Search results for "Asses"

showing 10 items of 5931 documents

Effect of dulaglutide on cognitive impairment in type 2 diabetes: an exploratory analysis of the REWIND trial

2020

Digital

AdultMalemedicine.medical_specialtyRecombinant Fusion ProteinsGlucagon-Like Peptides030209 endocrinology & metabolismType 2 diabetesPlacebolaw.invention03 medical and health sciences0302 clinical medicineDouble-Blind MethodRandomized controlled triallawInternal medicinemedicineHumansHypoglycemic AgentsCognitive DysfunctionRisk factorAgedbusiness.industryHazard ratioMontreal Cognitive AssessmentMiddle Agedmedicine.diseaseImmunoglobulin Fc FragmentsTreatment OutcomeDiabetes Mellitus Type 2Digit symbol substitution testFemaleDulaglutideNeurology (clinical)business030217 neurology & neurosurgerymedicine.drug
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RhinAsthma patient perspective: a short daily asthma and rhinitis QoL assessment.

2012

Background The present study aimed to develop a short validated patient-completed questionnaire, the RhinAsthma Patient Perspective (RAPP), to assess the health-related quality of life (HRQoL) in patients with asthma and comorbid allergic rhinitis in clinical practice. Methods A provisional RAPP questionnaire was formed from candidate items identified through retrospective analysis of 333 RHINASTHMA questionnaires. This was then tested on 150 asthma patients with allergic rhinitis. Results Psychometric analyses identified eight items fitting a unidimensional model to form RAPP. Internal consistency (Cronbach's alpha coefficient > 0.8) and agreement with RHINASTHMA (r = −0.31, P = 0.0001) we…

AdultMalemedicine.medical_specialtyRhinitis Allergic PerennialPsychometricsAdolescentPsychometricsVisual analogue scaleassessmentConcordanceImmunologyPopulationSettore MED/10 - Malattie Dell'Apparato RespiratoriorhinitisAllergicCronbach's alphaQuality of lifeSurveys and Questionnaires80 and overmedicineSurveys and QuestionnaireImmunology and AllergyHumansdaily practiceeducationAsthmaAgedAged 80 and overeducation.field_of_studybusiness.industryassessment; asthma; daily practice; quality of life; rhinitis; Adolescent; Adult; Aged; Aged 80 and over; Asthma; Female; Humans; Male; Middle Aged; Psychometrics; Rhinitis Allergic; Rhinitis Allergic Perennial; Quality of Life; Surveys and Questionnaires; Immunology and Allergy; ImmunologyMiddle Agedmedicine.diseasePerennialRhinitis AllergichumanitiesAsthmarhinitiConvergent validityassessment; asthma; daily practice; quality of life; rhinitisPhysical therapyQuality of LifeFemalebusinessPsychometricHumanAllergy
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Systematic retrospective study of 64 patients with anti-Mi2 dermatomyositis: A classic skin rash with a necrotizing myositis and high risk of maligna…

2020

AdultMalemedicine.medical_specialtyRisk of malignancyMEDLINEDermatologyRisk AssessmentDermatomyositisNecrosisRisk FactorsNeoplasmsmedicineHumansMuscle SkeletalAgedAutoantibodiesRetrospective StudiesSkinbusiness.industryIncidenceNecrotizing myositisRetrospective cohort studyExanthemaMiddle AgedDermatomyositisPrognosismedicine.diseaseDermatologyRashFemalemedicine.symptombusinessMi-2 Nucleosome Remodeling and Deacetylase ComplexJournal of the American Academy of Dermatology
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Clinical verification of a unilateral otolith test.

1992

Abstract In a previous study13 we reported promising results for a new test to differentiate in vivo unilateral otolith functions. That study pointed to a need for further validation on known pathological cases. In this presentation we will detail the results gathered on a group of clinically verified vestibular defectives (verum) and a normal (control) group. The subjects in the verum group were former patients of the ENT clinic of the university hospital. These subjects had usually suffered from neurinoma of the VIIth cranial nerve or inner ear infections. All had required surgical intervention including removal of the vestibular system. The patients were contacted usually two or more yea…

AdultMalemedicine.medical_specialtyRotationAerospace EngineeringVestibular lossOtolithic MembraneTask Performance and Analysisotorhinolaryngologic diseasesmedicineHumansPathologicalOtolithAgedVestibular systembusiness.industryMiddle AgedVestibular Function TestsUniversity hospitalProprioceptionTest (assessment)Surgerymedicine.anatomical_structurePostoperative diagnosisEar InnerMedical trainingFemalesense organsDisease SusceptibilitySpace Motion SicknessbusinessActa astronautica
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Defining and predicting functional outcome in schizophrenia and schizophrenia spectrum disorders.

