Search results for "Asarum"

showing 2 items of 2 documents

Major trends in stem anatomy and growth forms in the perianth-bearing Piperales, with special focus on Aristolochia.

2014

International audience; BACKGROUND AND AIMS: The order Piperales has the highest diversity of growth forms among the earliest angiosperm lineages, including trees, shrubs, climbers and herbs. However, within the perianth-bearing Piperales (Asarum, Saruma, Lactoris, Hydnora, Prosopanche, Thottea and Aristolochia), climbing species only occur in the most species-rich genus Aristolochia. This study traces anatomical and morphological traits among these lineages, to detect trends in growth form evolution and developmental processes. METHODS: Transverse stem sections of different developmental stages of representatives of Asarum, Saruma, Lactoris, Hydnora, Thottea and Aristolochia were compared …

0106 biological sciencesLactorisanatomyAristolochiaceaeHeterochronySarumaPlant Science010603 evolutionary biology01 natural sciencesSecondary woodinessbiomechanicsAristolochiaPiperalesgrowth formLactorisPerianth-bearing PiperalesheterochronyBotany[SDE.BE.EVO]Environmental Sciences/Biodiversity and Ecology/domain_sde.be.evoHydnoraBiomechanicsGrowth formperianth-bearing PiperalesAsarumsecondary woodinessbiologyPlant StemsThotteaThotteaHydnoraAnatomyOriginal ArticlesAristolochiabiology.organism_classificationBiological EvolutionBiomechanical PhenomenaSaruma[SDE]Environmental SciencesAristolochiaceaePerianth[SDE.BE]Environmental Sciences/Biodiversity and EcologyAnatomy010606 plant biology & botany
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Medicinally Used Asarum Species: High-Resolution LC-MS Analysis of Aristolochic Acid Analogs and In vitro Toxicity Screening in HK-2 Cells

2017

Species of Asarum are used in traditional Chinese medicine and, similar to members of the genus Aristolochia, they contain aristolochic acid analogs (AAAs). These compounds are known for their nephrotoxic and carcinogenic effects. So far, the phytochemistry and nephrotoxicity of species of Asarum is not well studied. A high-resolution LC-MS-based metabolomic approach was used to study the phytochemical variation in medicinally used Asarum species. The cytotoxicity of the samples was assessed using human kidney (HK-2) cells. The majority of samples contained potentially nephrotoxic AAAs, including 9-methoxy aristolactam (AL) IV, AL I, and AL IV. These compounds were present in methanol as we…

PharmacologyAsarumlcsh:Therapeutics. Pharmacologynephrotoxicityaristolactamlcsh:RM1-950Pharmacology (medical)metabolomicsLC-MSFrontiers in Pharmacology
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