Search results for "Ascite"

showing 10 items of 100 documents

The impact of patient and tumour baseline characteristics on the overall survival of patients with advanced hepatocellular carcinoma treated with sor…

2013

Abstract Background Impact of patient and tumour baseline characteristics on the overall survival is not well characterized in patients with advanced hepatocellular carcinoma (HCC) treated with sorafenib. Aims/methods Univariate/multivariate analyses were conducted to identify retrospectively the impact of baseline characteristics on the survival of 110 patients with advanced HCC treated with sorafenib. Results Median survival of the whole cohort was 6.7 months, median survival in Child-Pugh A, B, C patients was 10.5, 6.1 and 3.0 months and median survival of patients with Barcelona Clinic Liver Cancer (BCLC) stage C/D was 6.8/2.6 months. Presence of ascites, presence of macrovascular invas…

OncologySorafenibAdultMaleNiacinamidemedicine.medical_specialtyCirrhosisCarcinoma HepatocellularAntineoplastic AgentsSeverity of Illness IndexYoung AdultInternal medicineAscitesmedicineHumansAgedRetrospective StudiesAged 80 and overHepatologyPerformance statusbusiness.industryPhenylurea CompoundsLiver NeoplasmsGastroenterologyMiddle AgedSorafenibmedicine.diseasePrognosisSurvival Analysisdigestive system diseasesBCLC StageTreatment OutcomeHepatocellular carcinomaMultivariate AnalysisFemaleLiver functionmedicine.symptomLiver cancerbusinessmedicine.drugDigestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver
researchProduct

Hepatocellular carcinoma and synchronous liver metastases from colorectal cancer in cirrhosis: A case report.

2013

A 68-year-old Caucasian man with hepatitis C virus-related cirrhosis was admitted to our Unit in February 2010 for a diagnostic evaluation of three centimetric hypoechoic focal liver lesions detected by regular surveillance ultrasound. The subsequent computer tomography (CT) led to a diagnosis of unifocal hepatocellular carcinoma (HCC) in VI hepatic segment, defined the other two nodules in the VI and VII segment as suspected metastases, and showed a luminal narrowing with marked segmental circumferential thickening of the hepatic flexure of the colon. Colonoscopy detected an ulcerated, bleeding and stricturing lesion at the hepatic flexure, which was subsequently defined as adenocarcinoma …

Pathologymedicine.medical_specialtyCirrhosisHepatologymedicine.diagnostic_testbusiness.industryColorectal cancerCase Reportcolorectal cancerHepatitis Chepatocellular carcinomamedicine.diseaseMetastasisHepatocellular carcinomaLiver biopsyAscitesmedicineAdenocarcinomamedicine.symptombusiness
researchProduct

Congenital Plaque-Type Glomuvenous Malformations Associated with Fetal Pleural Effusion and Ascites

2010

Glomuvenous malformations are hereditary vascular anomalies, usually without extracutaneous involvement. We report two cases of extensive thoracic plaque-type glomuvenous malformation in newborns who had previously been diagnosed in utero with pleural effusion and ascites, suggesting a pathogenic link between the two conditions.

Pathologymedicine.medical_specialtyExtramuralbusiness.industryPleural effusionDermatologymedicine.diseaseGlomuvenous malformationIn uteroParagangliomaPediatrics Perinatology and Child HealthAscitesmedicinePlaque typeRadiologymedicine.symptomFetal pleural effusionbusinessPediatric Dermatology
researchProduct

Targeting the mitochondrial pathway to induce apoptosis/necrosis through ROS by a newly developed Schiff’s base to overcome MDR in cancer

2011

Abstract Multidrug resistance (MDR) in cancer, a major obstacle to successful application of cancer chemotherapy, is often characterized by over-expression of multidrug resistance-related proteins such as MRP1, P-gp or elevated glutathione (GSH) level. Efflux of drugs by functional P-gp, MRP1 and elevated GSH level can confer resistance to apoptosis induced by a range of different stimuli. Therefore, it is necessary to develop new cell death inducers with relatively lower toxicity toward non-malignant cells that can overcome MDR by induction of apoptotic or non-apoptotic cell death pathways. Herein we report the synthesis and spectroscopic characterization of a GSH depleting, redox active S…