2009

Abstract Background: To assess criteria and to identify predictive factors for functional outcome. The criteria should cover all domains proposed by the Remission in Schizophrenia Working Group. Method: PANSS ratings were used to evaluate the symptomatic treatment outcome of 262 inpatients with schizophrenia spectrum disorders within a naturalistic multicenter trial. Functional remission was defined as a GAF score > 61 (Global Assessment of Functioning Scale), SOFAS score > 61 (Social and Occupational Functioning Scale) and a SF-36 mental health subscore > 40 (Medical Outcomes Study—Short Form Health Survey). Multivariate logistic regression and CART analyses were used to determine valid cl…

AdultMalemedicine.medical_specialtySF-36Global Assessment of FunctioningNeuropsychological TestsLogistic regressionSeverity of Illness IndexDevelopmental psychology03 medical and health sciencesYoung Adult0302 clinical medicinePredictive Value of TestsRecurrenceInternal medicineMulticenter trialSeverity of illnessOutcome Assessment Health CaremedicineHumansBiological PsychiatryRetrospective StudiesPsychiatric Status Rating ScalesMiddle Agedmedicine.disease030227 psychiatry3. Good healthPsychiatry and Mental healthPsychotic DisordersROC CurveSchizophreniaPredictive value of testsSchizophreniaRegression AnalysisFemaleSchizophrenic PsychologyPsychologyPsychosocial030217 neurology & neurosurgeryFollow-Up StudiesSchizophrenia research
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Ultrasonic Echo Intensity as a New Noninvasive In Vivo Biomarker of Frailty

2017

Objectives To investigate whether muscle quality based on echo intensity (EI) is associated with muscle strength (MS) and correlates with risk of frailty in elderly outpatients. Design Cross-sectional, experimental study. Setting Outpatient clinic. Participants Individuals aged 20 to 90 (N = 112). Individuals aged 20 to 59 participated as controls. Those aged 60 and older participated in the experimental group and were subdivided into robust, prefrail, and frail according to the Fried frailty criteria. Measurements EI, muscle thickness (MT), and subcutaneous fat thickness (SFT) of the anterior compartment of the thigh were measured using ultrasound images. MS was quantified using a hand dyn…

AdultMalemedicine.medical_specialtySignificant negative correlationYoung Adult03 medical and health sciences0302 clinical medicineQuality of lifeIn vivoInternal medicineHumansOutpatient clinicMedicineMuscle Strength030212 general & internal medicineElderly adultsGeriatric AssessmentAgedUltrasonographyAged 80 and overFrailtybusiness.industryUltrasoundMiddle AgedCross-Sectional StudiesPhysical therapyBiomarker (medicine)FemaleGeriatrics and Gerontologybusiness030217 neurology & neurosurgeryEcho intensityJournal of the American Geriatrics Society
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Evaluation of the Upper Limb Lymphatic System: A Prospective Lymphoscintigraphic Study in Melanoma Patients and Healthy Controls

2016

Background Current research on the upper limb lymphatic system mainly studies breast cancer patients with unilateral lymphedema. Without preoperative lymphoscintigraphy, the contralateral limb is used as a control, assuming that it is functionally intact. Few lymphoscintigraphic studies investigate patients before any axillary surgery. The purpose of this study was to evaluate, through lymphoscintigraphy, the preoperative condition of the upper limb lymphatic system in melanoma patients and healthy controls. Methods Two groups were studied: the study group (16 patients with trunk/upper limb melanoma candidates for axillary sentinel lymph node biopsy) and the control group (10 healthy volunt…

AdultMalemedicine.medical_specialtySkin NeoplasmsSentinel lymph node030230 surgeryRisk AssessmentLymphatic SystemUpper Extremity03 medical and health sciencesPostoperative Complications0302 clinical medicineBreast cancerPreoperative CareHumansMedicineProspective StudiesLymphedemaSkin NeoplasmProspective cohort studyMelanomaAgedbusiness.industrySentinel Lymph Node BiopsyMiddle Agedmedicine.diseaseTrunkSurgeryAxillaProspective StudieLymphedemamedicine.anatomical_structureLymphatic systemCase-Control Studies030220 oncology & carcinogenesisAxillaUpper limbSurgeryFemaleRadiologyPostoperative ComplicationbusinessCase-Control StudieLymphoscintigraphyHuman
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Sociodemographic, Lifestyle and Medical Factors Associated with Helicobacter Pylori Infection

