Search results for "Asymmetric"

ChemInform Abstract: N1-Functionalized Indole-Phosphane Oxazoline (IndPHOX) Ligands in Asymmetric Allylic Substitution Reactions.

2012

N-Functionalized IndPHOX ligands bearing various groups have been synthesized and the effects of the N1-substituent on the reaction rate, yield, and asymmetric induction in a palladium-catalyzed allylic substitution reaction are reported. The presence of an oxygen atom in the ligands, namely an N-MOM or N-THP group, led to enhancement of the enantioselectivity in the allylic amination reaction. In addition, a ligand with a chiral oxazoline ring at C-1 and a phosphane substituent at C-2 provided high enantioselectivity in good yield in an asymmetric allylic alkylation reaction.

N‐Heterocyclic Carbene Catalyzed Asymmetric Synthesis of Pentacyclic Spirooxindoles via [3+3] Annulations of Isatin‐Derived Enals and Cyclic N‐Sulfon…

2019

Recyclable Heterogeneous and Low-Loading Homogeneous Chiral Imidazolidinone Catalysts for α-Alkylation of Aldehydes

2014

Two polystyrene-supported and six homogeneous MacMillan imidazolidinone catalysts were prepared and tested for the asymmetric α-alkylation of propanal with benzodithiolylium tetrafluoroborate. The chiral imidazolidinone was linked to polystyrene through the N-3 atom or through the phenyl ring and their catalytic activity was compared with that of their unsupported precursors. This comparison has allowed us to find an unsupported catalyst that displays high catalytic activity down to 5 or 2 mol % at room temperature with a high level of enantioselectivity also when used with hexanal and 3-phenylpropanal. In addition, one of the heterogeneous materials was revealed to be highly recyclable for…

Catalytic Enantioselective Conjugate Alkynylation of α,β-Unsaturated 1,1,1-Trifluoromethyl Ketones with Terminal Alkynes.

2016

The first catalytic enantioselective conjugate alkynylation of α,β-unsaturated 1,1,1-trifluoromethyl ketones has been carried out. Terminal alkynes and 1,3-diynes were treated with trifluoromethyl ketones in the presence of a low catalytic load of a CuI-MeOBIPHEP complex (2.5 mol %) and triethylamine (10 mol %) to give the corresponding trifluoromethyl ketones bearing a propargylic stereogenic center at the β position with good yields and excellent enantiomeric excesses in most of the cases. No 1,2-addition products were formed under the reaction conditions. The procedure showed broad substrate scope for alkyne, diyne, and enone. A rationale for the observed stereochemistry has been provide…

Cascaded Multilevel Inverter-Based Asymmetric Static Synchronous Compensator of Reactive Power

2022

The topology of the static synchronous compensator of reactive power for a low-voltage three-phase utility grid capable of asymmetric reactive power compensation in grid phases has been proposed and analysed. It is implemented using separate, independent cascaded H-bridge multilevel inverters for each phase. Every inverter includes two H-bridge cascades. The first cascade operating at grid frequency is implemented using thyristors, and the second one—operating at high frequency is based on the high-speed MOSFET transistors. The investigation shows that the proposed compensator is able to compensate the reactive power in a low-voltage three-phase grid when phases are loaded by highly asymmet…

Nonlinear elliptic equations with asymmetric asymptotic behavior at $pminfty$

2016

We consider a nonlinear, nonhomogeneous Dirichlet problem with reaction which is asymptotically superlinear at $+infty$ and sublinear at $-infty$. Using minimax methods together with suitable truncation techniques and Morse theory, we show that the problem has at least three nontrivial solutions one of which is negative.

Totally asymmetric exclusion process fed by using a non-Poissonian clock

2015

In this article we consider the one-dimensional totally asymmetric open-boundary exclusion process fed by a process with power-law-distributed waiting times. More specifically, we use a modified Pareto distribution to define the jump rate for jumps into the system. We then characterize the propagation of fluctuations through the system by kinetic Monte Carlo simulations and by numerical evaluation of the steady-state partition function. peerReviewed

On the classification of mapping class actions on Thurston's asymmetric metric

2011

AbstractWe study the action of the elements of the mapping class group of a surface of finite type on the Teichmüller space of that surface equipped with Thurston's asymmetric metric. We classify such actions as elliptic, parabolic, hyperbolic and pseudo-hyperbolic, depending on whether the translation distance of such an element is zero or positive and whether the value of this translation distance is attained or not, and we relate these four types to Thurston's classification of mapping class elements. The study is parallel to the one made by Bers in the setting of Teichmüller space equipped with Teichmüller's metric, and to the one made by Daskalopoulos and Wentworth in the setting of Te…

Iron metabolism markers and l-arginine derivatives in coronary artery disease : highlighting, assessment and role of oxidative stress in acute myocar…

2015

Myocardial infarction (MI) is mostly caused by complications of atherosclerosis, whose the development would be initiated by a dysfunction of the vascular endothelium, characterized by an inflammatory condition and oxidative stress.In this pathogenesis, iron interacts at different levels and also has a major role in the development of endothelial dysfunction. Hepcidin and erythroferrone (discovered earlier as the myonectin/CTRP 15) participate in a major way in regulating certain stages of iron metabolism.Asymmetric dimethylarginine (ADMA), a marker of endothelial dysfunction is associated with most cardiovascular risk factors. Symmetrical dimethyl-arginine (SDMA), its stereoisomer, has an …

Synergistic enhancement via plasmonic nanoplate-bacteria-nanorod supercrystals for highly efficient SERS sensing of food-borne bacteria

2017

Bio-sensing techniques utilizing metallic nanoparticles as a probe have gained more and more attention and play today an important role in the detection of bacteria. To date, although several sensing materials have been tested, there is still a long way to go to achieve a fast, low-cost, ultrasensitive and multifunctional substrate suitable for a universal biosensor for detection of bacterial cells. Here, we report a novel probe design based on anisotropic plasmonic nanoparticles organized to a biocompatible 3D bio-inorganic scaffold, i.e., nanoplate-bacteria-nanorod supercrystals (NBNS) with extremely high surface-enhanced Raman spectroscopic (SERS) activity as a model of synergistic plasm…