryOrganic ChemistryPlasmodium falciparumbiology.organism_classificationmedicine.diseaseProtein Structure Tertiary0104 chemical sciences030104 developmental biologyEnzymeCysteineBioorganic & Medicinal Chemistry
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Use of Botanicals to Suppress Different Stages of the Life Cycle of Fusarium graminearum

2019

Fusarium head blight (FHB) is one of the most important cereal diseases worldwide, causing yield losses and contamination of harvested products with mycotoxins. Fusarium graminearum is one of the most common FHB-causing species in wheat and barley cropping systems. We assessed the ability of different botanical extracts to suppress essential stages of the fungal life cycle using three strains of F. graminearum (FG0410, FG2113, and FG1145). The botanicals included aqueous extracts from white mustard (Sinapis alba) seed flour (Pure Yellow Mustard [PYM] and Tillecur [Ti]) as well as milled Chinese galls (CG). At 2% concentration (wt/vol), PYM and Ti completely inhibited growth of mycelium of …

2. Zero hunger0106 biological sciences0301 basic medicineFusariumBiological pest controlfood and beveragesPlant ScienceBiologyContaminationbiology.organism_classification01 natural sciencesDisease control03 medical and health scienceschemistry.chemical_compoundHorticulture030104 developmental biologychemistryMycologyYield (wine)Head blightBiological control; Botanicals; Disease control; Fusarium graminearum; MycologyMycotoxinAgronomy and Crop Science010606 plant biology & botanyPhytopathology®
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Pēterburgas Zinātņu akadēmijas rakstu krājumi Latvijas Universitātes Muzejā

2019

Latvijas Universitātes Muzeja Botānikas un mikoloģijas kolekcijās glabājas Pēterburgas Zinātņu akadēmijas 18. gs. beigās – 19. gs. sākumā izdotā rakstu krājuma 27 sējumi - Acta Academiae Scientiarum Imperialis Petropolitanae (12 sējumi) un Nova Acta Academiae Scientiarum Imperialis Petropolitanae (15 sējumi). Raksts satur informāciju par Pēterburgas Zinātņu akadēmijas izveidi un rakstu krājuma publikāciju visražīgākajiem autoriem.

Acta Academiae Scientiarum Imperialis PetropolitanaeThe Saint Petersburg Academy of SciencesPēterburgas Zinātņu akadēmijaNova Acta Academiae Scientiarum Imperialis Petropolitanaerakstu krājums:HUMANITIES and RELIGION::History and philosophy subjects::History subjects::History of science [Research Subject Categories]zinātņu vēsture
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Visiting Friends and Relatives (VFRs) travelers and imported malaria in the Palermo district (Sicily).

2014

Abstract Introduction. Although Italy has been malaria-free since 1970, the infection is commonly introduced into the country by travelers and immigrants from endemic areas. The term VFRs refers to immigrants from malaria-endemic countries who are regularly resident in a malaria-free area, and who travel to their countries of origin to visit friends and relatives (VFRs). This group is at special risk of malaria as they are unaware of having lost their transitory immunity to the disease. Methods. We conducted a retrospective study at the International Travelers Department of Palermo (Italy), examining records of malaria cases (67) reported over the period from 1998 to 2013. Results. VFRs rep…

AdultMaleAdolescentEmigrants and ImmigrantsFriendsSettore MED/42 - Igiene Generale E Applicatavisiting friendsand relativesYoung Adultparasitic diseasesHumansFamilyMalaria FalciparumChildSicilyAgedRetrospective StudiesVFRsvisiting friends and relatives imported malaria travelers Sicily VFRsTravellcsh:Public aspects of medicineInfantlcsh:RA1-1270Middle AgedMalariaChild PreschooltravelersFemaleimported malaria
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Metoclopramide and diphenhydramine in the treatment of hyperemesis gravidarum: effectiveness and predictors of rehospitalisation.

2007

Abstract Objectives Hyperemesis gravidarum (HG) is the second most common reason for hospitalisation during pregnancy. Since 2002, a new HG treatment protocol consisting of metoclopramide plus diphenhydramine was put in place at CHU Sainte-Justine, affiliated to University of Montreal, Quebec, Canada. The objectives of this study were to evaluate the effectiveness of this new HG protocol regarding length of hospitalisation for HG, rate of rehospitalisation, evolution of nausea and vomiting symptoms, and rate of adverse events. Study design A retrospective cohort study was conducted from 2002 to 2006 on the population of pregnant women diagnosed with HG, and treated at CHU Sainte-Justine wit…

AdultMetoclopramideAdolescentNauseamedicine.drug_classMetoclopramidePopulationPatient ReadmissionCohort StudiesHyperemesis gravidarumYoung AdultSex FactorsPregnancyHyperemesis GravidarumMorning sicknessmedicineAntiemeticHumanseducationRetrospective Studieseducation.field_of_studybusiness.industryDiphenhydraminePregnancy OutcomeObstetrics and GynecologyLength of Staymedicine.diseaseDiphenhydramineTreatment OutcomeReproductive MedicineAnesthesiaAntiemeticsDrug Therapy CombinationFemalemedicine.symptombusinessDroperidolmedicine.drugEuropean journal of obstetrics, gynecology, and reproductive biology
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PLASMODIUM DOMINAN DALAM NYAMUK ANOPHELES BETINA (Anopheles spp.) PADA BEBERAPA TEMPAT DI DISTRIK MANOKWARI BARAT