2020

Background and Aims: The prevalence of Helicobacter pylori (H. pylori) infection is higher in developing countries and is often linked to lower socioeconomic status. Few studies have investigated the association between H. pylori and individual level characteristics in Europe, where several countries have a high prevalence of H. pylori infection. The study aimed to identify risk factors for H. pylori infection among adults in a large clinical trial in Latvia.
 Methods: 1,855 participants (40-64 years) of the “Multicenter randomized study of H. pylori eradication and pepsinogen testing for prevention of gastric cancer mortality” (GISTAR study) in Latvia tested for H. pylori IgG antibodi…

AdultMalemedicine.medical_specialtySocial Determinants of HealthBinge drinkingDiseaseRisk AssessmentBinge DrinkingHelicobacter Infectionslaw.inventionRandomized controlled trialRisk FactorslawInternal medicinemedicineHumansLife StyleSocioeconomic statusRandomized Controlled Trials as TopicUnivariate analysisHelicobacter pyloribiologybusiness.industrySmokingGastroenterologyOdds ratioMiddle AgedHelicobacter pyloribiology.organism_classificationLatviaDietClinical trialCross-Sectional StudiesSocioeconomic FactorsFemalebusinessJournal of Gastrointestinal and Liver Diseases
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Cataracts and statins. A disproportionality analysis using data from VigiBase.

2019

The basis of the association between statin use and cataract has been explored using the World Health Organization (WHO) global database of individual case safety reports (ICSRs) for drug monitoring (VigiBase) through January 2019. The reporting odds ratios (RORs) as a measure of disproportionality for reported cataracts and individual statins have been calculated. Subgroup analyses according statin lipophilicity, sex, and age groups have been performed. Moreover, RORs have been calculated for non-statin lipid lowering drugs. An increased disproportionality have been found for most individual statins lovastatin: [ROR: 14.80, 95% confidence interval (CI): 13.30, 16.46)], atorvastatin (ROR: 3…

AdultMalemedicine.medical_specialtyStatinAdolescentmedicine.drug_classAtorvastatin010501 environmental sciencesToxicology030226 pharmacology & pharmacy01 natural sciencesRisk AssessmentCataract03 medical and health sciencesPharmacovigilanceYoung Adult0302 clinical medicineEzetimibeInternal medicinemedicineOdds RatioAdverse Drug Reaction Reporting SystemsHumansRosuvastatinChild0105 earth and related environmental sciencesAgedAged 80 and overbusiness.industryIncidenceGeneral MedicineOdds ratioMiddle AgedSimvastatinFemaleDrug MonitoringHydroxymethylglutaryl-CoA Reductase InhibitorsbusinessPravastatinmedicine.drugFluvastatinRegulatory toxicology and pharmacology : RTP
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Evaluation of surgical decision making and resulting outcome in patients with highly eloquent glioblastoma: Results of a multicenter assessment.

2017

Treatment of glioblastoma(GB) patients amenable only for a subtotal resection(STR) is controversial. Since outcome of patients is affected by surgical management, our aim was to assess surgical decision making and resulting outcome in patients with highly eloquent GBs.We retrospectively assessed GB patients with intended sub-total resection (STR) or stereotactic biopsy (STX) of 3 neurooncological centers operated between 2008 and 2013. A volumetric assessment of overall extent of resection(oEoR), presence of complications, new permanent neurological deficits(nPNDs) was performed. A central reviewer reassessed all cases blinded and gave recommendation on surgical management and on a potentia…

AdultMalemedicine.medical_specialtyStereotactic biopsyAdolescentClinical Decision-MakingExtent of resectionNeurosurgical Procedures03 medical and health sciencesYoung Adult0302 clinical medicinemedicineHumansIn patientAgedRetrospective StudiesAged 80 and overPreoperative planningmedicine.diagnostic_testbusiness.industryBrain NeoplasmsCentral ReviewerSubtotal ResectionGeneral MedicineMiddle Agedmedicine.diseaseSurgeryOutcome and Process Assessment Health Care030220 oncology & carcinogenesisNear total resectionSurgeryFemaleNeurology (clinical)businessGlioblastoma030217 neurology & neurosurgeryGlioblastomaClinical neurology and neurosurgery
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