Search results for "Availability"
showing 10 items of 510 documents
A privacy-aware framework for decentralized online social networks
2015
Online social networks based on a single service provider suffer several drawbacks, first of all the privacy issues arising from the delegation of user data to a single entity. Distributed online social networks (DOSN) have been recently proposed as an alternative solution allowing users to keep control of their private data. However, the lack of a centralized entity introduces new problems, like the need of defining proper privacy policies for data access and of guaranteeing the availability of user's data when the user disconnects from the social network. This paper introduces a privacy-aware support for DOSN enabling users to define a set of privacy policies which describe who is entitle…
Soil Nitrogen Form and Availability affect the role of Arbuscular Mycorrhizal Fungi on Nitrogen Uptake and Nitrogen Recovery in Durum Wheat
2018
The term Arbuscular Mycorrhizal (AM) is referred to the symbiosis between arbuscular mycorrhizal fungi (AMF) and plant roots. Such symbiosis is the most widespread among plants (two out of three of the all plant taxa) including the majority of crops. AMF belong to the monophyletic subphylum Glomeromycotina which include obligate biotrophs that entirely relay on the host plant for the carbon source. In exchange, AMF provide their host several benefits which have been recognise in mitigation of biotic and abiotic stress, even though the main benefit ascribe to AMF is improving P uptake. However, although the AM symbiosis is considered as a classic example of a mutualistic symbiosis, many fact…
Conventional tillage versus no-tillage: Nitrogen use efficiency component analysis of contrasting durum wheat genotypes grown in a Mediterranean envi…
2023
Very little information is available for Mediterranean areas about the soil N dynamics and crop N use efficiency during the transition phase from conventional tillage (CT) to no-tillage (NT). Hence, a 2-yr experiment was conducted under semiarid Mediterranean conditions in three sites to study how soil N dynamics, crop N uptake, grain yield, and N use efficiency vary with N-fertilization rate and crop genotype in the switch year from CT to NT. Treatments consisted of two tillage systems (CT and NT), five N-fertilization rates (0, 40, 80, 120, and 160 kg N ha−1), and two durum wheat (Triticum durum Desf.) genotypes (one modern variety and one old landrace). Irrespective of the genotype, NT r…
BIOCHARS IN SOILS: TOWARDS THE REQUIRED LEVEL OF SCIENTIFIC UNDERSTANDING
2017
The special issue on Biochar as an Option for Sustainable Resource Management Key priorities in biochar research for future guidance of sustainable policy development have been identified by expert assessment within the COST Action TD1107. The current level of scientific understanding (LOSU) regarding the consequences of biochar application to soil were explored. Five broad thematic areas of biochar research were addressed: soil biodiversity and ecotoxicology, soil organic matter and greenhouse gas (GHG) emissions, soil physical properties, nutrient cycles and crop production, and soil remediation. The highest future research priorities regarding biochar’s effects in soils were: functional …
Transdermal and Skin-Targeted Drug Delivery
1997
Background: The application of therapeutic agents to the skin addresses three general objectives: (a) the treatment of a variety of dermatologic diseases; (b) the “targeted” delivery of drugs to deeper subcutaneous tissues, with a concomitant reduction in systemic exposure; and (c) socalled transdermal administration to elicit a systemic pharmacologic effect. Objective: Recently, significant progress towards all three goals has been recorded and the level of research and development activity remains high. We aim to discuss these advances from mechanistic and clinical standpoints. Results: For the topical treatment of skin disease, novel vehicles (e.g., stabilized, supersaturated systems and…
Basing the Analysis of Comparative Bioavailability Trials on an Individualized Statistical Definition of Equivalence
1993
The conventional definition of bioequivalence in terms of population means only, is criticized for lacking relevance to the individual subject. Both approaches to bioequivalence assessment proposed here for avoiding this shortcoming, focus on the probability of an event induced by the response of a randomly selected subject to two formulations of a given active agent. The first approach leads to converting the basic idea underlying the well-known 75-rule into an exact statistical procedure. The second approach is of a parametric nature. It reduces bioequivalence assessment to testing against the alternative hypothesis that the standardized expected value of a Gaussian distribution is contai…
Assessment of Modelling Structure and Data Availability Influence on Urban Flood Damage Modelling Uncertainty
2014
Abstract In modelling application, different model structures may be equally reliable in terms of calibration ability but they may produce different uncertainty levels; moreover, available data during model calibration may influence the uncertainty linked to the predictions of the same modelling structure. In the present paper, Bayesian model-averaging was applied to several flood damage estimation models in order to identify the best model combination for urban flooding distribution analysis in Palermo city center (Italy). During the analysis, was taken into account the effect of the available data growth on the model uncertainty with respect to the different combination of models outputs.
An analysis of ego network communities and temporal a affinity for online social networks
2017
The wide diffusion of Online Social Networks (OSNs) presents several advantages, like the definition of simple tools for information sharing and spreading. However, OSNs present also some drawbacks, one of the most important one is the problem of privacy disclosures. Distributed Online Social Networks (DOSNs), which decentralize the control of the social network, have been recently proposed to overcome these issues. The decentralization of the control has issued several challenges, one of the main ones is guaranteeing data availability without relying on a central server. To define users’ data allocation strategies, the knowledge of the structure of the ego network and of the user’ temporal…
Improvement of Resveratrol Permeation through Sublingual Mucosa: Chemical Permeation Enhancers versus Spray Drying Technique to Obtain Fast-Disintegr…
2021
Resveratrol (RSV) is a natural polyphenol with several interesting broad-spectrum pharmacological properties. However, it is characterized by poor oral bioavailability, extensive first-pass effect metabolism and low stability. Indeed, RSV could benefit from the advantage of the sublingual route of administration. In this view, RSV attitudes to crossing the porcine sublingual mucosa were evaluated and promoted both by six different chemical permeation enhancers (CPEs) as well as by preparing four innovative fast-disintegrating sublingual mini-tablets by spray drying followed by direct compression. Since RSV by itself exhibits a low permeation aptitude, this could be significantly enhanced by…
Petro-mineralogical controls on coda attenuation in volcanic rock samples
2021
SUMMARY Seismic attenuation measurements, especially those obtained from coda decay analysis, are becoming a key data source for the characterization of the heterogeneous Earth due to their sensitivity to small-scale heterogeneities. However, the relation between the scattering attenuation measured from coda waves and physical rock properties is still unclear. The goal of this study is to identify the main petrophysical and mineralogical factors controlling coda attenuation in volcanic rocks at the laboratory scale, as a necessary step before modelling seismic waves in real volcanic media. Coda wave attenuation was estimated from ultrasonic S-wave waveforms. To quantify the heterogeneity of…