2018

Malaria contagious by mosquito Anopheles Betina bringing protozoa parasite in its body (Plasmodium). Plasmodium there are four specieses that is Plasmodium vivax, Plasmodium ovale, Plasmodium malariae and Plasmodium falciparum, but often becomes pathogen that is Plasmodium vivax and Plasmodium falciparum. As for intention of this research is to identify Plasmodium which is dominant at female Anopheles mosquito (Anopheles spp.) and knows distribution pattern of female Anopheles mosquito (Anopheles spp.) in some places in Districts Manokwari Barat.
 Based on research result done to four locations that is area Amban, Wosi, Sanggeng and Kota is found [by] 1024 mosquito tails. From the amou…

AedesbiologyCulexfungiparasitic diseasesPlasmodium vivaxAnophelesZoologyPlasmodium falciparumPlasmodium malariaebiology.organism_classificationPlasmodium ovalePlasmodiumJurnal Natural
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An adventive Panaeolus antillarum in Poland (Basidiomycota, Agaricales) with notes on its taxonomy, geographical distribution, and ecology

2014

Abstract Coprophilous fungus, Panaeolus antillarum rarely recorded in Europe, is reported here for the first time from the Augustow Plane, north-eastern Poland. This thermophilic species was found outdoors in August on horse dung mixed with straw. A chemical analysis did not confirm the presence of the psychoactive alkaloids in collected material. A complete description and illustration of the species based on Polish specimens are presented and notes on its taxonomy, ecology, world distribution and comparison with similar taxa — P. semiovatus var. semiovatus, P. semiovatus var. phalaenarum, and others are also provided.

Anellaria antillarumbiologyEcologyBasidiomycotaPolish mycobiotabiology.organism_classificationTaxoncoprophilous mushroomsBotanyAgaricalesTaxonomy (biology)GC-MSEcology Evolution Behavior and SystematicsPanaeolus antillarumCryptogamie Mycologie
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Evaluation of biological and antimicrobial properties of freeze-dried whey fermented by different strains ofLactobacillus plantarum

2018

The aim of this study was to evaluate the biological and antimicrobial activities of commercial freeze-dried whey fermented by lactic acid bacteria in order to valorize this high polluting liquid waste of the dairy industry. Freeze-dried whey was fermented by different strains of Lactobacillus plantarum (CECT 220, 221, 748) at three different times of fermentation (24, 48, 72 h). Afterwards, the extract was purified on centricon amicon with a cut-off of 3 kDa to obtain a permeate consisting of small bioactive compounds reported in the literature to show greater bioactivity. The purified and diluted samples were subjected to the biological and antimicrobial tests for the evaluation of antiox…

Antifungal AgentsMass SpectrometryIngredientchemistry.chemical_compound0404 agricultural biotechnologyPhenolsWheyFood sciencebiologyFungiFood preservationfood and beveragesBiological activity04 agricultural and veterinary sciencesGeneral Medicinebiology.organism_classificationAntimicrobial040401 food scienceLactic acidFreeze DryingchemistryFermentationPenicilliumFermentationLactobacillus plantarumLactobacillus plantarumFood ScienceFood & Function
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Whey fermented by using Lactobacillus plantarum strains: A promising approach to increase the shelf life of pita bread

2019

Nowadays, there is an increasing concern regarding the shelf life of food products, leading producers to research natural antimicrobial agents to use in food preparation. In this study, we evaluated the antifungal activity of Lactobacillus plantarum fermented whey and then added the whey during preparation of pita bread to study shelf-life improvement. The fermented whey showed a satisfactory inhibitory (antifungal) effect against Penicillium expansum and Penicillium brevicompactum strains: the minimum inhibitory and minimum fungicidal concentrations ranged from 3.9 to 39.0 g/L and from 62.5 to 250 g/L, respectively. Addition of fermented whey increased the shelf life of the pita bread. Aft…

Antifungal Agentsanimal structureswheyPenicillium brevicompactumShelf life03 medical and health sciencesfluids and secretionsFood PreservationGeneticsFood science030304 developmental biology0303 health sciencesbiologyChemistryantifungal activitydigestive oral and skin physiologyPenicilliumPenicillium strain0402 animal and dairy scienceFood preservationfood and beveragesBread04 agricultural and veterinary sciencesbiology.organism_classificationAntimicrobial040201 dairy & animal sciencepita breadFermentationPenicilliumshelf lifeAnimal Science and ZoologyFermentationPenicillium expansumLactobacillus plantarumLactobacillus plantarumFood ScienceJournal of Dairy Science
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Gamma delta T cells inhibit in vitro growth of the asexual blood stages of Plasmodium falciparum by a granule exocytosis-dependent cytotoxic pathway …

2004

Several reports have stated the ability of gamma delta T cells to inhibit the growth of the asexual blood stages of Plasmodium falciparum in vitro. However, little information is available about the mechanisms involved. In this study, in vitro systems were used to study the role of the granule exocytosis-dependent cytotoxic pathway in the growth inhibition/killing of P. falciparum by human gamma delta T cells. Our results show that the inhibition requires cell-to-cell contact and that gamma delta T cells kill the asexual blood stages of P. falciparum through a granule exocytosis-dependent cytotoxic pathway after recognition of certain ligands or molecules expressed on the surface of infecte…

Antigens Differentiation T-LymphocytePore Forming Cytotoxic ProteinsT-LymphocytesImmunologyPlasmodium falciparumReceptors Antigen T-CellCell CommunicationCytoplasmic GranulesExocytosischemistry.chemical_compoundImmunology and AllergyCytotoxic T cellAnimalsHumansRNA MessengerGranulysinMembrane GlycoproteinsbiologyPerforinDegranulationPlasmodium falciparumbiology.organism_classificationIn vitroCell biologyPerforinchemistrybiology.proteinGrowth inhibitionCD8European journal of immunology
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