Search results for "Authorization"
showing 10 items of 32 documents
Enhancing Privacy and Authorization Control Scalability in the Grid through Ontologies
2009
The use of data Grids for sharing relevant data has proven to be successful in many research disciplines. However, the use of these environments when personal data are involved (such as in health) is reduced due to its lack of trust. There are many approaches that provide encrypted storages and key shares to prevent the access from unauthorized users. However, these approaches are additional layers that should be managed along with the authorization policies. We present in this paper a privacy-enhancing technique that uses encryption and relates to the structure of the data and their organizations, providing a natural way to propagate authorization and also a framework that fits with many u…
Regulatory evaluation of Glybera in Europe — two committees, one mission
2013
Representing the first gene therapy to be approved in the Western world, alipogene tiparvovec (Glybera; Uniqure) has recently been said to have had a “substantial impact from a regulatory perspective” (Nature Rev. Drug Discov. 11, 664; 2012) 1 . The therapy was granted marketing authorization in the European Union for the treatment of lipoprotein lipase deficiency, which results in a clinically heterogeneous condition with a risk of potentially life-threatening pancreatitis 2 , at the end of 2012. The decision followed a positive opinion by the European Medicines Agency (EMA)’s Committee for Medicinal Products for Human Use (CHMP) 3
A novel scheme for privacy preserving in RBAC
2013
Role Based Access Control (RBAC) Model has been proved to be quite useful and has drawn a lot of research interest over the last fifteen years. In this paper we discuss general context-aware RBAC model. We analyze potential privacy threats associated with use of context-aware RBAC and propose a novel scheme that provides privacy-preserving for access models based on RBAC.
The enabling factor: the influence of US-EU cooperation on UN peace operations
2011
The article analyzes the influence of US-EU cooperation on the UN decision-making process in the area of peace operations and its impact in the period 1991-2008. The article claims that US-EU cooperation transforms the positional power of the US, the EU and its member states into a coalition with dominant influence in the area of UN peace operations and becomes an enabling factor for the authorization of UN peace operations. The article analyzes the influence of US-EU cooperation on the UN decision-making process in the area of peace operations and its impact in the period 1991 - 2008. The article claims that US-EU cooperation transforms the positional power of the US, the EU and its member…
Development of extracellular vesicle-based medicinal products: A position paper of the group “Extracellular Vesicle translatiOn to clinicaL perspecti…
2021
International audience; Extracellular vesicles (EV) are emergent therapeutic effectors that have reached clinical trial investigation. To translate EV-based therapeutic to clinic, the challenge is to demonstrate quality, safety, and efficacy, as required for any medicinal product. EV research translation into medicinal products is an exciting and challenging perspective. Recent papers, provide important guidance on regulatory aspects of pharmaceutical development, defining EVs for therapeutic applications and critical considerations for the development of potency tests. In addition, the ISEV Task Force on Regulatory Affairs and Clinical Use of EV-based Therapeutics as well as the Exosomes C…
Transformations in Lifelong Guidance Provision
2012
In this chapter, the transformations taking place at the different levels of guidance provision are analyzed. The aim was to provide a tool to examine the interface between multisectoral guidance practice and policy development. On the basis of earlier research on regional guidance networks, a model is introduced in which schools, social, health, and public employment services can jointly design, implement, and evaluate guidance services. The model for Networked Guidance Service Provision (NEGSEP) focuses separately on the developmental needs of guidance services visible to clients, both with regard to service delivery and strategic dimensions. Along this line, a framework for networked gui…
Authentication and authorization security solution for the internet of thing
2021
The Internet of Things (IoT) represents the interconnection between the Internet and physical objects, places and environments. However, this extensive connectivity of IoT can be hampered by malicious interventions from cyber attackers. Thus, ensuring security for users and IoT devices remains a challenge, especially authentication and authorization, which are essential building blocks of the security process. This is due to the unconventional IoT characteristics, including scalability, heterogeneity, interoperability, and dynamic changes, which make the existing security measures inadequate. Indeed, these characteristics bring up several security requirements to consider when defining a se…
O Brasil na rota das migrações internacionais qualificadas espanholas no século XXI
2018
In order to understand recent migration, it is crucial to analyze the migratory modalities such as skilled international migration to Brazil, especially considering the ongoing transnational economic processes and their effects on the corresponding societies. Therefore, this article seeks to understand how the migratory dynamics of highly skilled Spanish professionals to the country are established taking into account the theoretical contribution of the circulation of brains and the category of knowledge workers. For this purpose, information from Brazilian?s Ministry of Labor is used on labor authorizations, financial contributions and insertion in the formal market in Spain; as well as da…
Cell therapy medicinal product regulatory framework in Europe and its application for MSC-based therapy development
2012
Advanced therapy medicinal products (ATMPs), including cell therapy products, form a new class of medicines in the European Union. Since the ATMPs are at the forefront of scientific innovation in medicine, specific regulatory framework has been developed for these medicines and implemented from 2009. The Committee for Advanced Therapies (CAT) has been established at the European Medicines Agency (EMA) for centralized classification, certification and evaluation procedures, and other ATMP-related tasks. Guidance documents, initiatives, and interaction platforms are available to make the new framework more accessible for small- and medium-sized enterprises, academia, hospitals, and foundation…
Normativitet: utfordring i psykoterapeutisk og pedagogisk arbeid. Den profesjonelle mellom tvang og frihet
2016
In this article we wish to discuss different normative dilemmas that teachers and psychotherapists meet in their work with the student and the patient. We argue that crucial for a good practice is not the actual choice between normativity and freedom, between generalized or authorized standards and individual dialogue. Rather it is the professional’s continuous reflection on the form and quality of the interactions with the pupil and the patient, and the preservation of the balance between personal ethos and professional responsibilities that best safeguard respect for the other's autonomy and self-determination. By illustrating psychotherapeutic malpractice and systematic mistreatment of c…