Programmed cell deathMagnetic Resonance SpectroscopyNecrosisApoptosisMitochondrionBiologymedicine.disease_causeBiochemistryEhrlich ascites carcinomaMiceNecrosisCell Line TumorNeoplasmsSpectroscopy Fourier Transform InfraredmedicineAnimalsCytotoxic T cellCytotoxicitySchiff BasesCalpainCaspase 3General MedicineFlow CytometryGlutathioneMitochondriaBiochemistryDrug Resistance NeoplasmApoptosisCancer researchCalciumSpectrophotometry Ultravioletmedicine.symptomReactive Oxygen SpeciesOxidative stressBiochimie
researchProduct

Fascite cranio-cervicale, dal quadro clinico al trattamento: esperienza personale

2009

Settore MED/31 - OtorinolaringoiatriaFasciteSettore MED/32 - Audiologia
researchProduct

Managment clinico e chirurgico delle infezioni profonde del collo

2009

La fascite necrotizzante (FN) è un’infezione dei tessuti molli caratterizzata da necrosi diffusa a rapida progressione dei tessuti sottocutanei e delle fasce ad essi annessi, potenzialmente letale. L’incidenza varia a seconda della localizzazione e tra tutte quella cranio-cervicale (FNCC) si presenta in 4/1000 casi di FN l’anno. Se pur rara negli ultimi anni si è assistito ad una maggiore evidenziazione clinica; ciò è da ascrivere ad una transitoria immunodepressione legata a malattie sistemiche in grado di compromettere i meccanismi di fagocitosi; I processi flogistici in grado di evolvere in FN sono prevalentemente infezioni dentarie (23%), ascessi peritonsillari (15%) ed infezioni a live…

Settore MED/31 - OtorinolaringoiatriaInfezioni profonde del collo Fascite necrotizzante
researchProduct

EFFICACIA DEL TRATTAMENTO CON ONDE D'URTO EXTRACORPOREE (ESWT) ED ESERCIZI DI STRETCHING NELLA FASCITE PLANTARE CRONICA

2009

Settore MED/34 - Medicina Fisica E RiabilitativaONDE D'URTO FASCITE PLANTARE
researchProduct

L'efficacia della tecar-terapia nel trattamento della fascite plantare.

2010

Settore MED/34 - Medicina Fisica E Riabilitativaterapia fisica tecar-terapia fascite plantare
researchProduct

Patologie da stress della volta plantare

2009

Stress della volta plantare malattia di Ledderhose fascite plantare rotture della fascia plantareSettore MED/33 - Malattie Apparato Locomotore
researchProduct

Sonographic evidence of intraperitoneal fluid. An experimental study and its clinical implications.

1984

In order to evaluate the sensitivity of ultrasound to intraperitoneal fluid, such as ascites or blood, an experimental study was performed in the pig. Various amounts of fluid were injected into the peritoneal cavity to investigate distribution and diagnostic criteria in different positions. As little as 10 ml of fluid was visualized around the urinary bladder in an upright position. In the supine position, 20 ml could be detected around the bladder and 30 ml around the liver. The injection of at least 60 ml resulted in a pattern of free-floating bowel loops. The sonographic findings of fluid distribution were correlated to radiological studies. As different amounts of fluid produce charact…

X ray radiographyPathologymedicine.medical_specialtySupine positionUrinary bladderbusiness.industrySwineUltrasoundPostureAscitesPeritoneal cavitymedicine.anatomical_structurePeritoneumPediatrics Perinatology and Child HealthAscitesmedicineAnimalsAscitic FluidRadiology Nuclear Medicine and imagingmedicine.symptomNuclear medicinebusinessFluid volumeUltrasonographyPediatric radiology
researchProduct